Typing tool
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Typing tool
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Complete norovirus genomes
| PQ336864 | GII.17 | |
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| GII.P17 |
ORF1: 1..5086
ORF2: 5067..6683
ORF3: 6683..7462
LOCUS PQ336864 7493 bp RNA linear VRL 22-OCT-2024
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/WT-NORO-2306/2021/UK
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PQ336864
VERSION PQ336864.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7493)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7493)
AUTHORS Roy,S., Williams,R.J., Tutill,H.J., Wong,S., Celma,C. and Breuer,J.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2024) Division of viral diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7493
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/WT-NORO-2306/2021/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Nov-2021"
/note="genotype: GII.17[P17]"
gene <1..5086
/gene="ORF1"
CDS <1..5086
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XGX96772.1"
/translation="SVAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGARSKQPPPGE
TKQTQRPPRPPTPELVKKIPPPPPNGEDEPKIAYKVGEGVSGLPDLTTVAQPDAQNTA
YSVPPLSQREAGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAKIE
LTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLSRR
MIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIGKLKPLN
IMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAVEL
VPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKEEA
NELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSSKSASP
DIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVA
STLSGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLN
CDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDF
PGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGLLH
ERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQ
AIKNITIKKCQIVYNGCTYTVESDGRNKVVVEKVQNATVQTNNELTGALHHLRSARIR
YYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGNEPEDKGGCPKPRD
EDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIE
EYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATLGLVTGSEI
RKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFIT
STHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSI
LIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPY
IYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAP
KLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPP
KPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESF
TGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIR
CARAFGGLMDELKANCITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQR
AVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIVINEGLPSGVPCTSQWNS
IAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLK
PTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDP
SETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRW
MRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..976
/gene="ORF1"
/product="p48"
mat_peptide 977..2074
/gene="ORF1"
/product="NTPase"
mat_peptide 2075..2611
/gene="ORF1"
/product="p22"
mat_peptide 2612..3010
/gene="ORF1"
/product="VPg"
mat_peptide 3011..3553
/gene="ORF1"
/product="Pro"
mat_peptide 3554..5083
/gene="ORF1"
/product="RdRp"
gene 5067..6683
/gene="ORF2"
CDS 5067..6683
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGX96773.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLLFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6683..7462
/gene="ORF3"
CDS 6683..7462
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGX96774.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAISQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKSRSLGSSSSSSSVYSMSTQST
SLTSGSSSNASSASTKLTNLGSGSSRNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 ttccgtcgcc gttgctggca aaaacaacaa caacgacaag gaaaaatctt caagtgacag
