Typing tool
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Typing tool
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Complete norovirus genomes
| PQ336869 | GII.17 | |
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| GII.P17 |
ORF1: 1..5086
ORF2: 5067..6689
ORF3: 6689..7468
LOCUS PQ336869 7499 bp RNA linear VRL 22-OCT-2024
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/WT-NORO-1984/2022/UK
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PQ336869
VERSION PQ336869.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7499)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7499)
AUTHORS Roy,S., Williams,R.J., Tutill,H.J., Wong,S., Celma,C. and Breuer,J.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2024) Division of viral diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7499
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/WT-NORO-1984/2022/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Jun-2021"
/note="genotype: GII.17[P17]"
gene <1..5086
/gene="ORF1"
CDS <1..5086
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XGX96787.1"
/translation="SAAVAGKNNNNDKEKSSSDSLFANMSVTFKKALGARPKQPPPGE
TKQIQKPPRPPTPELVKRIPPPPPNGEDEPGIVYKAGEGVSGLPDLTTVAQPDAQNTA
YSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAKIE
ITPLSLYWRVVYTPQYLIDPGTLKNLSGETFPYTAFDNNCYAFCCWVLDLNDSWLSRR
MIQRTTGFFKPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDIIGKLRPLN
ILNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAVEL
VPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKEEA
NELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASP
DIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVA
STLSGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLN
CDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDF
PGQPDMWKDHFRPDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGLLH
ERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQ
AIKNISIKKCQIVYNGCTYTMESDGRGKVVVEKVQNATVQTNNELVGALHHLRSARIR
YYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPIEEGDEPEDRGGCPKPRN
EDDLTIDSRDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIE
EYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEI
RKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFIT
STHVIPKGITEAFGVSINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSI
LIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKGMDLGTTPGDCGCPY
IYKRGNDLVVIGVHTAAARGGNTVICATQGSEGEATLEGDDNKGTYCGAPILGPGNAP
KLSTKTKFWRSSNAPLPPGTYEPTYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPP
NPNVLESAKKTIINVLEQTIDPPQKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESF
TGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIR
CARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQR
AVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCTSQWNS
IAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLK
PTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDP
SETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRW
MRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..976
/gene="ORF1"
/product="p48"
mat_peptide 977..2074
/gene="ORF1"
/product="NTPase"
mat_peptide 2075..2611
/gene="ORF1"
/product="p22"
mat_peptide 2612..3010
/gene="ORF1"
/product="VPg"
mat_peptide 3011..3553
/gene="ORF1"
