Typing tool
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Typing tool
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Complete norovirus genomes
| PQ336943 | GII.17 | |
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| GII.P17 |
ORF1: 1..5041
ORF2: 5022..6638
ORF3: 6638..7367
LOCUS PQ336943 7367 bp RNA linear VRL 17-OCT-2024
DEFINITION Norovirus GII isolate Hu/NL/2023/GII.17[P17]Rotterdam/100239
nonstructural polyprotein (ORF1) gene, partial cds; VP1 (ORF2)
gene, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION PQ336943
VERSION PQ336943.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7367)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7367)
AUTHORS de Graaf,M.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2024) Viroscience, Erasmus MC, Wytemaweg 80,
Rotterdam 1055SV, Netherlands
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7367
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/NL/2023/GII.17[P17]Rotterdam/100239"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Netherlands"
/collection_date="28-Apr-2023"
/note="genotype: GII.17"
gene <1..5041
/gene="ORF1"
CDS <1..5041
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XGX96929.1"
/translation="SSSDSLFSNMTVTFKKALGARSKQPPPGETKQTQRPPRPPTPEL
VKKIPPPPPNGEDEPKIAYKVGEGVSGLPDLTTVAQPDAQNTAYSVPPLSQREVGEAK
EPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAKIELTPLSLYWRVVYTPQ
YLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLSRRMIQRTTGFFRPYQDW
NRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIGKLKPLNIMNILATCDWTFAGI
VESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAVELVPVVMGGIGLVLGFT
KEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKEEANELAMVRAIEDAVLD
LEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSSKSASPDIVGTVNALLARIAA
ARSLVHKAKEELSSRQRPVVVMLSGRPGIGKTHLARELAKKVASTLSGDQRIGLVPRN
GVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLNCDRIENKGKVFDSDA
IIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDFPGQPDMWKDHYRSDF
SHIKLQLAPQGGFDKNGNTPHGKGVVKSLTVGSLIARASGLLHERMDEFELQGSDLPT
FNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQAIKNITIKKCQIVYN
GCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHLRSARIRYYVKCFQEAIYSLLQ
IAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKEGCPKPRDEDDLTIDSKDIKAEG
KKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAI
AKATEEDFCEEEEIKIRQRIFRPTRKQRRDERATLGLVTGSEIRKRNPDDFKPKGKLW
ADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPKGITEAFGV
PINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTGELMPLAVR
MGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDFVVIGVHT
AAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTKFWRSSNAP
LPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLESAKKTIINV
LEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQASKANLMY
EEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGGLMDELKAN
CIILPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAALEIMVRFSA
EPQLAQIVAEDLLSPSVVDVGDFKIVINEGLPSGVPCTSQWNSIAHWLLTLCALSEVT
GLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVISE
DLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPHAQRPVQLM
ALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRWMRFSDLSTWEGDRNL
APSFVNEDGVE"
mat_peptide <1..931
/gene="ORF1"
/product="p48"
mat_peptide 932..2029
/gene="ORF1"
/product="NTPase"
mat_peptide 2030..2566
/gene="ORF1"
/product="p22"
mat_peptide 2567..2965
/gene="ORF1"
/product="VPg"
mat_peptide 2966..3508
/gene="ORF1"
/product="Pro"
mat_peptide 3509..5038
/gene="ORF1"
/product="RdRp"
gene 5022..6638
/gene="ORF2"
CDS 5022..6638
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGX96930.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6638..>7367
/gene="ORF3"
CDS 6638..>7367
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGX96931.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKPRSLGSSSSSSSVYSMSTQST
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTR"
ORIGIN
1 atcttcaagt gacagcttgt tttctaacat gactgttact tttaagaaag ccctcggggc
61 gcggtctaaa cagccgcccc cgggagaaac aaaacaaaca caaagaccac caaggccacc
121 gacaccggaa ttggtgaaga agataccccc accccccccc aatggcgagg atgaaccaaa
181 gatagcgtat aaggtgggag aaggtgtgtc tgggctgccc gacttgacaa ccgtggcaca
241 acctgacgca cagaacacag cctacagtgt ccctccactt agccagagag aggtcggcga
301 agctaaagaa ccgttgcctg gctccattct ggaaatgtgg gatggtgaga tctaccacta
361 tgggctgtat gttgagcggg ggcatgtact gggggtgcac aaaccacccg ccgcaataag
421 ccttgccaaa attgaattaa caccgctgtc tctctactgg agagtggttt acactcccca
481 atatttgata gctccagaga cccttaagaa tttaaatgga gaggctttcc catacacggc
541 ctttgacaac aactgttatg ccttctgttg ttgggtttta gacctcaacg actcctggct
601 tagcagaaga atgatccaaa gaacaactgg attcttcaga ccgtatcagg actggaacag
661 aaaacccttg ccaaccatgg atgaaccaaa aatcaagaag gccgcgaatg ctgttctgtg
721 tgctctctcc tcactcttta ctaggcccat caaagatgtc attggaaagc tcaaaccact
781 gaacattatg aacatactgg caacttgtga ttggaccttt gcgggcatag tggaatccat
841 gatccttctt gctgagctct ttggggtgtt ctggacgccc ccagatgtgt ctgcaatgat
901 tgctccctta ctcggtgact acgagatgca aggccccgaa gacctggccg tggaacttgt
961 gcccgtggta atgggaggaa taggtttggt gttaggattc accaaggaaa agatcggcaa
1021 gatgctttca tcagctgcga ccacactcag ggcctgtaag gatctaggat cttatgggtt
1081 ggagatactc aaactggtca tgaagtggtt cttccccaag aaggaggagg ccaacgagtt
1141 agccatggtg agggccattg aggatgcagt tctggatttg gaggcaatag aaaacaacca
1201 catgaccact ctccttaagg acaaagacag cctggccaca tacatgagga ctcttgactt
1261 ggaagaagaa aaagcaagga aactgtcatc caaatcggcg tcacctgaca tcgtgggcac
1321 agtaaacgca ttattggcaa ggatagcagc cgccaggtca ctggtccaca aggctaagga
1381 ggagctctcg agcagacaga ggcctgttgt tgtaatgtta tcaggtaggc caggtatagg
1441 aaagacccat ctggccagag aactagccaa gaaggttgcg tcaacactgt caggcgacca
1501 aaggattgga ctggtaccta gaaatggcgt cgaccattgg gacgcctaca aaggagagcg
1561 ggtggttctg tgggatgact atggcatgag caaccccata caggacgcac tgaggctcca
1621 agaattggct gacacctgtc ccctgaccct aaattgtgac aggattgaaa acaaaggaaa
1681 agtgttcgac agcgacgcca taattataac aaccaacctc gcaaacccag caccactgga
1741 ttatgtcaac tttgaggctt gttctagacg catagacttc ttggtgtatg cagacgcacc
1801 tgacatcgag aaggctaagc gtgacttccc tggccaacca gatatgtgga aagaccatta
1861 cagatcagac ttctcacaca ttaaacttca gctggcacca cagggaggct ttgataagaa
1921 tggcaacacc ccacatggca aaggtgtggt taagtctctg acggttggtt ctctgatcgc
1981 cagggcttct ggcttgctcc atgagagaat ggatgaattt gagctccaag gctctgactt
