Typing tool
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Typing tool
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Complete norovirus genomes
| PQ336865 | GII.17 | |
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| GII.P17 |
ORF1: 1..5086
ORF2: 5067..6683
ORF3: 6683..7462
LOCUS PQ336865 7493 bp RNA linear VRL 22-OCT-2024
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/WT-NORO-2196/2022/UK
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PQ336865
VERSION PQ336865.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7493)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7493)
AUTHORS Roy,S., Williams,R.J., Tutill,H.J., Wong,S., Celma,C. and Breuer,J.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2024) Division of viral diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7493
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/WT-NORO-2196/2022/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Apr-2022"
/note="genotype: GII.17[P17]"
gene <1..5086
/gene="ORF1"
CDS <1..5086
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XGX96775.1"
/translation="SVAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGARSKQPPPGE
TKQTQRPPRPPTPELVKKIPPPPPNGEDEPKIAYKVGEGVSGLPDLTTVAQPDAQNTA
YSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGLVLGVHKPPAAISLAKIE
LTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLSRR
MIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIGKLKPLN
IMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAIEL
VPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKEEA
NELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRSLDLEEEKARKLSSKSASP
DIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVA
STLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLN
CDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDF
PGQPDMWKDHYRSDFSHIKLHLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGLLH
ERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLVDTLRVGNQLKSVKTLDELKQ
AIKSITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHLRSARIR
YYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGGCPKPRD
EDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIE
EYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATLGLVTGSEI
RKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFIT
STHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSI
LIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPY
IYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAP
KLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPP
KPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESF
TGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIR
CARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQR
AVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVPCTSQWNS
IAHWLLTLCALSEVTGLDPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLREYGLK
PTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDP
SETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKGGGMDFYVPRQESMFRW
MRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..976
/gene="ORF1"
/product="p48"
mat_peptide 977..2074
/gene="ORF1"
/product="NTPase"
mat_peptide 2075..2611
/gene="ORF1"
/product="p22"
mat_peptide 2612..3010
/gene="ORF1"
/product="VPg"