/product="Pro"
mat_peptide 3554..5083
/gene="ORF1"
/product="RdRp"
gene 5067..6689
/gene="ORF2"
CDS 5067..6689
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGX96788.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPTGICAFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGNDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISNNDDFQFQPTKFTPVGIN
DDDDDHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6689..7468
/gene="ORF3"
CDS 6689..7468
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGX96789.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGASAINQKVDFENNKQLQSA
SFQHDKEMLQAQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPNAPQSKPAKTRSLVPSSSSSSVYSMYTQST
HLTSGSSSNASSASTKLTNLSSGPSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 ttccgctgcc gttgctggca aaaacaacaa caacgacaag gaaaaatctt caagtgacag
61 cttgtttgct aatatgtctg tcacttttaa gaaagccctc ggggcgcggc ctaaacaacc
121 gcccccggga gaaacaaaac aaatacaaaa accaccaagg ccaccgacac cggaattggt
181 gaagagaata cctccacccc cacccaatgg cgaggatgaa ccagggatag tgtacaaggc
241 gggagagggt gtgtctgggc tgcccgacct aacaactgtg gcacaacctg acgcacaaaa
301 cacagcttac agtgttcccc cacttagcca gagagaagtc ggcgaagcta aagaaccgct
361 gcctggctcc attctggaga tgtgggatgg tgagatctac cactatgggc tgtatgttga
421 gcgggggcac gtgctcggag tacacaaacc acctgctgca ataagccttg ccaaaattga
481 aataacaccg ctgtctctct actggagagt ggtctacact ccccagtatt tgatagatcc
541 aggaactctt aagaacttga gtggagagac tttcccatac acggcctttg acaataactg
601 ctatgccttc tgttgttggg tcctagacct caacgactcc tggcttagca ggagaatgat
661 ccaaagaaca actggatttt tcaaacctta tcaggattgg aacagaaaac ccttaccaac
721 catggatgaa ccgaaaatca agaaggccgc gaatgctgtt ctatgcgcac tctcctcact
781 cttcactaga cccattaagg acatcattgg gaagcttagg ccactgaaca ttcttaatat
841 actggcaacc tgcgattgga cttttgcagg catagtggaa tccatgatcc ttcttgctga
901 actctttggg gtgttctgga cacccccaga tgtgtctgcg atgattgctc ccttactcgg
961 tgactacgag atgcaaggcc ccgaagacct ggctgtggaa cttgtgcccg tggtgatggg
1021 aggaataggt ttggtgttag gattcaccaa agaaaagatc ggcaagatgc tttcatcagc
1081 tgcgaccaca cttagggcct gcaaggattt aggatcttat ggattggaga tactcaaatt
1141 ggtcatgaag tggttctttc ccaagaagga ggaggctaac gaactagcca tggtgagggc
1201 cattgaggat gcagtcctgg atttggaggc aatagaaaac aatcacatga ccacccttct
1261 caaggataaa gacagcctgg ccacatacat gaggactctt gacttggaag aagagaaagc
1321 aaggaaactg tcaaccaaat cggcgtcacc tgacatcgtg ggtacaataa acgcactgct
1381 ggctaggata gcagccgcca ggtcactggt ccacaaggct aaggaggagc tctcgagcag
1441 acagagacct gttgttgtaa tgatatcagg tagaccaggt ataggaaaga cccatctggc
1501 cagagagcta gccaagaaag tcgcgtcaac actgtcaggc gatcaaagga tcggactggt
1561 acctaggaat ggtgtcgacc attgggacgc ctacaaggga gaaagggtgg tcctgtggga
1621 tgattatggt atgagcaacc ctatacagga cgcactgagg ctccaagaat tggctgacac
1681 ctgtcctctg accctaaatt gtgataggat tgaaaacaaa ggaaaagtgt tcgacagtga
1741 tgccataatt ataacaacca accttgcaaa cccagcacca ctagattatg tcaactttga
1801 ggcctgctct agacgcatag acttcttggt gtatgcagac gcacctgata ttgagaaggc
1861 taagcgtgac ttccctggcc aaccagatat gtggaaagac catttcagac cagacttctc
1921 acacattaaa cttcagctgg caccacaggg aggttttgac aaaaatggca acaccccaca
1981 tggcaaaggt gtggtaaagt ccctgacgat tggttctctg atcgccaggg cctccggctt
2041 gctccacgag agaatggatg aatttgagct ccaaggctct gacctgccaa ccttcaattt