2041 accaaccttc aatttcgacc gtaacaaagt cgccgccttc agacaattgg cagctgaaaa
2101 caaatatggt cttatggaca cactgagggt cggcaaccaa ctgaaaagtg tcaaaaccct
2161 ggatgagctg aagcaggcta taaagaacat caccatcaag aagtgccaga tagtgtacaa
2221 tggatgcacc tacaccatgg aatctgatgg gaggaacaag gttgtggttg aaaaggttca
2281 aaatgcaaca gtccaaacta acaatgaact tgcaggagca ctccaccacc tgaggtctgc
2341 aaggataagg tattatgtta aatgtttcca agaagctatt tactctctac tccaaattgc
2401 tggtgcagcc ttcgtcacca cacgcatcgt gaggcgcatg aacatctcaa acctctggtc
2461 gaagccaccc gtcgaagagg gtgatgagcc tgaagacaaa gaggggtgcc ccaagcccag
2521 ggatgaagat gacctcacta ttgactctaa agacattaaa gcagaaggga agaagggcaa
2581 gaacaaatct ggccggggca agaaacacac agctttctca tccaagggcc tcagtgatga
2641 agagtacgat gagtacaaga gaatcaggga ggagaggaat ggcaaatact caattgaaga
2701 atacctccag gacagggata gatactatga agagcttgcc attgctaagg ccactgagga
2761 agacttctgt gaagaggagg aaatcaaaat tcgccagagg atcttccggc ccaccaggaa
2821 gcaacggaga gatgaaagag ccacgcttgg gcttgtcaca ggatcggaaa tcagaaagag
2881 gaacccagat gacttcaaac caaaaggaaa attgtgggct gatgacaaca gaagtgtgga
2941 ctacaatgag aggatagatt ttgaggctcc cccgagtgtt tggtctagga tagtcaattt
3001 tggtacagga tggggattct gggtctctcc aagtctcttt ataacttcaa cacatgtcat
3061 accaaaagga atcaccgagg cctttggagt tcccattaac caaattcaaa ttcataaatc
3121 tggagagttt tgccgcttgc ggtttccaaa accaatcagg ccagacgtga gtggaatgat
3181 cttggaagag ggtgcccctg aaggcactgt tgtgtccatt ctcatcaaga ggacaacagg
3241 ggaactgatg cctctcgcag ttaggatggg aactcatgcc acaatgaaaa tccaaggtag
3301 aacggtgggt ggtcaaatgg gcatgcttct cactggctca aacgctaaaa gcatggacct
3361 aggcacaaca ccaggtgact gtgggtgccc atacatatac aaaaggggca atgacttcgt
3421 ggtcattggg gtgcacactg cagcagcccg tggaggcaac acggttatat gtgccacaca
3481 ggggagtgaa ggcgaagcca ccctcgaagg aggtgacaac aagggcacct attgtggagc
3541 ccccatcttg ggacctggca acgcaccaaa attaagcaca aaaacaaaat tctggagatc
3601 ttctaacgcg ccgcttcctc caggtaccta tgaaccagca taccttggtg gcaaagaccc
3661 gcgtgtgaag ggaggcccat ctctacaaca ggttatgaga gaccaactta aaccttttac
3721 agagcccaga gggaagccac caaaaccaag tgtcctagaa tcagcaaaga agaccatcat
3781 taatgttctg gagcaaacca ttgacccccc tgaaaagtgg tcatatgccc aagcttgtgc
3841 atccctcgac aagacaacct ccagtggata cccgcatcac gtccggaaga atgattattg
3901 gagtggtgaa tccttcacgg ggaaacttgc agaccaggcc tcaaaagcaa accttatgta
3961 tgaggaaggc aagcacatgc aaccagttta caccgcagca ctcaaagacg agctcgtgaa
4021 aactgacaaa atttatggca agatcaagaa aagactcctg tggggctctg acctatcaac
4081 catgattcga tgcgccaggg catttggtgg cctcatggat gagctcaaag caaattgtat
4141 catactccct gtcagagttg gtatgaacat gaatgaagat ggtcccataa tatttgaaaa
4201 gcactccagg tacaggtacc actatgatgc tgattactcc cgctgggatt ccacacaaca
4261 gcgggcagtg ctggaagcgg cacttgaaat catggtgaga ttttctgctg agccacagtt
4321 ggcacaaata gtggcagagg acctgctgtc accaagtgtg gttgatgtgg gcgatttcaa
4381 aattgttatc aatgaaggcc taccatctgg cgtgccttgc acttcacaat ggaattctat
4441 tgcccactgg ttactcacct tgtgtgccct gtctgaagtg acaggactag gccctgacat
4501 catacaagcc aactccatgt actctttcta tggtgatgat gagattgtga gcacagacat
4561 aaaattagac ccagagaaat tgactgcaaa actcaaagaa tatggtctta aacccacccg
4621 gcctgacaag actgaggggc cactggtaat tagtgaggac ctgaatgggt tgactttcct