mat_peptide 3011..3553
/gene="ORF1"
/product="Pro"
mat_peptide 3554..5083
/gene="ORF1"
/product="RdRp"
gene 5067..6683
/gene="ORF2"
CDS 5067..6683
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGX96776.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPKFVPKLGSVNFRSNDNDFQLQPTRFTPVGIND
DGDHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLLFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6683..7462
/gene="ORF3"
CDS 6683..7462
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGX96777.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAISQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTRVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKPRSLGSSSSSSSVYSMSTQST
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTPAFNTRRQPLFAHLRMRGESRV"
ORIGIN
1 ttccgtcgcc gttgctggca aaaacaacaa caacgacaag gaaaaatctt caagtgatag
61 cttgttttct aacatgactg ttacttttaa gaaagccctc ggggcgcggt ctaaacagcc
121 gcccccggga gaaacaaaac aaacacaaag accaccaagg ccaccgacac cggaattggt
181 gaagaagata cccccacccc cccccaatgg cgaggatgaa ccaaagatag catataaggt
241 gggagaaggt gtgtctgggc tgcccgactt aacaaccgtg gcacaacctg acgcacagaa
301 cacagcctat agtgtccccc cacttagcca gagagaggtc ggtgaagcta aagaaccgtt
361 gcctggctcc attctggaaa tgtgggatgg tgagatctac cactatgggc tgtatgttga
421 gcgggggctt gtactgggag tgcacaaacc acctgccgca ataagccttg ccaaaattga
481 attaacaccg ctgtctctct actggagagt ggtttacact ccccagtatt tgatagctcc
541 agagaccctt aagaatttaa acggagaggc tttcccatac acggcctttg acaacaactg
601 ttatgccttc tgttgttggg ttctagacct caacgactcc tggcttagca gaagaatgat
661 ccaaagaaca actggattct tcagaccgta tcaggactgg aacagaaaac ccttgccaac
721 catggatgaa ccaaaaatca agaaggccgc gaatgctgtt ctgtgtgctc tctcctcact
781 cttcactagg cccatcaaag atgtcattgg aaagcttaaa ccactgaaca ttatgaacat
841 actggcaact tgtgattgga cttttgcggg tatagtggaa tccatgatcc ttcttgctga
901 gctctttggg gtgttctgga cgcccccaga tgtgtctgca atgattgctc ccttactcgg
961 tgactacgag atgcaaggcc ccgaagacct ggccatagaa cttgtgcccg tggtaatggg
1021 aggaataggt ctggtgttag gattcaccaa ggaaaagatc ggcaagatgc tttcatcagc
1081 cgcgaccaca ctcagggcct gtaaggatct aggatcttat gggttggaga tactcaaact
1141 ggtcatgaag tggttcttcc ccaagaagga ggaggccaac gagttagcca tggtgagggc
1201 cattgaggat gcagttctgg atttagaggc aatagaaaac aaccacatga ccactctcct
1261 taaggacaaa gacagcctgg ccacatacat gaggtctctt gacttggaag aagaaaaagc
1321 aaggaaactg tcatccaaat cggcgtcacc tgacatcgtg ggcacagtaa acgcattatt
1381 ggcaaggata gcagccgcca ggtcactggt ccacaaggct aaggaggagc tctcgagcag
1441 acagaggcct gttgttgtaa tgatatcagg taggccaggt ataggaaaga cccatctggc
1501 cagagagcta gccaagaagg ttgcgtcaac actgtcaggt gaccaaagga ttggactgat
1561 acctagaaat ggcgtcgacc attgggacgc ctacaaagga gagcgggtag ttctgtggga
1621 tgactatggc atgagcaacc ctatacagga cgcactgagg ctccaagaat tggctgacac
1681 ctgtcctctg accctaaact gtgacaggat tgaaaacaaa ggaaaagtgt tcgacagtga
1741 cgccataatc ataacaacca accttgcaaa cccagcacca ctagattatg tcaactttga
1801 ggcttgttcc aggcgcatag acttcttggt gtatgcagac gcacctgaca tcgagaaggc
1861 taagcgtgac ttccctggcc aaccagatat gtggaaagac cattacaggt cagacttctc
1921 acacattaaa cttcatctgg caccacaggg aggctttgat aagaatggca acaccccaca
1981 tggtaaaggt gtggttaagt ctctgacgat tggttctctg atcgccaggg cttctggttt
