Typing tool
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Typing tool
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Complete norovirus genomes
| PQ336873 | GII.17 | |
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| GII.P17 |
ORF1: 1..5086
ORF2: 5067..6689
ORF3: 6689..7468
LOCUS PQ336873 7499 bp RNA linear VRL 22-OCT-2024
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/WT-NORO-1506/2019/UK
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PQ336873
VERSION PQ336873.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7499)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7499)
AUTHORS Roy,S., Williams,R.J., Tutill,H.J., Wong,S., Celma,C. and Breuer,J.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2024) Division of viral diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7499
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/WT-NORO-1506/2019/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Dec-2019"
/note="genotype: GII.17[P17]"
gene <1..5086
/gene="ORF1"
CDS <1..5086
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XGX96799.1"
/translation="SAAVAGKNNNNDKEKSSSDSLFANMSVTFKKALGARSKQPPPGE
TKQIQKPPRPPTPELVKRIPPPPPNGEDEPGIVYKVGEGVSGLPDLTTVVQPDAQNTA
YSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAKIE
ITPLSLYWRVVYTPQYLIDPGTLKNLSGETFPYTAFDNNCYAFCCWVLDLNDSWLSRR
MIQRTTGFFKPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDIIGKLRPLN
ILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAVEL
VPVVMGGIGLVLGFTKEKIGRMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKEEA
NELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASP
DIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVA
STLSGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLN
CDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDF
PGQPDMWKDHFRPDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGLLH
ERMDEFELQGSDLPTFNFDRNKVVAFRQLAAENKYGLMDTLRVGNQLKSVKTMDELKQ
AIKNISIKKCQIVYNGCTYTMESDGRGKVVVEKVQNATVQTNNELVGALHHLRSARIR
YYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPIEEGDEPEDKGGCPKPRD
EDDLTIDSRDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIE
EYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEI
RKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFIT
STHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSI
LIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPY
MYKRGNDLVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAP
KLSTKTKFWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPP
NPNVLESAKKTIINVLEQTIDPPQKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESF
TGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIR
CARAFGGLMDEFKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQR
AVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCTSQWNS
IAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLK
PTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDP
SETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRW
MRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..976
/gene="ORF1"
/product="p48"
mat_peptide 977..2074
/gene="ORF1"
/product="NTPase"
mat_peptide 2075..2611
/gene="ORF1"
/product="p22"
mat_peptide 2612..3010
/gene="ORF1"
/product="VPg"
mat_peptide 3011..3553
/gene="ORF1"
