Typing tool
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Typing tool
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Complete norovirus genomes
| PV241703 | GII.4 Hunter | |
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| GII.P4 Apeldoorn |
ORF1: 1..5092
ORF2: 5073..6695
ORF3: 6695..7501
LOCUS PV241703 7548 bp RNA linear VRL 28-JUL-2025
DEFINITION Norovirus GII isolate 100316 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION PV241703
VERSION PV241703.1
DBLINK BioProject: PRJNA1195142
BioSample: SAMN45209849
Sequence Read Archive: SRR31712830
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7548)
AUTHORS Ramani,S., Javornik Cregeen,S.J., Surathu,A., Muzny,D.M.,
Doddapaneni,H., Menon,V.K., Hoffman,K.L., Ross,M.C., Metcalf,G.,
Opekun,A.R., Graham,D.Y., Gibbs,R.A., Petrosino,J.F., Estes,M.K.
and Atmar,R.L.
TITLE Intra- and Inter-host Evolution of Human Norovirus in Healthy
Adults
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7548)
AUTHORS Ramani,S., Javornik Cregeen,S.J., Surathu,A., Muzny,D.M.,
Doddapaneni,H., Menon,V.K., Hoffman,K.L., Ross,M.C., Metcalf,G.,
Opekun,A.R., Graham,D.Y., Gibbs,R.A., Petrosino,J.F., Estes,M.K.
and Atmar,R.L.
TITLE Direct Submission
JOURNAL Submitted (06-MAR-2025) Molecular Virology and Microbiology, Baylor
College of Medicine, Alkek Center for Metagenomics and Microbiome
Research, 1 Baylor Plaza, Houston, TX 77030, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: VirMap v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7548
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="100316"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA: Houston"
/collection_date="03-Feb-2005"
/note="genotype: GII.4"
gene <1..5092
/gene="ORF1"
CDS <1..5092
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XPO69240.1"
/translation="ASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARPKQP
PPREIPQRPLRPPTPELVKNIPPPPPNGEDEIVVSYSVKDGVSGLPDLSTVRQPEESN
TAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISLAR
VELTPLSLFWRPVYTPQYLISPDALKKLHGETFPYTAFDNNCYAFCCWVLDLNDSWLS
RRMIQRTTGFFRPYQDWNRKPLPTVDDSKLKKVANIFLCALSSLFTRPIKDIVGKIRP
LNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAV
ELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKE
EANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSA
SPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREVAKR
IAASLTGDQRVGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLT
LNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPDVEKAKR
DFPGQPDMWKNAFSSDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGL
LHERLDEFELQGPTLTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVRTMPEL
KQALKNISIKKCQIVYSGCTYTLESDGKGNVKVDRVQSASVQTNNELTGALHHLRCAR
IRYYVKCVQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQVENTEEATSRDGCPKP
KDDEEFVISSDDLKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERSGKYS
IEEYLQDRDKYYEEVAIARATEENFCEEEEAKIRQRIFRPTRKQRKEERASLGLVTGS
EIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPSLF
ITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVV
TLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGC
PYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNRGTYCGAPILGPGS
APKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGK
PPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCWNGE
SFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLATM
IRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWDSTQ
QRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTSQW
NSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLREYG
LKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGSNHE
DPSETMVPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMF
RWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..982
/gene="ORF1"
/product="p48"
mat_peptide 983..2080
/gene="ORF1"
/product="NTPase"
mat_peptide 2081..2617
/gene="ORF1"
/product="p22"
mat_peptide 2618..3016
/gene="ORF1"
/product="VPg"
mat_peptide 3017..3559
/gene="ORF1"
/product="Pro"
mat_peptide 3560..5089
/gene="ORF1"
/product="RdRp"
gene 5073..6695
/gene="ORF2"
CDS 5073..6695
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XPO69241.1"
/translation="MKMASNDATPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGTQNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRGDGSTRGHKATVSTGSVHFTPKLGSIQFSTDTSNDFDTHQNTRFTPVGVVQDG
STTHQNEPQQWVLPNYSGRDSHNVHLAPAVAPSFPGEQLLFFRSTMPGCSGYPNMNLD
CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 6695..7501
/gene="ORF3"
CDS 6695..7501
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XPO69242.1"
/translation="MAGAFFAGLASDVLSSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAVN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRTNLRAAVPARGSSSTLS
NTSAATSVYSNQTASTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 ggcgtctaac gacgcttccg ctgccgctgt tgctaacagc aacaacgaca ccgcaaaatc
61 ttcaagtgac ggagtgcttt ctagcatggc tgtcactttt aaacgagccc tcggggcgcg
121 gcctaagcag cctcccccga gggaaatacc acaaagaccc ctacggccac ctactccaga
181 actggtcaaa aatatccccc ctcccccgcc caacggagag gatgaaatag tggtttctta
241 tagtgtcaaa gatggtgttt ccggtttgcc tgatctttcc accgtcagac aaccggaaga
301 atccaacacg gctttcagtg tccctccact caatcagagg gagaatagag atgctaagga
361 gccactgact ggaacaattc tggaaatgtg ggatggagaa atctaccatt atggcctgta
421 tgtggagcga ggtcttgtac tgggtgtgca caaaccacca gctgccatta gcctcgctag
481 ggtcgaacta acaccactct ccttgttctg gagacctgtg tatactcctc agtacctcat
541 ctctccagac gctctcaaga aattacacgg agagacgttc ccctacacag cctttgacaa
601 caattgctat gccttttgtt gctgggtcct ggacctaaat gactcgtggc tgagtaggag
661 gatgatccag agaacaactg gcttcttcag gccctaccaa gattggaata ggaaacccct
721 ccccactgtg gatgactcca aattgaagaa ggtagctaac atattcctgt gtgctctgtc
781 ttcgctattc accaggccca taaaagatat agtagggaag ataaggcctc ttaacatcct
841 caacattttg gcctcatgtg attggacttt tgcaggcata gtggagtcct tgatactctt
901 ggcagaactc tttggagttt tctggacacc cccagatgtg tctgcgatga ttgccccctt
961 actcggtgat tacgagctac aaggacctga ggaccttgca gtggagctcg tccctgtagt
1021 gatgggtgga attggtttgg tgctaggatt caccaaagag aagattggaa agatgttgtc
1081 atctgctgca tccaccttga gagcttgtaa agatcttggt gcatatgggc tagagatcct
1141 aaagttggtc atgaagtggt tcttcccgaa gaaagaggaa gcaaatgaac tggctatggt
1201 gagatccatc gaggatgcag tcctggatct cgaggcaatt gaaaacaacc atatgaccac
1261 cctgctcaaa gacaaagaca gtctggcaac ctacatgaga actcttgacc ttgaggagga
1321 gaaagccagg aaactctcga ccaagtctgc ctcacctgac atcgtgggca caatcaacgc
1381 ccttttggcg agaatcgctg ctgcacgttc tctggtgcat cgagcgaagg aggaactttc
1441 cagcagacca agacctgtag tattgatgat atcaggcaga ccaggaatag ggaagaccca
1501 ccttgctagg gaagtggcta agagaatcgc agcctccctc acaggagacc agcgtgtagg
1561 cctcgtccca cgcaatggcg tcgaccattg ggatgcgtac aagggggaga gggtcgtcct
1621 atgggacgac tatggaatga gcaatcccat ccacgatgcc ctcagattgc aagaactcgc
1681 tgacacttgc cccctcactc taaactgtga caggatcgag aataaaggaa aggtctttga
1741 cagcgatgtc atcattatca ccaccaatct ggccaaccca gcaccactgg actatgtcaa