2041 gctccatgag agaatggatg aattcgagct ccaaggctct gatttaccaa ccttcaattt
2101 cgaccgtaac aaagtcgccg ccttcagaca attggcagct gaaaacaaat atggtcttgt
2161 ggacacactg agggtcggca accaactgaa aagtgtcaaa accctggatg agctgaagca
2221 ggctataaag agcatcacca tcaagaagtg ccagatagtg tacaatggat gcacctacac
2281 catggaatct gatggaagga acaaggttgt ggttgaaaag gtccaaaacg caacagttca
2341 aaccaacaat gaacttgcag gagcactcca ccacctgaga tctgcaagga taaggtatta
2401 tgtcaaatgt ttccaagaag ctatttactc cctactccaa attgctggtg cagccttcgt
2461 caccacacgc atcgtgaggc gcatgaacat ctcaaacctc tggtcgaagc cacccgtcga
2521 agagggtgat gagcctgaag acaaaggggg gtgccccaag cccagggatg aagatgacct
2581 cactattgac tctaaagaca ttaaagcaga agggaagaag ggcaagaaca aatctggccg
2641 gggcaagaaa cacacagctt tctcatccaa gggcctcagt gatgaagagt acgatgagta
2701 caagagaatc agggaggaga gaaatggcaa atactcaata gaagaatacc tccaggatag
2761 ggatagatac tatgaagagc ttgccattgc taaggccact gaggaagact tctgtgaaga
2821 ggaggaaatc aaaattcgcc agagaatctt ccggcccacc aggaagcaac ggagagagga
2881 aagagccacg cttgggcttg tcacaggatc ggaaatcaga aagaggaacc cagatgactt
2941 caagccaaaa ggaaaattgt gggctgatga caacagaagt gtggactaca atgagaggat
3001 agattttgag gctcccccga gtgtttggtc taggatagtc aactttggta caggatgggg
3061 attctgggtc tccccaagtc tctttataac ttcaacacat gtcataccaa aaggaatcac
3121 tgaggccttt ggagttccca ttaaccaaat tcaaattcac aaatctggag agttttgccg
3181 cttgcggttt ccaaaaccaa tcaggccaga cgtgagtgga atgatcttgg aagagggtgc
3241 ccctgaaggc actgttgtgt ccattctcat caagagaaca acaggggaac tgatgcctct
3301 cgcagttaga atgggaactc atgccacaat gaaaatccaa ggtagaacgg tgggtggtca
3361 aatgggcatg cttctcactg gctcaaatgc taaaagcatg gacctaggca caacaccagg
3421 tgactgtggg tgcccataca tatacaaaag aggcaatgac ttcgtggtca ttggggtgca
3481 cactgcagca gcccgtggag gcaacacggt catatgtgcc acacagggaa gtgaaggcga
3541 agccaccctc gaaggaggtg acaataaggg cacctattgt ggagccccca tcttgggacc
3601 tggcaacgca ccaaaattga gcacaaaaac aaaattctgg agatcttcta acgcgccgct
3661 tcctccaggc acctatgaac cagcatacct tggtggaaaa gacccgcgtg tgaagggagg
3721 cccatctcta caacaggtta tgagagacca acttaaacct tttacagagc ccagagggaa
3781 gccaccaaaa ccaagtgtcc tagaatcagc aaagaagacc atcattaatg ttctggaaca
3841 aaccattgac ccccctgaaa agtggtcata tgcccaagct tgtgcatctc tcgacaagac
3901 aacctccagt ggatacccgc atcacgtccg gaagaatgac tattggagtg gtgaatcctt
3961 cacggggaag cttgcagacc aggcctcaaa agcaaacctt atgtatgagg aaggcaagca
4021 catgcaacca gtttacaccg cagcactcaa agacgagctc gtgaaaactg acaaaattta
4081 tggcaagatc aagaaaagac tcctatgggg ctctgatcta tccaccatga ttcgatgcgc
4141 cagggcattt ggtggcctca tggatgagct caaagcaaat tgcatcacac tccctatcag
4201 agttggtatg aacatgaatg aagatggtcc cataatattt gaaaagcact ccaggtacag
4261 gtaccactat gatgctgatt actcccgctg ggattccaca caacagcggg cagtgctgga
4321 agcggcactt gaaatcatgg tgagattttc tgctgagcca cagttggcac aaatagtggc
4381 agaggacctg ctatcaccaa gtgtggttga tgtgggcgat ttcaaaatta ctatcaatga
4441 aggcctacca tctggcgtgc cttgcacttc acaatggaat tctattgccc actggttact
4501 caccctgtgt gccctgtctg aagtaacagg actagaccct gacatcatac aagccaactc
4561 catgtactct ttctatggtg atgatgagat tgtgagcaca gacataaaat tggacccaga
4621 aaaattgact gcaaaactca gagaatatgg tctcaaaccc acccggcctg acaagactga
4681 ggggccactg gtaatcagtg aggatctgaa tgggttgact ttcctccgcc gaacagtcac
4741 ccgcgatcca gcgggttggt ttggaaagtt ggaccaaaac tccatcctca ggcagctgta