4681 ccgccgaaca gtcacccgcg atccagctgg ttggtttgga aagttggacc aaaactccat
4741 cctcaggcag ctgtactgga caaggggacc taaccatgaa gaccccagtg agactatgat
4801 accacacgca cagagacctg tgcagctcat ggcactgcta ggagagtcct ccctacatgg
4861 accctcattt tacagcaagg ttagcaagct ggtcatatct gaacttaaag agggaggaat
4921 ggatttttat gtgcccagac aagagtcaat gttcaggtgg atgaggttct cagatctaag
4981 cacatgggag ggcgatcgca atctggctcc cagttttgtg aatgaagatg gcgtcgaatg
5041 acgccgctcc atctaatgat ggtgctgctg gtctcgtacc agagggcaat aacgagaccc
5101 ttcccctaga accagttgcg ggcgcagcta tagccgcacc cgtcactggc caaaacaata
5161 taattgaccc ctggattaga acaaattttg tgcaagcacc aaatggagag ttcacagtgt
5221 cacccagaaa ctctcctgga gaaattttac taaacctaga gttgggccct gatttgaacc
5281 cttatttggc tcatttgtca aggatgtaca atgggtacgc tggtggagtt gaagtccagg
5341 ttctcctggc agggaacgcg ttcactgccg ggaagatcct cttcgccgct gtcccgccaa
5401 atttcccagt ggaattctta agcccagccc agattacaat gctcccacat ataatagtag
5461 atgtcaggac tcttgaacca attatgatcc cattacctga tgttaggaat acattcttcc
5521 actataacaa ccagcccaac agccgcatga gattagtggc tatgctctat acccccctta
5581 gatctaatgg ctcaggtgat gatgttttca ctgtttcttg cagggttttg actagaccta
5641 ctcctgattt tgagttcact tatctagtgc caccctctgt tgaatctaaa actaagccct
5701 tttccttacc cattttaacc ctttctgagc tcacaaattc gaggttcccg gtccccattg
5761 attcgctttt caccgcccag aataatgtgt tgcaggtgca gtgtcaaaat ggcaggtgca
5821 cacttgacgg tgagctacaa ggtacaaccc agttgctccc atctggcatc tgtgcgttca
5881 gagggcgggt gacagcagaa actgacaacc ctgacaagtg gcacatgcaa ctgcaaaacc
5941 tcaatggcac aacgtatgac ccaactgatg atgtgccagc cccactgggt acacctgact
6001 tcaagggcgt cgtgtttggg atggcaagcc aaagaaatgt gggtaacgat gcgcccggct
6061 caaccagggc tcatgaggcg gtgatttcaa cctacagccc cagatttgtc cccaaattag
6121 gctctgtcaa tttcaaaagt aatgacgatg atttccaatt gcagccaaca agattcacac
6181 cagtgggcat taatgatgat ggcaaccacc cgttcagaca atgggaactg ccagactatt
6241 caggggtgct taccttgaat atgaaccttg cccccccggt tgctccaaat ttccctggtg
6301 aacaattatt attcttcaga tcttccgtgc catgttcagg aggttacaat caaggtatta
6361 tagattgtct tatcccccaa gaatggatcc aacacttcta ccaggaatca gcaccttctc
6421 agtcagacgt ggccctgatc aggtacgtca accccgacac gggtcgcaca ctgtttgagg
6481 caaaattgca cagatctggt tatatcactg tggctcactc tggagactat cctcttgttg
6541 tcccggctaa tggatacttt agatttgact cttgggtaaa ccagttttac tcactcgccc
6601 caatgggaac tgggaatggg cgaaggaggg ctcagtaatg gctggagctt tcattgcagg
6661 attggcgggt gacatgctca cgtcatccgt gggctccctg gtgaacgcag gggcaaacgc
6721 catcaaccaa aagatagact ttgaaaacaa caaacaactc cagtctgctt cctttcaaca
6781 tgataaagag atgctccaag cgcaggtaaa tgcaaccaag cagctgcaat ctgaaatgat
6841 agccctaaaa cagggggttt tggccgcagg cggcttttcc cccactgatg cagcgagggg
6901 ggccatcggt gcacccatga caaaggtgct tgactggtct ggcactcgat attgggctcc
6961 caattccaca aagacaactg gttattcggg gcaattcacc tcttcacctg tgcacatgcc
7021 cagcccgagt gctccacaat caaaacccgc aaagcccaga tctctaggtt cttcttcttc
7081 ttctagtagt gtttatagta tgtctaccca atcaacttct ctaacatctg gctcttctag
7141 taatgcttct tctgcttcta caaaattgac aaatttaagc tctggctcct ctcaaaacag
7201 gacagcagag tgggtgaacc aacagagaag tctcagccct ttcatgagtg gcgcactcaa
7261 tatctcacat gtcacgccac cttcaagtag ggcctccagt tctgggacgg tctcaaccgt
7321 gcccaaggaa gttttggact cctggacatc tgcattcaac acacgca
//