1801 ctttgaagca tgctcgaggc gcatcgactt cctcgtgtat gcagaagccc ccgatgtcga
1861 aaaggcgaag cgtgacttcc caggccaacc tgacatgtgg aagaacgcct tcagttccga
1921 cttctcacac ataaaactaa cattggcccc acagggtggt ttcgacaaga acgggaacac
1981 cccacatgga aagggcgtca tgaagactct caccactggc tcccttattg cccgggcatc
2041 agggctactc catgagaggc tagatgaatt tgaactacag ggcccaactc tcaccacctt
2101 caactttgat cgcaataaag tgcttgcctt tagacaactc gctgctgaaa acaaatatgg
2161 actgatggac acaatgaaag ttgggaggca gctcaaggat gtcagaacca tgccagagct
2221 taaacaagca ctcaagaata tctcaattaa gaagtgccaa atagtgtata gtggttgcac
2281 ctacacactt gagtctgatg gcaagggcaa tgtgaaagtt gacagagttc agagcgcctc
2341 cgtgcagacc aacaatgaac tgactggcgc cctgcaccat ttaaggtgtg ccagaatcag
2401 atactatgtc aagtgtgtcc aggaggccct gtattccatc atccagattg ctggggctgc
2461 atttgtcacc acgcgcatcg tcaagcgcat gaacatacaa gacctatggt ccaagccaca
2521 agtggaaaac acagaggagg ctaccagtag ggacgggtgc ccaaaaccca aagatgatga
2581 ggagttcgtc atctcatccg acgacctcaa aactgagggt aagaaaggga agaacaagac
2641 tggccgcggc aagaagcaca cagccttctc aagcaaaggt ctcagtgatg aagagtacga
2701 cgagtacaag aggattagag aagaaaggag tggcaagtac tccatagaag aataccttca
2761 ggacagggac aaatactatg aggaggtggc cattgccagg gcgaccgagg aaaacttctg
2821 tgaagaggag gaggccaaga tccggcaaag gatcttcagg ccaacaagga aacaacgcaa
2881 ggaggaaaga gcttctctcg gtttagttac aggttctgaa attaggaaaa gaaacccaga
2941 tgatttcaaa cccaagggga aactgtgggc tgacgatgac agaagtgtgg actacaatga
3001 gaaactcagt tttgaggcac caccaagcat ctggtcgagg atagtgaact ttggttcagg
3061 ttggggattc tgggtctccc ccagtctgtt cataacatca acccatgtca taccccaggg
3121 cgcaaaggag ttctttggag tccccatcaa acaaattcag gtacacaagt caggcgaatt
3181 ctgtcgcttg agattcccaa aaccaatcag gactgatgtg acgggcatga tcttagaaga
3241 aggtgcaccc gagggcaccg tggtcacact actcatcaaa aggtctactg gagaactcat
3301 gcccctagca gctaggatgg ggacccatgc aaccatgaaa atccaagggc gcactgttgg
3361 aggccaaatg ggcatgcttc tgacaggatc caacgccaaa agcatggacc tgggtaccac
3421 accaggtgat tgtggctgtc cctacatcta caagagagga aatgactatg tggtcattgg
3481 agtccacacg gctgccgccc gtggggggaa cactgtcata tgtgccaccc aggggagtga
3541 gggagaggct acacttgaag gtggtgacaa tagggggaca tactgtggtg caccaatcct
3601 aggcccaggg agtgccccaa aacttagcac caagaccaaa ttctggagat cgtccacagc
3661 accactccca cctggcacct atgaaccagc ctatcttggt ggcaaagacc ccagagtcaa
3721 gggtggccct tcactgcagc aagtcatgag ggatcagttg aagccattca cagagcccag
3781 aggcaagcca ccaaagccaa gtgtgttaga agctgccaag aaaaccatca tcaatgtcct
3841 tgagcaaaca attgatccac ctgagaaatg gtcattcgcg caagcctgcg cgtcccttga
3901 caagaccact tccagtggcc atccgcacca catgcggaaa aacgactgct ggaacgggga
3961 gtccttcaca ggcaagctgg cagaccaggc ttccaaggcc aacctgatgt ttgaagaagg
4021 gaagaacatg accccagtct acacagctgc gcttaaggat gaattggtta aaactgacaa
4081 aatttatggt aagatcaaga agaggcttct ttggggctcg gatttagcga ccatgatccg
4141 gtgtgctcga gcattcggag gcctaatgga tgaactcaaa gcacactgtg tcacacttcc
4201 cattagggtt ggtatgaata tgaatgagga tggccccatc atcttcgaga ggcattccag
4261 gtacacatat cactatgatg ctgattactc ccgatgggat tcaacacaac agagagccgt
4321 gttggcagca gctctagaaa tcatggttaa attctcccca gaaccacatt tggctcaggt
4381 agtcgcagaa gatcttcttt ctcctagcgt ggtggacgtg ggtgacttca caatatcaat
4441 caacgagggt cttccctccg gggtgccctg cacctcccaa tggaactcca tcgcccactg
4501 gcttctcacc ctctgtgcgc tctctgaagt tacaaacttg tcccctgaca tcatacaggc
4561 taattccctc ttctcttttt atggtgatga tgaaattgtt agcacagaca taaaattgga
4621 cccagagaag ttgacagcaa agctcaggga atatgggtta aaaccaaccc gccctgacaa
