Typing tool
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Typing tool
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Complete norovirus genomes
| PQ373125 | GII.17 | |
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| GII.P17 |
ORF1: 1..5109
ORF2: 5090..6709
ORF3: 6709..7488
LOCUS PQ373125 7513 bp RNA linear VRL 30-SEP-2024
DEFINITION Norovirus GII isolate RIVM-NL-NoV16-45 nonstructural polyprotein
(ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION PQ373125
VERSION PQ373125.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7513)
AUTHORS Vennema,H., Cremer,J., Jaarsma,R., van der Veer,B., Schmitz,D.,
Zwagemaker,F. and Kroneman,A.
TITLE Direct Submission
JOURNAL Submitted (25-SEP-2024) Centre for Infectious Disease Control,
National Institute for Public Health and the Environment, Antonie
Van Leeuwenhoeklaan, Bilthoven, Utrecht 3721 MA, Netherlands
COMMENT ##Assembly-Data-START##
Assembly Method :: Jovian v. 2.0.1
Sequencing Technology :: Sanger dideoxy sequencing; Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7513
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="RIVM-NL-NoV16-45"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Netherlands"
/collection_date="11-Nov-2016"
/note="genotype: GII.17"
gene 1..5109
/gene="ORF1"
CDS 1..5109
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XHF05696.1"
/translation="MKMASNDASVAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGAR
PKQPPPGETKQTQRPPRPPTPELVKKIPPPPPNGEDEPKIAYKVGEGVSGLPDLTTVA
QPDAQNTAYSVPPLSQREAGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPA
AISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLSGETFPYTAFDNNCYAFCCWVLDL
NDSWLSRRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDI
IGKLRPLNILNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMVAPLLGDYEMQG
PEDLAVELVPVVMGGVGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKW
FFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDLEEEKARK
LSTKSASPDIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLA
RELAKKVASTLTGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPD
IEKAKRDFPGQPDMWKDHYRPDFTHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLI
ARASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLKVGNQLKSV
KTLDELKQAIKNINIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALH
HLRSARIRYYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPVEEGDEPEDK
GGCPKPRDEDDLTIDSKDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATL
GLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFW
VSPSLFITSTHVIPKGITEAFGVPMSQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGA
PEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGNEGEATLEGGDNKGTYCGAP
ILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPKPNVLESAKRTIINVLEQTIDPPEKWSYVQACASLDKTTSSGYPHHVRKN
DYWSGETFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWG
SDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTA
KLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWT
RGPNHEDPSETMVPHAQRPVQLMALLGESSLHGPSFYSKISKLVISELKEGGMDFYVP
RQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 1..999
/gene="ORF1"
/product="p48"
mat_peptide 1000..2097
/gene="ORF1"
/product="NTPase"
mat_peptide 2098..2634
/gene="ORF1"
/product="p22"
mat_peptide 2635..3033
