Typing tool
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Typing tool
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Complete norovirus genomes
| PQ336871 | GII.17 | |
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| GII.P17 |
ORF1: 1..5086
ORF2: 5067..6689
ORF3: 6689..7468
LOCUS PQ336871 7499 bp RNA linear VRL 22-OCT-2024
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/WT-NORO-2324/2022/UK
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PQ336871
VERSION PQ336871.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7499)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7499)
AUTHORS Roy,S., Williams,R.J., Tutill,H.J., Wong,S., Celma,C. and Breuer,J.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2024) Division of viral diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7499
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/WT-NORO-2324/2022/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="May-2022"
/note="genotype: GII.17[P17]"
gene <1..5086
/gene="ORF1"
CDS <1..5086
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XGX96793.1"
/translation="SAAVAGKNNNNDKEKSSSDSLFANMSVTFKKALGARSKQPPPGE
TKQIQKPPRPPTPELVKRIPPPPPNGEDEPGIVYKVGEGVSGLPDLTTVVQPDAQNTA
YSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAKIE
ITPLSLYWRVVYTPQYLIDPGTLKNLSGETFPYTAFDNNCYAFCCWVLDLNDSWLSRR
MIQRTTGFFKPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDIIGKLRPLN
ILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAVEL
VPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKEEA
NELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASP
DIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVA
STLSGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLN
CDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDF
PGQPDMWKDHFRPDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGLLH
ERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQ
AIKNISIKKCQIVYNGCTYTMESDGRGKVVVEKVQNATVQTNNELVGALHHLRSARIR
YYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPIEEGDEPEDRGGCPKPRD
EDDLTIDSRDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIE
EYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEI
RKRNPDDFKPKGRLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFIT
STHVIPKGITEAFGVPTNQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSI
LIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKGMDLGTTPGDCGCPY
IYKRGNDLVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAP
KLSTKTKFWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPP
NPNVLESAKKTIINVLEQTIDPPQKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESF
TGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIR
CARAFGGLMDEFKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQR
AVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCTSQWNS
IAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLK
PTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDP
SETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRW
MRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..976
/gene="ORF1"
/product="p48"
mat_peptide 977..2074
/gene="ORF1"
/product="NTPase"
mat_peptide 2075..2611
/gene="ORF1"
/product="p22"
mat_peptide 2612..3010
/gene="ORF1"