2101 tgaccgcaat aaagtcgccg ccttcagaca attagcagct gaaaacaaat atggtcttat
2161 ggacacattg agggtcggca accaactgaa aagtgttaag accctggatg agctgaagca
2221 ggccataaag aacatcagta tcaagaagtg tcagatagtg tataatggat gcacctatac
2281 catggaatct gatgggaggg gcaaggttgt ggttgaaaag gtacaaaacg caacagttca
2341 aaccaacaat gaacttgtag gggcactcca ccacctgaga tctgcaagga taagatacta
2401 tgtcaaatgt ttccaagaag ccatttactc tctactccaa attgctggcg cagcctttgt
2461 cacctcacgc atcgtgaggc gcatgaacat atcaaacctc tggtcgaagc cacccattga
2521 ggagggtgat gagcctgaag acagaggagg atgccccaag cccaggaatg aagatgacct
2581 cactattgac tctagagaca ttaaagtgga agggaagaag ggcaagaata agtctggccg
2641 gggcaagaaa cacacagcct tctcttccaa gggcctcagt gatgaagagt acgatgagta
2701 caagagaatc agagaggaga ggaatggcaa atactcaata gaggaatacc tccaagacag
2761 ggacagatac tatgaagagc ttgccattgc taaggccact gaggaagact tctgtgagga
2821 ggaggagatc aaaatccgcc agagaatctt ccgacccacc aggaagcagc ggaaagagga
2881 aagggccacg cttgggcttg tcacaggatc ggaaatcaga aagaggaatc cagatgactt
2941 taaaccaaaa ggaaaattgt gggctgatga caacaggagc gtggattata atgagaggat
3001 agattttgag gctcccccga gtgtttggtc taggatagtc aactttggca caggctgggg
3061 attctgggtt tctccaagtc tctttataac ttcaacacac gtcataccaa aaggaatcac
3121 tgaggccttt ggagtgtcca taaaccaaat ccaaatccac aaatctggag aattttgccg
3181 cttgcggttt ccaaagccaa ttagaccaga cgtgagtggg atgatcttgg aagagggcgc
3241 ccctgaaggc actgttgtgt ctattctcat caaaaggaca acaggggagc tgatgcctct
3301 tgcagtcaga atggggactc atgccacaat gaaaatccaa ggtagaacgg tgggtggtca
3361 gatgggtatg cttctcactg gctcaaatgc taaaggcatg gatctaggca caacgccagg
3421 tgactgcgga tgtccataca tatacaaaag gggcaatgac cttgtggtca ttggggtgca
3481 cactgcagca gctcgtggag gcaacacggt catatgtgcc acacagggaa gtgagggtga
3541 agccactctt gaaggagatg acaacaaggg tacctattgt ggagccccca ttttgggacc
3601 tggcaatgca ccaaaattga gcacaaagac aaaattctgg agatcctcta acgcaccgct
3661 tcccccaggt acttatgaac caacatacct tggtgggaga gacccgcgcg tgaagggagg
3721 cccatctctg cagcaagtta tgagagatca actcaaacct tttacagagc ccagagggaa
3781 gccaccaaac ccaaatgtct tagagtcagc aaagaagact atcatcaatg ttctggaaca
3841 gaccattgac cctcctcaaa agtggtcata tgcccaagct tgtgcatccc tcgacaagac
3901 aacctccagt ggatacccgc accacgtccg gaagaatgac tactggagtg gtgaatcctt
3961 cacaggaaaa cttgcagatc aggcttcaaa agcaaacctc atgtatgagg aaggcaagca
4021 catgcaacca gtttacaccg cagcactcaa agacgagctc gtgaaaactg acaaaattta
4081 tggcaaaatc aagaaaagac tcctgtgggg ctctgacctc tccacaatga ttcgatgcgc
4141 cagagcattt ggtggtctca tggatgaact caaagcaaat tgtattacac tccctatcag
4201 agttggtatg aatatgaatg aagatggtcc cataatattt gagaaacact ccaggtacag
4261 gtaccactat gatgctgatt actcccgctg ggactccaca caacagcggg cagtgctgga
4321 agcggcactt gaaatcatgg tgagattttc tgctgagcca cagctggcac aaatagtggc
4381 agaggacctg ctgtcaccaa gtgtggttga tgtgggcgat ttcaaaatcg ctatcaatga
4441 aggcctacca tctggcgtgc cttgcacctc acaatggaat tctattgccc actggttact
4501 taccttgtgt gccctttctg aagtgacggg attaggtcct gacatcatac aagctaactc
4561 catgtactct ttctatggtg atgatgagat tgtgagcaca gacataaaat tggacccaga
4621 gaaattgacc gcaaagctca aagaatatgg ccttaaaccc actcggcccg acaaaactga
4681 ggggccgttg gtgattagtg aggacctgaa tgggttgact ttccttcgcc gaacagtcac
4741 ccgtgatcca gcaggttggt ttggaaagtt ggaccaaaac tccatcctca ggcagttgta