/gene="ORF1"
/product="VPg"
mat_peptide 3034..3576
/gene="ORF1"
/product="Pro"
mat_peptide 3577..5106
/gene="ORF1"
/product="RdRp"
gene 5090..6709
/gene="ORF2"
CDS 5090..6709
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XHF05697.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGV
ASQRNVGNDAPGSTRAHEAVISTYSPKFVPKLGSVNFRSNDDDFQLQPTRFTPVGINE
DDSNHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIIDC
LIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVV
PANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6709..7488
/gene="ORF3"
CDS 6709..7488
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XHF05698.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVKATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHVPSPIAPQSKPTKPRSLAPSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgtt gccgttgctg gcaagaataa caacaacgac
61 aaggaaaaat cttcaagtga cagcttgttt tctaacatga ctgttacttt taagaaagcc
121 ctcggggcgc ggcctaaaca gccgcccccg ggagaaacaa aacaaacaca aagaccacca
181 agaccaccga caccggaatt ggtgaagaaa atacccccac ccccacccaa tggcgaggat
241 gaaccaaaaa tagcgtacaa ggtgggagag ggtgtgtccg ggctgcccga cctgacaact
301 gtggcacagc ctgacgcaca aaacacagcc tatagtgttc ccccactcag ccagagagag
361 gccggcgaag ctaaagaacc gttgcctggc tctattctgg aaatgtggga cggtgagatc
421 taccactatg ggctgtatgt tgagcggggg catgtactcg gagtacacaa accacctgct
481 gcaataagcc ttgccaaaat tgaattaaca ccgctgtctc tctactggag agtggtctac
541 actccccagt atttgatagc tccagaaact cttaagaact taagtggaga gacttttcca
601 tacacggcct ttgacaacaa ctgttatgcc ttctgttgtt gggtcctaga cctcaacgac
661 tcctggctta gcaggagaat gatccaaaga acaactggat tcttcagacc gtatcaggat
721 tggaacagaa aacccttgcc aaccatggat gaaccgaaaa tcaagaaggc cgcgaatgct
781 gttctgtgtg ctctctcctc actcttcact agacccatca aagacatcat tggaaagctt
841 agaccactga acattcttaa tatactggca acttgtgatt ggacttttgc gggcatagtg
901 gaatccatga tccttcttgc tgaactcttt ggggtgttct ggaccccccc agatgtgtct
961 gcgatggttg ctcccttact cggtgactac gagatgcaag gccccgaaga tctggccgtg
1021 gaacttgtgc ccgtggtaat gggaggagta ggtttggtgt taggattcac caaggaaaag
1081 atcggcaaga tgctttcatc agctgcgact acactcaggg cctgtaagga tctaggatct
1141 tatgggttgg agatactcaa actggtcatg aagtggttct tccccaagaa ggaggaggcc
1201 aacgagttag ccatggtgag ggccattgag gatgcagtcc tggatttgga ggcaatagaa
1261 aacaatcaca tgaccaccct tctcaaggac aaagacagcc tggccacata catgaagact
1321 cttgacttgg aagaagaaaa agcgaggaaa ctgtcaacca agtcggcgtc acctgacatc
1381 gtgggcacaa taaacgcatt attggcaagg atagcagccg ccaggtcact ggttcacaag
1441 gctaaggagg agctctcgag cagacagaga cctgttgttg taatgatatc aggtagacca
1501 ggtataggaa agacccatct ggccagagag ctagccaaga aagttgcgtc aacactgaca
1561 ggcgaccaaa ggattggact gatacctaga aatggcgtcg accattggga cgcctacaaa
1621 ggagagaggg tagttctgtg ggatgattat ggcatgagca accctataca ggacgcactg
1681 aggctccaag aattggccga cacctgtcct ctgaccctaa attgtgacag gattgaaaac
1741 aaaggaaaag tgttcgacag tgacgccata atcataacaa ccaaccttgc aaacccagca
1801 ccactggact atgtcaactt tgaggcttgt tctagacgca tagacttctt agtgtatgca
1861 gacgcacctg acattgagaa ggccaagcgt gatttccctg gccaaccaga tatgtggaaa
1921 gaccattaca gaccagactt cacacacatt aaacttcagt tggcaccaca gggaggcttt
1981 gataaaaatg gtaacacccc acatggcaaa ggtgtggtga agtctctgac gattggctct
2041 ctgatcgcca gggcttctgg cttgctccac gagagaatgg atgaatttga gctccaaggc