/product="Pro"
mat_peptide 3554..5083
/gene="ORF1"
/product="RdRp"
gene 5067..6689
/gene="ORF2"
CDS 5067..6689
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGX96800.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQSNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAQINQRDRWHMQLQNLNGATYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGNDAPGSTRAQQAWISTYSPQFVPKLGSVNLRISDNDDFQFQPTKFTPVGVN
DDDDGHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6689..7468
/gene="ORF3"
CDS 6689..7468
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGX96801.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQFQSA
SFQHDKEMLQAQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPNAPQSKPAKPRSLAPSSSSSSVYSMYTQST
HLTSGSSSNASSASTKSTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 ttccgctgcc gttgctggca aaaacaacaa caacgacaag gaaaaatctt caagcgacag
61 cttgtttgct aacatgtctg ttacttttaa gaaagccctc ggggcgcggt ctaaacaacc
121 gcccccggga gaaacaaaac aaatacaaaa accaccaagg ccaccgacac cggaattggt
181 gaagagaata cctccacccc cacccaatgg cgaggatgaa ccagggatag tgtacaaggt
241 gggagagggt gtgtctgggc tgcccgacct aacaacagtg gtgcaacctg acgcacaaaa
301 cacagcttat agtgttcccc cacttagtca gagagaagtc ggcgaagcta aagaaccgct
361 gcctggctcc attctggaaa tgtgggatgg tgagatctac cactatgggc tgtatgttga
421 gcgggggcat gtgctcggag tacacaaacc acctgctgca ataagccttg ccaaaattga
481 aataacaccg ctgtctctct actggagagt ggtctacact ccccagtatt tgatagatcc
541 aggaactctt aagaacttga gtggagagac tttcccatac acggcctttg acaacaactg
601 ctatgccttc tgttgttggg tcctagacct caacgactcc tggcttagca ggagaatgat
661 ccaaagaaca actggatttt tcaaacctta tcaggattgg aacagaaaac ccttaccaac
721 catggatgaa ccgaaaatca agaaggccgc gaatgctgtc ctatgcgctc tctcctcact
781 cttcactagg cccattaagg acatcattgg aaagcttagg ccactgaaca ttcttaatat
841 actggcaacc tgcgattgga cttttgcagg catagtggaa tccttgatcc ttcttgctga
901 actctttggg gtgttctgga cacccccaga cgtgtctgcg atgattgctc ccttactcgg
961 tgactacgag atgcaaggcc ccgaagacct ggccgtggaa cttgtgcccg tggtgatggg
1021 aggaataggt ttggtgttag gattcaccaa agaaaagatc ggcaggatgc tttcatcagc
1081 tgcgaccaca cttagggcct gcaaggatct aggatcttat ggattggaga tactcaaatt
1141 ggtcatgaag tggttcttcc ccaagaagga ggaggctaac gaactagcca tggtgagggc
1201 cattgaggat gcagtcttgg atttggaggc aatagaaaac aatcacatga ccacccttct
1261 caaggataaa gacagcctgg ccacatacat gaggactctt gacttggaag aagagaaagc
1321 aaggaaactg tcaaccaaat cggcgtcacc tgacatcgtg ggcacaataa atgctttatt
1381 ggctaggata gcagccgcca ggtcactggt ccacaaggct aaggaggagc tctcgagcag
1441 acagagacct gttgtcgtaa tgatatcagg tagaccaggt ataggaaaga cccatctggc
1501 cagagagcta gccaagaaag ttgcgtcaac actgtcaggc gaccaaagga ttggactggt
1561 gcctagaaat ggcgtcgacc attgggacgc ctacaaggga gaaagggtgg ttctgtggga
1621 tgattatggt atgagcaacc ctatacagga cgcactgagg ctccaagagt tggcagacac
1681 ctgtcccctg accctaaatt gtgataggat tgaaaacaaa ggaaaagtgt tcgacagtga
1741 tgccataatt ataacaacca accttgcgaa cccagcacca ctggactatg tcaactttga
1801 ggcctgctct aggcgcatag acttcttggt gtatgcagac gcacctgaca ttgagaaggc
1861 taagcgtgac ttccctggcc aaccggatat gtggaaagac catttcagac cagacttctc
1921 gcacattaaa cttcagctgg caccacaggg aggttttgac aaaaatggca acaccccaca
1981 tggcaaaggt gtggtgaagt ccctgacgat tggttctctg atcgccaggg cctccggctt
