Typing tool
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Typing tool
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Complete norovirus genomes
| PQ336867 | GII.17 | |
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| GII.P17 |
ORF1: 1..5086
ORF2: 5067..6683
ORF3: 6683..7462
LOCUS PQ336867 7493 bp RNA linear VRL 22-OCT-2024
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/WT-NORO-2116/2022/UK
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PQ336867
VERSION PQ336867.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7493)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7493)
AUTHORS Roy,S., Williams,R.J., Tutill,H.J., Wong,S., Celma,C. and Breuer,J.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2024) Division of viral diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7493
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/WT-NORO-2116/2022/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Feb-2022"
/note="genotype: GII.17[P17]"
gene <1..5086
/gene="ORF1"
CDS <1..5086
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XGX96781.1"
/translation="SVAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGARPKQPPPGE
TKQTQRPPRPPTPELVEKIPPPPPNGEDEPKVAYKVGEGVSGLPDLTTVAQPDAQNTA
YSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAKIE
LTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDLNDCWLSRR
MIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIGKLKPLN
IMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAVEL
VPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKEEA
NELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYVRTLDLEEEKARKLSSKSASP
DIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVA
STLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLN
CDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDF
PGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGLLH
ERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQ
AIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHLRSARIR
YYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEDDEPEDKGGCPKPRD
EDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIE
EYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATLGLVTGSEI
RKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFIT
STHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSI
LIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPY
IYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAP
KLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPP
KPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESF
TGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIR
CARAFGGLMDELKANCVTLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQR
AVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVPCTSQWNS
IAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLK
PTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDP
SETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRW
MRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..976
/gene="ORF1"
/product="p48"
mat_peptide 977..2074
/gene="ORF1"
/product="NTPase"
mat_peptide 2075..2611
/gene="ORF1"
/product="p22"
mat_peptide 2612..3010
/gene="ORF1"
/product="VPg"
mat_peptide 3011..3553
/gene="ORF1"
/product="Pro"