2101 tctgacctgc caaccttcaa tttcgaccgc aacaaagtcg ccgccttcag gcaattggca
2161 gctgaaaaca aatatggtct tatggacaca ttgaaggtcg gcaaccaatt gaaaagtgtc
2221 aaaaccctgg atgagctaaa gcaggccata aagaacatca atatcaaaaa gtgccagata
2281 gtgtataatg ggtgcaccta tactatggaa tctgatggga ggaacaaggt tgtggttgaa
2341 aaggttcaaa atgcaacagt tcaaaccaac aatgaacttg caggagcact ccaccacctg
2401 agatctgcaa ggataagata ttatgttaaa tgtttccaag aagctattta ctctctgctc
2461 caaatcgctg gtgcagcctt cgtcacctca cgcatcgtga ggcgcatgaa catctcaaac
2521 ctctggtcga agccacctgt cgaggagggt gatgagcctg aagacaaagg aggatgcccc
2581 aagcccaggg atgaagatga cctcactatt gactctaaag acattaaagt ggaagggaag
2641 aagggcaaga acaaatctgg ccggggcaag aaacacacag ctttctcatc caagggcctc
2701 agtgatgaag agtatgacga gtacaagaga atcagagagg agaggaatgg caaatactca
2761 atagaggaat acctccaaga tagggataga tactatgaag agcttgccat tgctaaggcc
2821 actgaggaag acttctgtga agaggaggaa atcaaaattc gccagagaat tttccgaccc
2881 actaggaagc agcggaaaga ggaaagagcc acgcttgggc ttgtcacagg atcggaaatc
2941 agaaagagga atccagatga ctttaaacca aaaggaaaat tgtgggctga tgacaacagg
3001 agtgtggatt acaatgagag gatagatttt gaggctcccc cgagtgtttg gtctaggata
3061 gtcaactttg gtacaggatg gggattctgg gtttctccaa gtctctttat aacttcaaca
3121 cacgtcatac caaaaggaat cactgaggct tttggagtgc ccatgagcca aatccaaatt
3181 cacaaatctg gagaattctg ccgcttgcgg tttccaaaac caatcagacc agacgtgagt
3241 gggatgatct tggaggaggg tgcccctgaa ggcaccgttg tgtccattct tatcaagagg
3301 acaacagggg agctgatgcc tctcgcagtc agaatgggga ctcatgccac aatgaaaatc
3361 caaggtagaa ctgtgggtgg tcagatgggt atgcttctca ctggctcgaa tgctaaaagt
3421 atggatctag gcacaacacc aggtgattgt gggtgcccat acatatacaa aaggggcaat
3481 gacttcgtgg tcattggggt acacactgca gcagctcgtg gaggcaatac ggtcatatgt
3541 gccacacagg gaaatgaagg tgaagccact ctcgaaggag gtgacaacaa gggcacctat
3601 tgtggagccc ccattttggg acctggcaat gcaccaaaat tgagcacaaa aacaaaattc
3661 tggagatctt ctaacgcacc gcttcccccg ggtacttatg aaccagcata ccttggtgga
3721 agagacccgc gtgtgaaggg aggcccatct ctgcaacagg ttatgagaga ccaacttaaa
3781 cctttcacag agcccagggg gaagccacca aaaccaaatg tcctagaatc agcaaagagg
3841 actatcatca atgttctgga acaaaccatt gacccccctg aaaagtggtc atatgtccaa
3901 gcttgtgcgt ccctcgacaa gacaacctcc agtggatacc cgcatcacgt ccggaagaat
3961 gactattgga gtggtgaaac tttcacgggg aaacttgcag accaggcctc aaaagcaaat
4021 ctcatgtatg aggaaggcaa gcacatgcaa ccagtttaca ccgcagcact caaagacgag
4081 ctcgtgaaaa ctgacaaaat ttatggcaag atcaagaaaa ggctcctgtg gggttctgac
4141 ctatccacca tgattcgatg cgccagagca tttggtggtc tcatggatga gctcaaagca
4201 aattgtatca cactccctat cagagttggt atgaacatga atgaagatgg tcccataata
4261 tttgaaaaac actccaggta caggtaccac tatgatgctg attactcccg ctgggactcc
4321 acacagcagc gggcagtgct ggaagcggca cttgaaatca tggtgagatt ttctgctgag
4381 ccacagctgg cacaaatagt ggcagaggac ctgctgtcac caagtgtggt tgatgtgggc
4441 gacttcaaaa tcgctatcaa tgaaggccta ccatctggcg tgccttgcac ctcacaatgg
4501 aattccattg cccactggtt actcaccctg tgtgccctat ctgaagtgac aggactgggt
4561 cctgacatca tacaagccaa ctccatgtac tctttctatg gtgatgatga gattgtgagc
4621 acagacataa aactggaccc agagaaattg actgcaaagc tcaaagagta tggccttaaa
4681 cctacccggc ccgacaaaac tgaggggccg ctggtgatta gtgaagacct gaatgggttg
4741 actttcctcc gccgaacagt cacccgcgat ccagcaggtt ggttcggaaa gttggaccaa