/product="VPg"
mat_peptide 3011..3553
/gene="ORF1"
/product="Pro"
mat_peptide 3554..5083
/gene="ORF1"
/product="RdRp"
gene 5067..6689
/gene="ORF2"
CDS 5067..6689
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGX96794.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPTGICAFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGNDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISNNDDFQFQPTKFTPVGVN
DDDDDHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6689..7468
/gene="ORF3"
CDS 6689..7468
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGX96795.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPNAPQSKPAKPRSLAPSSSSSSVYSMYTQST
HLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 ttccgctgcc gttgctggca aaaacaacaa caacgacaag gaaaaatctt caagtgacag
61 cttgtttgct aacatgtctg tcacttttaa gaaagccctc ggggcgcggt ctaaacaacc
121 gcccccggga gaaacaaaac aaatacaaaa accaccaagg ccaccgacac cggaattggt
181 gaagagaata cctccacccc cacccaatgg cgaggatgaa ccagggatag tgtacaaggt
241 gggagagggc gtgtctgggc tgcccgacct aacaactgtg gtacaacctg acgcacaaaa
301 cacagcttat agtgttcccc cacttagcca gagagaagtc ggcgaagcta aagaaccgct
361 gcctggctcc atcctggaaa tgtgggatgg tgagatctac cactatgggc tgtatgttga
421 gcgggggcat gtgctcggag tacacaaacc acctgctgca ataagccttg ccaaaattga
481 aataacaccg ctgtctctct actggagagt ggtctacact ccccagtatt tgatagatcc
541 aggaactctt aagaacttga gtggagagac tttcccatac acggcctttg acaacaactg
601 ttatgccttc tgttgttggg tcctagacct caacgactcc tggcttagca ggagaatgat
661 ccaaagaaca actggattct tcaaacctta tcaggattgg aacagaaaac ccttaccaac
721 catggatgaa ccgaaaatca agaaggccgc gaatgctgtc ctatgcgctc tctcctcact
781 cttcactaga cccattaagg acatcattgg aaagcttaga ccactgaaca ttcttaatat
841 actggcaacc tgcgattgga cttttgcagg catagtggaa tccttgatcc ttcttgctga
901 actctttggg gtgttctgga cacccccaga tgtgtctgcg atgattgctc ccttactcgg
961 tgactacgag atgcaaggcc ccgaagacct ggccgtggaa cttgtacccg tggtgatggg
1021 aggaataggt ttggtgttag gattcaccaa agaaaagatc ggcaagatgc tttcatcagc
1081 tgcgaccaca ctcagggcct gcaaggatct aggatcttat ggattggaga tactcaaatt
1141 ggtcatgaag tggttcttcc ccaagaagga ggaggctaac gaactagcca tggtgagggc
1201 cattgaggat gcagtcctgg atttggaggc aatagaaaac aatcacatga ccacccttct
1261 caaggataaa gacagcctgg ccacatacat gaggactctt gacttggaag aagagaaagc
1321 aaggaaactg tcaaccaaat cggcgtcacc tgacatcgtg ggtacaataa acgcattgtt
1381 ggctaggata gcagccgcca ggtcactggt ccacaaggct aaggaggagc tctcgagcag
1441 acagagacct gttgttgtaa tgatatcagg cagaccaggt ataggaaaga cccatctggc
1501 cagagagcta gccaagaaag ttgcgtcaac actgtcaggc gaccaaagga ttggactggt
1561 acctaggaat ggcgtcgacc attgggacgc ctacaaggga gaaagggtgg tcctgtggga
1621 tgattatggt atgagcaacc ctatacagga cgcactgagg ctccaagaat tggctgacac
1681 ctgtcctctg accctaaatt gtgataggat tgaaaacaaa ggaaaagtgt tcgacagtga
1741 tgccataatt ataacaacca accttgcaaa cccagcacca ctagactatg tcaactttga
1801 ggcctgctct agacgcatag acttcttggt gtatgcagac gcacctgaca ttgagaaggc
1861 taagcgtgac ttccctggcc aaccagatat gtggaaagac catttcagac cagacttctc
1921 acacattaaa cttcagctgg caccacaggg aggttttgac aaaaatggca acaccccaca
1981 tggcaaaggt gtggtaaagt ccctgacgat tggttctctg atcgccaggg cctccggctt
2041 gctccacgag agaatggatg aattcgagct ccaaggctct gacctgccaa ccttcaattt