mat_peptide 3554..5083
/gene="ORF1"
/product="RdRp"
gene 5067..6683
/gene="ORF2"
CDS 5067..6683
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGX96782.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEFLLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAKTDNSDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DDDHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6683..7462
/gene="ORF3"
CDS 6683..7462
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGX96783.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAISQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGILAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPSAPQSKPAKPRSLGPSSSSSSVYSVSTQST
SLTSGSSSNASSVSTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 ttccgtcgcc gttgctggca aaaacaacaa caacgacaag gaaaaatctt caagtgacag
61 cttgttttct aacatgactg ttacttttaa gaaagccctc ggggcgcggc ctaaacagcc
121 gcccccggga gaaacaaaac aaacacaaag accaccaagg ccaccgacac cggaattggt
181 ggagaagata cccccacccc cccccaatgg cgaggatgaa ccaaaggtag cgtataaggt
241 gggagaaggt gtgtctgggc tgcccgactt aacaaccgtg gcacaacctg acgcacagaa
301 cacagcctat agtgtccccc cacttagcca gagagaggtc ggcgaagcta aagaaccgtt
361 gcctggctcc attctggaaa tgtgggatgg tgagatctac cactatgggc tgtatgttga
421 gcgggggcat gtactgggag tgcacaaacc acctgccgca ataagtcttg ccaaaattga
481 attaacaccg ctgtctctct actggagagt ggtttacact ccccagtatt tgatagctcc
541 agagaccctt aagaatttaa atggagaggc tttcccatac acggcctttg acaacaactg
601 ttatgccttc tgttgttggg ttctagacct caacgactgc tggctcagca gaaggatgat
661 ccaaagaaca actggattct tcagaccgta tcaggactgg aacagaaaac ccttgccaac
721 catggatgaa ccaaaaatca aaaaggccgc gaatgctgtt ctgtgtgctc tctcctcact
781 cttcactagg cccatcaaag atgtcattgg aaagctcaaa ccactgaaca ttatgaacat
841 actggcaact tgtgattgga cttttgcggg catagtggaa tccatgatcc ttcttgctga
901 gctctttggg gtgttctgga cgcccccaga tgtgtctgca atgattgctc ccttactcgg
961 tgactacgag atgcaaggcc ccgaagacct ggccgtggaa cttgtgcccg tggtaatggg
1021 aggaataggt ttggtgttag gattcaccaa ggaaaagatc ggcaagatgc tttcatcagc
1081 tgcaaccaca ctcagggcct gtaaggatct aggatcttat gggttagaga tactcaaact
1141 ggttatgaag tggttcttcc ctaaaaagga ggaggccaac gagttggcca tggtgagggc
1201 cattgaggat gcagttctgg atttggaggc aatagaaaac aaccacatga ccactctcct
1261 taaggacaaa gacagcctgg ccacatacgt gagaactctt gacttggaag aagaaaaagc
1321 aaggaagctg tcatccaaat cggcgtcacc tgatatcgtg ggcacagtaa acgcattatt
1381 ggcaaggata gcagccgcca ggtcactggt tcacaaggct aaggaggagc tctcgagcag
1441 acagaggcct gttgttgtaa tgatatcagg taggccaggt ataggaaaga cccatctggc
1501 cagagagcta gccaagaagg ttgcgtcaac actgtcaggc gaccaaagga ttggactgat
1561 acctagaaat ggcgtcgacc attgggacgc ctacaaagga gagcgggtgg ttctgtggga
1621 tgactatggc atgagcaacc ccatacagga cgcactgaga ctccaagaat tggctgatac
1681 ctgccccctg accctaaatt gtgacaggat tgaaaacaaa ggaaaagtgt ttgacagtga
1741 cgccataatc ataacaacca accttgcaaa cccagcacca ctggattatg tcaactttga
1801 ggcttgttct agacgcatag acttcttggt gtatgcagac gcacctgaca tcgagaaggc
1861 taagcgtgac ttccctggcc aaccagatat gtggaaagac cattacagat cagacttctc
1921 acacattaaa ctccagctgg caccacaggg gggctttgat aagaatggca ataccccaca
1981 tggcaaaggt gtggttaagt ctctgacgat tggttctctg atcgccaggg cttctggctt
2041 gctccatgag agaatggatg aattcgagct ccaaggctct gacttaccaa ccttcaattt