4801 ctggacaagg ggacccaacc atgaagaccc cagtgagact atgataccac acgcacagag
4861 acctgtgcag ctcatggcac tgctaggaga gtcctcccta catggaccct cattttacag
4921 caaagttagc aagctggtca tatctgaact taaagggggg ggaatggatt tttatgtgcc
4981 cagacaagag tcaatgttca gatggatgag gttctcagat ctaagcacat gggagggcga
5041 tcgcaatctg gctcccagtt ttgtgaatga agatggcgtc gaatgacgcc gctccatcta
5101 atgatggtgc tgctggtctc gtaccagagg gcaataacga gacccttccc ctagaaccag
5161 ttgcgggcgc agctatagcc gcacccgtca ctggccaaaa caatataatt gacccctgga
5221 ttagaacaaa ttttgtacaa gcaccaaatg gagagttcac agtgtcaccc agaaactctc
5281 ctggagaaat tttgctaaac ctagagttgg gccctgattt gaacccttat ttggctcatt
5341 tgtcaaggat gtacaatggg tatgctggtg gagttgaagt tcaggttctc ctggcaggga
5401 acgcgttcac tgccgggaag atcctcttcg ccgctgtccc gccaaatttc ccagtggaat
5461 tcttaagccc agcccagatt acaatgctcc cacatataat agtagatgtt aggactcttg
5521 aaccaattat gatcccatta cctgatgtta ggaacacatt cttccactat aataaccagc
5581 ccaacagccg catgagatta gtggctatgc tctatacccc ccttagatct aatggctcag
5641 gtgatgatgt tttcactgtt tcttgcaggg tcttgactag gcctacccct gattttgagt
5701 tcacttacct agtgccaccc tctgttgaat ctaagactaa gcccttttcc ttacccattc
5761 taaccctttc tgagctcaca aattcgaggt tcccggtccc cattgattcg cttttcaccg
5821 cccagaataa tgtgttgcag gtgcagtgtc aaaatggcag gtgcacactt gacggtgagc
5881 tacaaggcac aacccagttg ctcccatctg gcatctgtgc gttcagagga cgggtgacag
5941 cagaaactga caatcctgac aagtggcaca tgcaactgca aaacctcaat ggcacaacat
6001 atgacccaac tgatgatgtg ccagccccac tgggtacacc tgacttcaag ggcgtcgtgt
6061 ttgggatggc aagccaaaga aatgtgggta acgatgcgcc cggctcaacc agggcccatg
6121 aggcggtgat ttcaacctac agccccaaat ttgttcccaa attaggctct gtcaatttta
6181 gaagtaatga caatgatttc caattgcagc caacaagatt cacaccagtg ggcattaatg
6241 atgatggcga ccacccgttc agacaatggg aactgccaga ctattcaggg gtgcttacct
6301 tgaatatgaa ccttgccccc ccggttgctc caaatttccc tggtgaacaa ttattactct
6361 tcagatcttc cgtgccatgt tcaggaggtt acaaccaagg tattatagat tgtcttatcc
6421 cccaagaatg gatccaacac ttctaccagg aatcagcacc ttctcagtca gacgtggccc
6481 tgatcaggta cgtcaacccc gacacgggtc gcacactgtt tgaggcaaaa ctgcacagat
6541 ctggctatat cactgtggct cactctggag actatcctct tgttgttccg gctaatggat
6601 actttagatt tgactcttgg gtaaatcagt tttactcact cgccccaatg ggaactggga
6661 atgggcgaag gagggctcag taatggctgg agccttcatt gcaggattgg cgggtgacat
6721 gctcacgtca tccgtgggct ccctggtgaa cgcaggggca aacgccatca gccaaaagat
6781 agactttgaa aacaacaaac aactccagtc tgcttccttt caacatgata aagagatgct
6841 ccaagcgcag gtgaatgcaa ccaagcagct gcaatctgag atgatagccc taaaacaggg
6901 ggttttggcc gcaggcggct tttcccccac tgatgcagcg aggggggcca tcggtgcacc
6961 catgacaagg gtgcttgact ggtctggcac tcgatactgg gctcccaatt ccacaaagac
7021 aactggttat tcggggcaat tcacctcttc acctgtgcat atgcccagcc cgagtgctcc
7081 acaatcaaaa cccgcaaagc ccaggtctct aggttcttct tcttcttcta gtagtgttta
7141 tagtatgtct acccaatcaa cttctctaac atctggctct tctagtaatg cttcttctgc
7201 ttctacaaaa ctgacaaatt taagctccgg ctcctctcaa aacagaacag cagagtgggt
7261 gaaccaacag agaagtctca gccccttcat gagtggcgca ctcaatatct cacatgtcac
7321 gccaccttca agtagggcct ccagttctgg gacggtctca accgtgccca aggaagtttt
7381 ggactcctgg acacctgcat tcaacacacg cagacagccg ctcttcgcac acctcagaat
7441 gaggggggag tcacgtgttt agtgaaaaga aataattggc tataatatga ttt
//