2041 gctccacgag agaatggatg aattcgagct ccaaggctct gacctgccaa ccttcaactt
2101 tgaccgcaac aaagtcgtcg ccttcagaca attagcagct gaaaacaaat atggtcttat
2161 ggacacactg agggtcggca accaactgaa aagtgttaag accatggatg agctgaagca
2221 ggccataaag aacatcagta tcaagaagtg tcagatagtg tataatggat gcacctatac
2281 catggaatct gatgggaggg gcaaggttgt ggttgaaaag gtgcaaaacg caacagttca
2341 aaccaacaat gaacttgtag gggcgctcca ccacctgaga tctgcaagga taagatacta
2401 tgttaaatgt ttccaagaag ccatttactc tctactccaa attgctggcg cagccttcgt
2461 cacctcacgc atcgtgaggc gcatgaacat atcaaacctc tggtcgaagc cacccatcga
2521 ggagggtgat gagcctgaag acaaaggagg atgccccaag cccagggatg aagatgacct
2581 cactattgac tctagagaca ttaaagtgga agggaagaag ggcaagaaca agtctggccg
2641 gggcaagaaa cacacagcct tctcttccaa gggcctcagt gatgaagagt acgatgagta
2701 caagagaatc agagaggaga ggaatggcaa atactcaata gaggagtacc tccaagatag
2761 ggacaggtac tatgaagagc ttgccattgc taaggccact gaggaggact tctgtgagga
2821 ggaggagatc aaaatccgcc agagaatctt ccgacccacc aggaagcagc ggaaagagga
2881 aagggccacg cttgggcttg tcacaggatc ggaaatcaga aaaaggaatc cagatgactt
2941 taagccaaaa ggaaaattgt gggctgatga caacaggagc gtggattaca atgagaggat
3001 agattttgag gctcccccga gtgtttggtc taggatagtc aactttggca caggctgggg
3061 attctgggtt tctccaagtc tctttataac ttcaacacac gtcataccaa aaggaatcac
3121 tgaggccttt ggagtgccca taaaccaaat ccaaattcac aaatctggag aattttgccg
3181 cttgcggttt ccaaagccaa ttagaccaga cgtgagtggg atgatcttgg aagagggcgc
3241 ccctgaaggc actgttgtgt ccattctcat caaaaggaca acaggggagc tgatgcctct
3301 tgcagtcaga atggggactc atgccacaat gaaaatccaa ggtagaacgg taggtggtca
3361 gatgggtatg cttctcactg gctcaaatgc taaaagcatg gatctaggca caacgccagg
3421 tgactgcgga tgtccataca tgtacaaaag gggcaatgac cttgtggtca ttggggtgca
3481 cactgcagca gctcgtggag gcaacacggt catatgtgcc acacagggaa gtgaaggtga
3541 agccactctt gaaggaggtg acaacaaggg tacctattgt ggagccccca ttttgggacc
3601 tggcaatgca ccaaagttga gcacaaagac aaaattctgg agatcctcta acgcaccgct
3661 ccccccaggt acttatgaac cagcatacct tggtgggaga gacccgcgcg tgaagggagg
3721 cccatctctg caacaagtta tgagagacca acttaaacct tttacagagc ccagagggaa
3781 gccaccaaac ccaaatgtct tagagtcagc aaagaagact atcatcaatg ttctggaaca
3841 aaccattgac ccccctcaaa agtggtcata tgcccaagct tgtgcatccc tcgacaagac
3901 aacctccagt ggatacccgc accacgtccg gaagaatgac tattggagtg gtgagtcctt
3961 cacaggaaaa cttgctgatc aggcttcaaa agcaaatctc atgtatgagg aaggcaagca
4021 catgcaacca gtttacaccg cagcactcaa agacgagctc gtgaaaactg acaaaattta
4081 tggcaaaatc aagaaaagac tcctatgggg ctctgacctc tccacaatga ttcgatgcgc
4141 cagagcattt ggtggtctca tggatgaatt caaagcaaat tgtattacac tccctataag
4201 agttggtatg aatatgaatg aagatggtcc cataatattt gagaagcact ccaggtacag
4261 gtaccactat gatgctgatt actcccgctg ggactccaca caacagcggg cagtgctgga
4321 agcggcactt gaaatcatgg tgagattttc tgctgagcca cagctggcac aaatagtggc
4381 agaggacctg ctgtcaccaa gtgtggttga tgtgggcgat tttaaaatcg ctatcaatga
4441 aggcctacca tctggcgtgc cttgcacctc acaatggaat tctattgccc actggttact
4501 caccttgtgt gccctttctg aagtgacagg attaggtcct gacatcatac aagctaactc
4561 catgtactct ttctatggtg atgatgagat tgtgagcaca gacataaaat tggacccaga
4621 gaaattgacc gcaaagctca aagaatatgg ccttaaaccc actcggcccg acaaaactga
4681 ggggccgttg gtgattagtg aggacctgaa tgggttgact ttcctccgcc gaacagtcac
4741 ccgtgatcca gcaggttggt ttggaaagtt ggaccaaaat tccatcctca ggcagttgta