2101 tgaccgcaac aaagtcgccg ccttcagaca attagcagct gaaaacaaat atggtcttat
2161 ggacacattg agggtcggca accaactgaa aagtgttaag accctggatg agctgaagca
2221 ggccataaag aacatcagca tcaagaagtg tcagatagtg tataatggat gcacctatac
2281 catggaatct gatgggaggg gcaaggttgt ggttgaaaag gtacaaaacg caacagttca
2341 aaccaacaat gaacttgtag gggcgctcca ccacctgaga tctgcaagga taagatacta
2401 tgttaaatgt ttccaagaag ccatttactc tctactccaa attgctggtg cagcctttgt
2461 cacctcacgc atcgtgaggc gcatgaacat atcaaacctc tggtcgaagc cacccatcga
2521 ggagggtgat gagcctgaag acagaggagg atgccccaag cccagggatg aagatgacct
2581 cactattgac tctagagaca ttaaagtgga agggaagaag ggcaagaaca agtctggccg
2641 aggcaagaaa cacacagcct tctcttccaa gggcctcagt gatgaagagt acgatgagta
2701 caagagaatc agagaggaga ggaatggcaa atactcaata gaggaatacc tccaagatag
2761 ggacagatac tatgaagagc ttgccattgc taaggccact gaggaggact tctgtgagga
2821 ggaggagatc aaaatccgcc agagaatctt ccgacccacc aggaagcagc ggaaagagga
2881 aagggccacg cttgggcttg tcacaggatc ggaaatcaga aagaggaatc cagatgactt
2941 taaaccaaaa ggaagattgt gggctgatga caacaggagc gtggattaca atgagaggat
3001 agattttgag gctcccccga gcgtttggtc taggatagtc aactttggca caggttgggg
3061 attctgggtt tctccaagtc tctttataac ttcaacacac gtcataccaa aaggaatcac
3121 tgaggccttt ggagtgccca caaaccaaat ccaaattcac aaatctggag aattttgccg
3181 cttgcggttt ccaaagccaa ttagaccaga cgtgagtggg atgatcttgg aagagggcgc
3241 ccctgaaggc actgttgtgt ctattctcat caaaaggaca acaggggagc tgatgcctct
3301 tgcagtcaga atggggactc atgccacaat gaaaatccaa ggtagaacgg tgggtggtca
3361 gatgggtatg cttctcactg gctcaaatgc taaaggcatg gatctaggca caacgccagg
3421 tgactgcgga tgtccataca tatacaaaag gggcaatgac cttgtagtca ttggggtgca
3481 cactgcagca gctcgtggag gcaacacggt catatgtgcc acacagggaa gtgaaggtga
3541 agccactctt gaaggaggtg acaacaaggg tacctattgt ggagccccca ttttgggacc
3601 tggcaatgca ccaaaattga gcacaaagac aaaattctgg agatcctcta acgcaccgct
3661 tcccccaggt acttatgaac cagcatacct tggtgggaga gacccgcgcg tgaaaggagg
3721 cccatctctg caacaagtta tgagagacca acttaaacct tttacagagc ccagagggaa
3781 gccaccaaac ccaaatgtct tagagtcagc aaagaagact atcatcaatg ttctggaaca
3841 aaccattgac ccccctcaaa agtggtcata tgcccaagct tgtgcatccc tcgacaagac
3901 aacctccagt ggatacccgc accacgtccg gaagaatgac tattggagtg gtgaatcctt
3961 cacaggaaaa cttgcagatc aggcttcaaa agcaaatctc atgtatgagg aaggcaagca
4021 catgcaacca gtttacaccg cagcactcaa agacgagctc gtgaaaactg acaaaattta
4081 tggcaaaatc aagaaaagac tcctgtgggg ttctgacctc tccacaatga ttcgatgcgc
4141 cagagcattt ggtggtctca tggatgaatt caaagcaaat tgcattacac tccctatcag
4201 agttggtatg aatatgaatg aagatggtcc cataatattt gagaaacact ccaggtacag
4261 gtaccactat gatgctgatt actcccgctg ggactccaca caacagcggg cagtgctgga
4321 agcggcactt gaaatcatgg tgaggttttc tgctgagcca cagctggcac aaatagtggc
4381 agaggacctg ctgtcaccaa gtgtggttga tgtgggcgat ttcaaaatcg ctatcaatga
4441 aggcctacca tctggcgtgc cttgcacctc acaatggaat tctattgccc actggttact
4501 taccttgtgt gccctttctg aagtgacagg attaggtcct gacatcatac aagctaactc
4561 catgtactct ttctatggtg atgatgagat tgtgagcaca gacataaaat tggacccaga
4621 gaaattgacc gcaaagctca aagaatatgg ccttaaaccc actcggcccg acaaaactga
4681 ggggccgttg gtgattagtg aggacctgaa tgggttgact ttcctccgcc gaacagtcac
4741 ccgtgatcca gcaggctggt ttggaaagtt ggaccaaaac tccatcctca ggcagttgta