4801 ctggacaaga ggacccaacc atgaagaccc cagtgagacc atgataccac acgcacaaag
4861 acctgtgcag ctcatggcac tactaggaga atcctctcta catggaccct cattttacag
4921 caaggttagc aagttagtta tatctgaact taaagaggga ggaatggatt tttatgtgcc
4981 cagacaagag tcaatgttca gatggatgag gttctcagat ctaagcacat gggagggcga
5041 tcgcaatctg gctcccagtt ttgtgaatga agatggcgtc gaatgacgcc gctccatcta
5101 atgatggtgc tgctggtctc gtaccagagg gcaacaacga gacccttccc ctagaaccag
5161 ttgcgggcgc agctatagcc gcacccgtca ctggccaaaa taatataatt gacccctgga
5221 ttagaacaaa ttttgtgcaa gcaccaaatg gagagttcac agtgtcaccc agaaactctc
5281 ctggagaaat tttattaaat ttagagttgg gccctgattt gaacccttat ttggctcatt
5341 tgtcaaggat gtacaatggg tatgctggtg gagtggaagt tcaggttctc ctggcaggga
5401 acgcgttcac tgccggaaag atcctcttcg ccgccgtccc gccaaatttc ccagtggaat
5461 tcttaagccc agcccagatc acaatgctcc cacacttaat agtagatgtt aggactcttg
5521 aaccaattat gatcccactc cctgatgtta ggaatacatt cttccattat agtaaccagc
5581 ctaacagccg catgagatta gtggctatgc tctatacccc actcagatct aatggctcag
5641 gtgatgatgt ctttactgtc tcttgcaggg ttttgactag gcctactcct gattttgagt
5701 tcacttattt agtgccacct tctgttgaat ctaaaactaa gcctttctcc ttacctattt
5761 taaccctttc tgagctcaca aattcgaggt ttccagtccc catcgattcg ctttttaccg
5821 cccagaataa tgtgttgcag gtgcagtgtc aaaatggcag gtgtacactt gatggtgagt
5881 tacaaggcac aacccagttg ctcccaactg gcatctgcgc attcagagga cgggtgacag
5941 cacaaattaa ccaacgtgac aggtggcaca tgcaactgca aaacctcaat ggtacaacat
6001 atgacccaac tgatgatgtg cctgccccgc tgggtacacc tgacttcaag ggcgtcgtgt
6061 ttggaatggt aagccaaaga aatgtgggta atgatgcgcc tggctcaacc agagcccaac
6121 aggcgtgggt ttcaacctat agcccccaat ttgtccccaa attaggttct gtcaatctta
6181 gaatcagtaa taatgatgat ttccaattcc agccaacaaa atttacacca gtgggcatca
6241 atgatgatga tgatgatcac ccgttcagac agtgggagct accaaactat tcaggggagc
6301 ttaccttgaa tatgaatctt gcccccccag ttgctccaaa ttttcctggt gaacaattgt
6361 tattcttcag atctttcgtg ccatgctcag gaggttacaa ccaaggtatt atagattgtc
6421 ttattcccca agaatggatc caacacttct atcaggaatc agcaccctcc cagtcagacg
6481 tggccctaat caggtatgtc aaccccgata cgggacgtac actgtttgaa gcaaaattgc
6541 acagatctgg ttacattact gtggctcact ctggagatta tcctcttgtt gttccggcta
6601 atggacactt tagatttgat tcttgggtaa atcagtttta ctcactcgcc ccaatgggaa
6661 ctgggaatgg gcgaaggagg gctcagtaat ggctggggct ttcattgcag gattggcagg
6721 cgacatgctc acgtcatctg tgggctccct tgtgaacgca ggggcaagcg ccattaacca
6781 aaaggtagac tttgaaaaca acaaacaact ccagtctgct tcctttcagc atgataaaga
6841 gatgctccaa gcgcaggtga gggcaaccaa gcagctgcaa tctgaaatga tagccctaaa
6901 acagggggtt ttggccgcag gcggcttttc ccccactgat gcagcaaggg gatccattgg
6961 tgcacccatg acaaaggtgc ttgactggtc tggtactcga tactgggcgc ccaattccac
7021 aaagacaact ggctactcgg gacaatttac ctcttcacct gtgcatatgt ctagcccaaa
7081 tgctccacaa tcaaaacctg caaagactag gtctctagtt ccttcctcct cttctagtag
7141 tgtttatagt atgtatactc aatctactca tttgacatct ggctcttcta gtaatgcttc
7201 ttctgcctct acaaagttga caaatttaag ctctggcccc tctcaaaaca gaacagcaga
7261 gtgggtgaat caacagagaa gtcttagccc tttcatgagt ggcgcactta acatctcaca
7321 tgttacgcca ccctcaagta gggcttccag ttctgggacg gtctcaaccg tgcccaagga
7381 agttttggac tcctggacgt ctgcgtttaa cacacacaga cagccgctct tcgcacacct
7441 cagggtgagg ggggagtcac gtgtttagtg aaaagaaata attggctata atgtgattt
//