4801 aactccatcc tcaggcagct gtactggaca agaggaccca accatgaaga ccccagtgag
4861 accatggtac cacacgcaca gagacctgtg cagctcatgg cattactagg agaatcctcc
4921 ctacatggac cctcatttta cagcaagatt agcaagctag tcatatctga acttaaagag
4981 ggaggaatgg atttttatgt gcccagacaa gagtcaatgt tcagatggat gaggttctca
5041 gatctaagca catgggaggg cgatcgcaat ctggctccca gttttgtgaa tgaagatggc
5101 gtcgaatgac gccgccccat ctaatgatgg tgctgctggt ctcgtaccag agggcaacaa
5161 cgagaccctt cccctagaac cagttgcggg cgcagctata gccgcacccg tcactggcca
5221 aaataacata attgacccct ggattagaac aaattttgtg caagcaccaa atggagagtt
5281 tacagtgtca cccagaaact ctcctggaga aattttacta aacctagagt tgggccctga
5341 tctgaaccct tatttggctc atttgtcaag gatgtacaat gggtatgctg gtggagtgga
5401 agttcaggtt ctcctggcag ggaacgcgtt cactgccggg aagatcctct tcgccgccgt
5461 cccgccaaat ttcccagtgg aattcttaag cccagcccag attacaatgc tcccacatat
5521 aatagtagat gttaggactc ttgaaccaat catgatccca ctacctgatg ttaggaacac
5581 attcttccat tataataacc agcccaacag ccgtatgaga ttagtggcta tgctctatac
5641 cccccttaga tctaatggtt caggtgatga tgtttttact gtttcctgta gggttttgac
5701 taggcccact cctgattttg agtttactta tttagtgcca ccttcagttg aatccaagac
5761 taagcctttc tccttaccca ttctaaccct ttctgagctc acaaattcga ggttcccagt
5821 ccccatcgat tcgcttttca ctgcccagaa taatgtgtta caggtacagt gtcaaaatgg
5881 caggtgcaca cttgatggtg agttacaagg cacaactcag ttgctcccat ctggcatctg
5941 tgcattcaga ggacgggtga cagcagaaac tgacaatcct gacaagtggc acatgcaact
6001 gcaaaacctc aatggcacaa catatgaccc aactgatgat gtgccagccc cactgggtac
6061 acctgacttc aagggcgtcg tgtttggggt agcaagccaa agaaatgtgg gcaacgatgc
6121 gcctggctca accagggccc atgaggcggt gatttcaacc tatagcccca aatttgtccc
6181 caaattaggc tctgttaatt ttagaagtaa tgatgatgat ttccagttgc agcccacaag
6241 attcacacca gtgggcatca atgaagatga tagcaaccac ccgttcagac aatgggaact
6301 accagactat tcaggggtgc ttaccttgaa tatgaatctt gcccccccgg ttgctccaaa
6361 tttccctggt gaacaattat tattcttcag atctttcgtg ccgtgttcag gaggttataa
6421 ccaaggcatc atagattgtc ttattcccca agaatggatc caacacttct atcaggaatc
6481 agcaccctcc cagtcagacg tggccctaat caggtatgtc aaccccgaca cgggacgcac
6541 actgtttgaa gcaaaattac acagatctgg ctacatcact gtggctcact ctggagacta
6601 tcctcttgtt gttccggcta atggatactt tagatttgat tcttgggtaa atcagtttta
6661 ctcactcgcc ccaatgggaa ctgggaatgg gcgaaggagg gctcagtaat ggctggagct
6721 ttcattgcag gattggcagg cgacatgctc acgtcatctg tgggttccct ggtgaatgca
6781 ggggcaaacg ccatcaatca aaagatagac tttgaaaaca acaaacaact ccagtctgct
6841 tcctttcagc atgataaaga gatgctccaa gcgcaggtga aagcaaccaa gcagctgcaa
6901 tctgaaatga tagccctaaa acagggggtt ttggccgcag gcggcttttc ccccactgat
6961 gcagcaaggg gagccatcgg tgcacccatg acaaaggtgc ttgactggtc tggcactcga
7021 tactgggcac ccaattccac aaagacaact ggttattcgg ggcaatttac ctcttcacct
7081 gtgcacgtgc ctagcccgat tgctccacaa tcaaaaccca caaaacccag gtctctagct
7141 ccttcctcct cttctagtag tgtctatagt atgtccactc aattaacctc tctaacatct
7201 ggctcttcta gtaatgcttc ttcagcctct acaaaattaa caaatttaag ctctggctcc
7261 tctcaaaaca gaacagcaga gtgggtgaac caacagagaa gtcttagccc tttcatgagt
7321 ggcgcactca atatctcaca tgtcacgcca ccctcaagta gggcctccag ttctgggacg
7381 gtctcgaccg tgcccaagga agttttggac tcctggacat ctgcattcaa cacacgcaga
7441 caaccgctct tcgcacacct cagagtgagg ggggagtcac gtgtttagtg aaaagaaata
7501 attggctata ata
//