4801 ctggacaaga ggacccaacc atgaagaccc cagtgagacc atgataccac acgcacaaag
4861 acctgtgcag ctcatggcac tactaggaga atcctcccta catggaccct cattttacag
4921 caaggttagc aaattagtca tatctgaact taaagaggga ggaatggatt tttatgtgcc
4981 cagacaagag tcaatgttca gatggatgag gttctcagat ctaagcacat gggagggcga
5041 tcgcaatctg gctcccagtt ttgtgaatga agatggcgtc gaatgacgcc gctccatcta
5101 atgatggtgc tgctggtctc gtaccagagg gcaacaacga gacccttccc ctagaaccag
5161 ttgcgggcgc agctatagcc gcacccgtca ctggccaaaa taatataatt gacccctgga
5221 ttagaacaaa ttttgtgcaa gcaccaaatg gagagttcac agtgtcaccc agaaactctc
5281 ctggagaaat tttattaaat ttagagttgg gccctgattt gaacccttat ttggctcatt
5341 tgtcaaggat gtacaatggg tatgctggtg gagtggaagt tcaggttctc ctggcaggga
5401 acgcgttcac tgccggaaag atcctcttcg ccgccgtccc gccaaatttc ccagtggaat
5461 tcttaagccc agcccagatc acaatgctcc cacatttaat agtagatgtt aggactcttg
5521 aaccaattat gatcccactc cctgatgtta ggaatacatt cttccattat agtaaccagc
5581 ctaacagccg catgagatta gtggctatgc tctacacccc actcagatct aatggctcag
5641 gtgatgatgt ctttactgtc tcttgcaggg ttttgactag gcctactcct gattttgagt
5701 tcacttattt agtgccacct tctgttgaat ctaaaactaa gcctttttcc ttacctattt
5761 taaccctttc tgagctcaca aattcgaggt ttccagtccc catcgattcg cttttcaccg
5821 cccagaataa tgtgttgcag gtgcagtgtc aaaatggcag gtgtacactt gatggtgagt
5881 tacaaggcac aacccagttg ctcccaactg gcatctgtgc attcagagga cgggtgacag
5941 cacaaattaa ccaacgtgac aggtggcaca tgcaactgca aaacctcaat ggtacaacat
6001 atgacccaac tgatgatgtg ccagccccgc tgggtacacc tgacttcaag ggcgtcgtgt
6061 ttgggatggt aagccaaaga aatgtgggta atgatgcgcc tggctcaacc agagcccaac
6121 aggcgtgggt ttcaacctat agcccccaat ttgtccccaa attaggttct gtcaatctta
6181 gaattagtaa taatgatgat ttccaattcc agccgacaaa attcacacca gtgggcgtca
6241 atgatgacga tgatgaccac ccgttcagac agtgggaact accaaactat tcaggggagc
6301 ttaccttgaa tatgaatctt gcccccccag ttgctccaaa ttttcctggt gaacaattgt
6361 tattcttcag gtctttcgtg ccatgctcgg gaggttacaa ccaaggtatt atagattgtc
6421 ttatccccca agaatggatc caacacttct atcaggaatc agcaccatcc cagtcagacg
6481 tggccctaat caggtatgtc aaccccgata cgggacgtac actgtttgaa gcaaaattgc
6541 acagatctgg ttacattact gtggctcact ctggagacta tcctcttgtt gttccggcta
6601 atggacactt tagatttgat tcttgggtaa atcagtttta ctcactcgcc ccaatgggaa
6661 ctgggaatgg gcgaaggagg gctcagtaat ggctggggct ttcattgcag gattggcagg
6721 cgacatgctc acgtcatctg tgggctccct tgtgaacgca ggggcaaacg ccatcaacca
6781 aaagatagac tttgaaaaca acaaacaact ccagtctgct tcctttcagc atgataaaga
6841 gatgctccaa gcgcaggtga gggcaaccaa gcagctgcaa tctgaaatga tagccctaaa
6901 acagggggtt ttggccgcag gcggcttttc ccccactgat gcagcaaggg gatccattgg
6961 tgcacccatg acaaaggtgc ttgactggtc tggcactcga tactgggcgc ccaattccac
7021 aaagacaact ggctattcgg gacaatttac ctcttcacct gtgcatatgt ctagcccaaa
7081 tgctccacaa tcaaaacctg caaagcctag gtctctagct ccttcctctt cttctagcag
7141 tgtctatagt atgtatactc aatctactca tttgacatct ggctcttcta gtaatgcttc
7201 ttctgcctct acaaaattga caaatttaag ctctggctcc tctcaaaaca gaacagcaga
7261 gtgggtaaat caacagagaa gtcttagccc ttttatgagt ggcgcactta acatctcaca
7321 tgtcacgcca ccctcaagta gggcttccag ttctgggacg gtctcgaccg tgcccaagga
7381 agttttggac tcctggacgt ctgcgtttaa cacacacaga cagccgctct tcgcacacct
7441 cagagtgagg ggggagtcac gtgtttagtg aaaagaaata attggctata atgtgattt
//