2101 cgaccgtaac aaagtcgccg ccttcagaca attggcagct gaaaacaaat atggtcttat
2161 ggacacactg agggtcggca accaactgaa aagtgtcaaa accctggatg agctgaagca
2221 ggctataaag aacatcacca tcaagaagtg ccagatagtg tacaatggat gcacctacac
2281 catggaatct gatgggagga acaaggttgt ggttgaaaag gttcaaaatg caacagtcca
2341 aaccaacaat gaacttgcag gagcactcca ccacctgaga tctgcaagga taaggtatta
2401 tgtcaaatgt ttccaagaag ctatttactc tctactccaa attgctggtg cagccttcgt
2461 caccacacgc atcgtgaggc gcatgaacat ctcaaacctc tggtcgaaac cacccgttga
2521 agaggatgat gagcctgaag acaaaggggg gtgccccaag cccagggatg aagatgacct
2581 cactattgac tctaaagaca ttaaagcaga agggaagaag ggcaagaaca aatctggccg
2641 gggcaagaaa cacacagctt tctcatccaa gggcctcagt gatgaagagt acgatgagta
2701 caagagaatc agggaggaga ggaatggcaa atactcaata gaagaatacc tccaggatag
2761 ggatagatac tatgaagagc ttgccattgc taaggccact gaggaagact tctgtgaaga
2821 ggaggaaatc aaaattcgcc agagaatctt ccggcccacc aggaagcaac ggagagagga
2881 aagagccacg cttgggcttg tcacaggatc ggaaatcaga aagaggaacc cagatgactt
2941 taagccaaaa gggaaattgt gggctgatga caacagaagt gtggactaca atgagaggat
3001 agattttgag gctcccccaa gtgtttggtc taggatagtc aactttggta caggatgggg
3061 attctgggtc tccccaagtc tctttataac ttcaacacat gtcataccaa aaggaatcac
3121 tgaggctttt ggagtcccca ttaaccaaat tcaaatacac aaatctggag agttttgccg
3181 cttgcggttt ccaaaaccaa tcaggccaga cgtgagtgga atgatcttgg aagagggagc
3241 ccctgaaggc actgttgtat ccattctcat caagaggaca acaggggaac tgatgcctct
3301 cgcagttaga atgggaactc atgccacaat gaaaatccaa ggtagaacgg tgggtggtca
3361 aatgggcatg cttctcactg gctcaaacgc taaaagcatg gacctaggca caacaccagg
3421 tgactgtggg tgcccataca tatataaaag gggcaatgac ttcgtggtca ttggggtgca
3481 cactgcagca gcccgtggag gcaacacggt catatgtgcc acacagggaa gcgaaggcga
3541 agccaccctc gaaggaggtg acaacaaggg cacctattgt ggagccccca tcttgggacc
3601 tggcaacgca ccaaaattga gcacgaaaac aaaattctgg agatcttcta acgcgccgct
3661 tcctccaggc acctatgaac cagcatacct tggtggaaaa gacccgcgtg tgaagggagg
3721 cccctctcta caacaggtta tgagagacca acttaaacct tttacagagc ccagagggaa
3781 accaccaaaa ccaagtgtcc tagaatcagc aaagaagacc atcattaatg ttctggaaca
3841 aaccattgac ccccctgaaa agtggtcata tgcccaagct tgtgcatccc tcgacaagac
3901 aacctccagt ggatacccgc atcacgtccg gaagaatgac tattggagtg gtgaatcctt
3961 cacggggaaa cttgcagacc aggcctcaaa agcaaacctt atgtatgagg aaggcaagca
4021 catgcaacca gtttacactg cagcactcaa agacgagctc gtgaaaactg acaaaattta
4081 tggcaagatc aagaaaagac tcctgtgggg ctctgaccta tccaccatga ttcgatgcgc
4141 cagggcattt ggtggcctca tggatgagct caaagcaaat tgtgtcacac ttcctatcag
4201 agttggtatg aacatgaatg aagatggtcc cataatattt gaaaagcact ccaggtacag
4261 gtaccactat gatgctgatt actcccgctg ggattccaca caacagcggg cagtgctgga
4321 agcggcactt gaaatcatgg tgagattctc tgctgagcca cagttggcac aaatagtggc
4381 agaggacctg ctatcaccaa gtgtggttga tgtgggcgat ttcaaaatta ctatcaatga
4441 aggcctacca tctggcgtgc cttgcacttc acaatggaat tctattgccc actggttact
4501 caccctgtgt gccttgtctg aagtaacggg actaggccct gacatcatac aagccaactc
4561 catgtactct ttctatggtg atgatgagat tgtgagcaca gacataaaat tagacccaga
4621 gaaattgact gcaaaactca aagaatacgg tcttaaaccc acccggcctg acaagactga
4681 ggggccactg gtaattagtg aggacctgaa tgggttgact ttcctccgcc gaacagtcac
4741 ccgcgatcca gcgggttggt ttggaaagtt agaccaaaac tccatcctca ggcagctgta