4801 ctggacaaga ggacccaacc atgaagaccc cagtgagacc atgataccac acgcacaaag
4861 acctgtgcag ctcatggcac tactaggaga atcctcccta catggaccct cattttacag
4921 caaggttagc aaattagtca tatctgaact taaagaggga ggaatggatt tttatgtgcc
4981 tagacaagag tcaatgttca gatggatgag gttctcagat ctaagcacat gggagggcga
5041 tcgcaatctg gctcccagtt ttgtgaatga agatggcgtc gaatgacgcc gctccatcta
5101 atgatggtgc tgctggtctc gtaccagagg gcaacaacga gacccttccc ctagaaccag
5161 ttgcgggcgc agctatagcc gcacccgtca ctggccaaaa taacataatt gacccctgga
5221 ttagaacaaa ttttgtgcaa gcaccaaatg gagagttcac agtgtcaccc agaaactctc
5281 ctggagaaat tttattaaac ttagagttgg gccctgattt gaacccttat ttggcccact
5341 tgtcaaggat gtacaatggg tatgctggtg gagtggaagt tcaggttctc ctggcaggga
5401 acgcgttcac tgccgggaag atcctcttcg ccgccgtccc gccaaatttc ccagtggaat
5461 tcttaagccc agcccagatc acaatgctcc cacatttaat agtagatgtt aggactcttg
5521 aaccaattat gatcccactc cctgatgtta ggaatacatt ctttcattat agtaaccagt
5581 ccaacagccg catgagatta gtggctatgc tctatacccc actcagatct aatggctcag
5641 gtgatgatgt ctttactgtc tcttgcaggg ttttgactag gcctactcct gattttgagt
5701 tcacttattt agtgccacct tctgttgagt ctaaaactaa gcctttttcc ttacctattt
5761 taaccctttc tgagctcaca aattcgaggt tcccagtccc catcgattcg cttttcaccg
5821 cccagaataa tgtgttgcag gtgcagtgtc aaaatggcag gtgcacactt gatggtgagt
5881 tacaaggcac aacccagttg ctcccatctg gcatctgtgc attcagagga cgggtgacag
5941 cacaaattaa tcaacgtgac aggtggcaca tgcaactgca aaacctcaat ggtgcaacat
6001 atgacccaac tgatgatgtg ccagccccgc tgggtacacc tgacttcaag ggcgtcgtgt
6061 ttgggatggt aagccaaaga aatgtgggta atgatgcgcc tggctcaacc agagcccaac
6121 aggcgtggat ttcaacctat agcccccaat ttgtccccaa attaggttct gtcaatctta
6181 gaattagtga taatgatgat ttccaattcc aaccgacaaa attcacacca gtgggcgtca
6241 atgatgacga tgatggccac ccgttcagac aatgggaact accaaactat tcaggggagc
6301 ttaccttgaa tatgaatctt gcccccccag ttgctccaaa ttttcctggt gaacaattgt
6361 tgttcttcag atctttcgtg ccatgctcag gaggttacaa ccaaggtatt atagattgtc
6421 ttattcccca agaatggatc caacacttct atcaggaatc agcaccctcc cagtcagacg
6481 tggccctaat caggtatgtc aaccccgata cgggacgtac actgtttgaa gcaaagttgc
6541 acagatctgg ttacattact gtggctcact ctggagacta tcctcttgtt gttccggcta
6601 atggacactt tagattcgat tcttgggtaa atcagtttta ctcactcgcc ccaatgggaa
6661 ctgggaatgg gcgaaggagg gctcagtaat ggctggggct ttcattgcag gattggcagg
6721 cgacatgctc acgtcatctg tgggctccct tgtgaatgca ggggcaaacg ccatcaacca
6781 aaagatagac tttgaaaaca acaaacaatt ccagtctgct tcctttcagc atgataaaga
6841 gatgctccaa gcgcaggtga gggcaaccaa gcagctgcaa tctgaaatga tagctctaaa
6901 acagggggtt ttggccgcag gcggcttttc ccccactgat gcagcaaggg gatccatcgg
6961 tgcacccatg acaaaggtgc ttgactggtc tggcactcga tactgggcgc ccaattccac
7021 aaagacaact ggctattcgg gacaattcac ctcttcacct gtgcatatgt ctagcccaaa
7081 tgctccacaa tcaaaacctg caaagcctag gtctctagct ccttcctctt cttctagcag
7141 tgtctatagt atgtatactc aatctactca tttaacatct ggctcttcta gtaatgcttc
7201 ttctgcctcc acaaaatcga caaatttaag ctctggctcc tctcaaaata gaacagcaga
7261 gtgggtaaat caacagagaa gtcttagccc tttcatgagt ggtgcactta acatctcaca
7321 tgtcacgcca ccctcaagta gggcttccag ttctggaacg gtctcgaccg tgcccaagga
7381 agttttggac tcctggacgt ctgcgtttaa cacacacaga cagccgctct tcgcacacct
7441 cagagtgagg ggggagtcac gtgtttagtg aaaagaaata attggctata atgtgattt
//