4681 aactgaagga ccccttgtca tctctgaaga cttaaatggc ctgactttcc tgcggagaac
4741 tgtgacccgc gacccagctg gttggtttgg aaaactggag cagagttcaa tactcaggca
4801 aatgtactgg actaggggct ccaaccatga agacccatct gaaacaatgg ttccacactc
4861 ccaaagaccc atacaattga tgtcactact gggggaggcc gcactccacg gcccagcatt
4921 ctacagtaaa atcagcaagt tagttattgc agagctaaaa gaaggtggca tggattttta
4981 cgtgcccaga caagagccaa tgttcagatg gatgagattc tcagatctga gcacgtggga
5041 gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgaat gacgccaccc
5101 catctgatgg gtccacagcc aacctcgtcc cagaggtcaa caatgaggtt atggctttgg
5161 agcccgttgt tggtgccgct atcgcggcac ctgtagcggg ccaacaaaat gtaattgacc
5221 cctggattag aaataatttt gtacaagccc ctggtggaga gtttacagtg tcccctagaa
5281 acgctccagg tgaaatacta tggagcgcgc ccttgggccc tgatttgaac ccctaccttt
5341 cccatttggc cagaatgtac aatggttatg caggtggttt tgaagtgcag gtaattctcg
5401 cggggaacgc gtttaccgcc ggaaaaatca tatttgcagc agtcccacca aatttcccaa
5461 ctgaaggctt gagccccagc caggtcacga tgttccccca tataatagta gatgttaggc
5521 aactggaacc tgtgttgatc cccttacctg atgttaggaa taatttctat cattacaatc
5581 agtcaaatga tcccaccatc aaattgatag caatgctgta tacaccactt agggctaata
5641 atgctgggga cgatgtcttc acagtctctt gtcgagttct cacgaggcca tcccccgact
5701 ttgatttcat atttttggtg ccacccacag ttgagtcaag aactaaacca ttctctgttc
5761 caattttaac tgttgaggag atgaccaatt caagattccc cattcctttg gaaaagttgt
5821 tcacgggtcc cagcagtgcc tttgttgttc aaccacaaaa tggcagatgc acgactgatg
5881 gcgtgctttt aggtactacc caactgtctc ctgtcaacat ctgcaccttc agaggggatg
5941 tcacccacat tgcaggcact caaaattaca caatgaatct ggcctcccaa aattggaaca
6001 attatgaccc gacagaagaa atcccagccc ctctgggaac tccagatttt gtgggaaaga
6061 tccaaggcgt gctcacccaa accacaaggg gggatggctc gacccgcggc cacaaagcca
6121 cagtgagcac tggaagtgtc cacttcaccc caaagctggg cagtattcaa ttctccactg
6181 atacaagcaa tgactttgac actcaccaaa acacgagatt caccccagtc ggtgtcgtcc
6241 aggatggtag taccacccac caaaatgaac cccaacaatg ggtgctccca aattattcag
6301 gtagagatag tcataatgta cacctagccc ctgccgtggc cccctctttt ccgggtgagc
6361 aacttctttt cttcaggtcc actatgcccg gatgcagcgg gtatcccaac atgaatttgg
6421 attgcctact cccccaagag tgggtgcagc acttctacca agaggcagcc ccagcacaat
6481 ctgatgtggc tctgctaaga tttgtgaatc cagacacagg tagggttctg tttgagtgca
6541 agcttcataa atcaggctat gtcacagtgg ctcacactgg ccaacatgac ttggttattc
6601 cccccaatgg ctattttaga tttgattcct gggtcaacca gttctacacg cttgccccca
6661 tgggaaatgg agcggggcgc agacgtgcat tataatggct ggagctttct ttgctggatt
6721 ggcatctgat gtccttagct ctggacttgg ttccctaatc aacgctgggg ctggggccat
6781 caaccaaaaa gttgaatttg aaaataacag aaaattgcaa caagcttcct tccaatttag
6841 cagcaacctg caacaggcct cctttcaaca tgataaagag atgctccaag cacaaattga
6901 ggccaccaaa aagttgcagc aagaaatgat gaaagtcaaa caggcaatgc tcctagaggg
6961 tgggttctct gagacagatg cagcccgtgg ggcagtcaac gcccctatga caaaggcttt
7021 ggattggagc ggaacaaggt actgggctcc cgacgctagg actacaacat acaatgcagg
7081 ccgcttttcc accccacaac cctcgggggc actgccagga agaactaacc tcagggctgc
7141 tgtccccgct cggggctcct ccagtacact ttctaatact tctgctgcta cttctgtgta
7201 ctcaaatcaa actgcttcaa cgagacttgg ttctacagct ggttctggta ccagtgtctc
7261 gagcctcccg tcaactgcaa ggactaggag ctgggttgag gatcaaaaca ggaatttgtc
7321 acctttcatg aggggggccc acaacatatc gtttgtcacc ccaccatcta gtagatcctc
7381 tagtcaaggc acagtctcaa ccgtgcctaa agaagttttg gactcctgga ctggcgcttt
7441 taacacgcgc aggcagcctc tcttcgctca cattcgtaag cgaggggagt cacgggcgta
7501 atgtgaaaag acaatattga ttatctttct tttttttttt tttttttt
//