4801 ctggacaagg gggcccaatc atgaagaccc cagtgagact atgataccac acgcacagag
4861 acctgtgcag ctcatggcac tgctaggaga gtcctcccta catggaccct cattttacag
4921 caaggttagc aagctggtca tatctgaact taaagaggga ggaatggatt tttatgtgcc
4981 cagacaagag tcaatgttca ggtggatgag gttctcagat ctaagcacat gggagggcga
5041 tcgcaatctg gctcccagtt ttgtgaatga agatggcgtc gaatgacgcc gctccatcta
5101 atgatggtgc tgctggtctc gtaccagagg gcaataacga gacccttccc ctagaaccag
5161 ttgcgggcgc agctatagcc gcacccgtca ctggccaaaa caatataatt gacccctgga
5221 ttagaacaaa ttttgtgcaa gcaccaaatg gagagttcac agtgtcaccc agaaactctc
5281 ctggagaatt tttactaaac ctagagttgg gccctgattt gaacccttat ttggctcatt
5341 tgtcaaggat gtacaatggg tatgctggtg gagttgaagt ccaggttctc ctggcaggga
5401 acgcgttcac tgccgggaag atccttttcg ccgctgtccc gccaaatttc ccagtggaat
5461 tcttaagccc agcccagatt acaatgctcc cacatataat agtagatgtt aggactcttg
5521 aaccaattat gatcccatta cctgatgtta ggaacacatt cttccactat aataaccagc
5581 ccaacagccg catgagatta gtggctatgc tctatactcc ccttagatcc aatggctcag
5641 gtgatgatgt tttcactgtt tcttgcaggg ttttaactag gcctactcct gattttgagt
5701 tcacttacct agtgccaccc tctgttgaat ctaagactaa gcccttttcc ttacctattc
5761 taaccctttc tgagctcaca aattcgaggt tcccggtccc cattgattcg cttttcaccg
5821 cccagaataa tgtgttgcag gtgcagtgtc aaaatggcag gtgcacactt gacggtgagc
5881 tacaaggcac aacccagttg ctcccatctg gcatctgtgc gttcagagga cgggtgacag
5941 caaaaactga caattctgac aagtggcaca tgcaactgca aaacctcaat ggcacaacat
6001 atgacccaac tgatgatgtg ccagccccac tgggtacacc tgacttcaag ggcgtcgtgt
6061 ttgggatggc aagccaaaga aatgtgggta acgatgcgcc cggctcaacc agggctcatg
6121 aggcggtgat ttcaacctac agccccagat ttgttcccaa attaggctct gtcaatttta
6181 aaagtaatga cgatgatttc caattgcagc caacaagatt cacaccagtg ggcattaatg
6241 atgatgacga ccacccgttc agacaatggg aactaccaga ctattcaggg gtgcttacct
6301 tgaatatgaa ccttgcccct ccggttgctc caaatttccc tggtgaacaa ttattattct
6361 tcagatcttc cgtgccatgc tcaggaggtt acaaccaagg tattatagat tgtcttatcc
6421 cccaagaatg gatccaacac ttctaccagg agtcagcacc ttctcagtca gacgtggccc
6481 tgataaggta cgtcaacccc gacacgggtc gcacactgtt tgaggcaaaa ttgcacagat
6541 ctggctatat tactgtggct cactctggag actatcctct tgttgttccg gctaatggat
6601 actttagatt tgactcttgg gtaaatcagt tttactcact cgccccaatg ggaactggga
6661 atgggcgaag gagggctcag taatggctgg agctttcatt gcaggattgg caggcgacat
6721 gctcacgtca tctgtgggct ccctggtgaa cgcaggggca aacgccatca gccaaaagat
6781 agactttgaa aacaacaaac agctccagtc tgcttccttt caacatgata aagagatgct
6841 ccaagcgcag gtgaatgcaa ccaagcagct gcaatctgag atgatagccc taaaacaggg
6901 gattttggcc gcaggcggct tttcccccac tgatgcagcg aggggggcca tcggtgcacc
6961 catgacaaag gtgcttgact ggtctggcac tcgatactgg gctcccaatt ccacaaagac
7021 aactggttat tcggggcaat tcacctcttc acctgtgcac atgtccagcc cgagtgctcc
7081 acaatcaaaa cccgcaaagc ccaggtctct aggtccttct tcttcttcta gtagtgttta
7141 tagtgtgtct acccaatcaa cttctctaac atctggctct tctagtaatg cttcttccgt
7201 ttctacaaaa ttgacaaatt taagctccgg ctcctctcaa aacagaacag cagagtgggt
7261 gaaccaacag agaagtctca gccctttcat gagtggcgca ctcaatatct cacatgtcac
7321 gccaccttca agtagggcct ccagttctgg gacggtctca accgtgccca aggaagtttt
7381 ggactcctgg acatctgcat tcaacacacg cagacagccg ctcttcgcac acctcagagt
7441 gaggggggag tcacgtgttt agtgaaaaga aataattggc tataatatga ttt
//