61 cttgttttct aacatgactg ttacttttaa gaaagccctc ggggcgcggt ctaaacagcc
121 gcccccggga gaaacaaaac aaacacaaag accaccaagg ccaccgacac cggaattggt
181 gaagaagata cccccacccc cccccaatgg tgaggatgaa ccaaagatag cgtataaggt
241 gggagaaggt gtgtctgggc tgcccgactt gacaaccgtg gcacaacctg acgcacagaa
301 cacagcctac agtgtccccc cacttagcca gagagaggcc ggcgaagcta aagaaccgtt
361 gcctggctcc attctggaaa tgtgggatgg tgagatctac cactatgggc tgtatgttga
421 gcgggggcat gtactgggag tgcacaagcc acctgccgca ataagccttg ccaaaattga
481 attaacaccg ctgtctctct actggagagt ggtttacact ccccaatatt tgatagctcc
541 agagaccctt aagaatttaa atggagaggc tttcccatac acggcctttg acaacaactg
601 ttatgccttc tgttgttggg ttttagacct caacgactcc tggcttagca gaagaatgat
661 ccaaagaaca actggattct tcagaccgta tcaggactgg aacagaaaac ccttgccaac
721 catggatgaa ccaaaaatca agaaggccgc gaatgctgtt ctgtgtgctc tctcctcact
781 cttcactagg cccatcaaag acgtcattgg aaagctcaaa ccactgaaca ttatgaacat
841 actggcaact tgtgattgga cttttgcggg catagtggaa tccatgatcc ttcttgctga
901 gctctttggg gtgttctgga cgcccccaga tgtgtctgca atgattgctc ccttactcgg
961 tgactacgag atgcaaggcc ccgaagacct ggccgtggaa cttgtgcccg tggtaatggg
1021 aggaataggt ttggtgttag gattcaccaa ggaaaagatc ggcaagatgc tttcatcagc
1081 tgcgaccaca ctcagggcct gtaaggatct aggatcttat gggttggaga tactcaaact
1141 ggtcatgaag tggttcttcc ccaagaagga ggaggccaac gagttagcca tggtgagggc
1201 cattgaggat gcagttctgg atttggaggc aatagaaaac aaccacatga ccactctcct
1261 taaggacaaa gacagcctgg ccacatacat gaggactctt gacttggaag aagaaaaagc
1321 aaggaaactg tcatccaaat cggcgtcacc tgacatcgtg ggcacagtaa acgcattatt
1381 ggcaaggata gcagccgcca gatcactggt ccacaaggct aaggaggagc tctcgagcag
1441 acagaggcct gttgttgtaa tgatatcagg taggccaggt ataggaaaga cccatctggc
1501 cagagagcta gccaagaagg ttgcgtcaac actgtcaggt gaccaaaggg ttggactgat
1561 acccagaaat ggcgtcgacc attgggacgc ctacaaagga gagcgggtgg ttctgtggga
1621 tgactatggc atgagcaacc ctatacagga cgcactgagg ctccaagaat tggctgacac
1681 ctgtcctctg accctaaatt gtgacaggat tgaaaacaaa ggaaaagtgt tcgacagtga
1741 cgccataatt ataacaacca acctcgcaaa cccagcacca ctggattatg tcaactttga
1801 ggcttgttct agacgcatag acttcttggt gtatgcagac gcacctgaca tcgagaaggc
1861 taagcgtgac ttccctggcc aaccagatat gtggaaagac cattacagat cagacttctc
1921 acacattaaa cttcagctgg caccacaggg aggctttgat aagaatggca acaccccaca
1981 tggcaaaggt gtggttaagt ctctgacgat tggttctctg atcgccaggg cttctggctt
2041 gctccatgag agaatggatg aatttgagct ccaaggctct gatttaccaa ccttcaattt
2101 cgaccgtaac aaagtcgccg ccttcagaca attggcagct gaaaacaaat atggtcttat
2161 ggacacactg agggtcggca accaactgaa aagtgtcaaa accctggatg agctgaagca
2221 ggctataaag aacatcacca tcaagaagtg ccagatagtg tacaatggat gcacctacac
2281 cgtggaatct gatgggagga acaaggttgt ggttgagaag gttcaaaatg caacagtcca
2341 aaccaacaat gaacttacag gagcactcca ccacctgaga tctgcaagga taaggtatta
2401 tgttaaatgt ttccaagaag ctatttactc tctactccaa attgctggtg cagccttcgt
2461 caccacacgc atcgtgaggc gcatgaacat ctcaaacctc tggtcgaagc cacccgtcga
2521 agagggtaat gagcctgaag acaaaggggg gtgccccaag cccagggatg aagatgacct
2581 cactattgac tctaaagaca ttaaagcaga agggaagaag ggcaagaaca aatctggccg
2641 gggcaagaaa cacacagctt tctcatccaa gggcctcagt gatgaagagt acgatgagta
2701 caagagaatc agggaggaga ggaatggcaa atactcaatt gaagaatacc tccaggacag
2761 ggatagatac tatgaagagc ttgccattgc taaggccact gaggaagact tctgtgaaga
2821 ggaggaaatc aaaattcgcc agagaatctt ccggcccacc aggaagcaac ggagagagga
2881 aagagccacg cttgggcttg tcacaggatc ggaaatcaga aagaggaacc cagatgactt
2941 taagccaaaa ggaaaacttt gggctgatga caacagaagt gtggactaca atgagaggat
3001 agattttgag gctcccccga gtgtttggtc taggatagtc aactttggta caggatgggg
3061 attctgggtc tccccaagtc tctttataac ttcaacacat gtcataccaa aaggaatcac
3121 tgaggccttt ggagttccca ttaaccaaat tcaaattcac aaatctggag agttttgccg
3181 cttgcggttt ccaaaaccaa tcaggccaga cgtgagtgga atgatcttgg aagagggtgc
3241 ccctgaaggc actgttgtgt ccattctcat caagaggaca acaggggaac tgatgcctct
3301 cgcagttaga atgggaactc atgccacaat gaaaatccaa ggtagaacgg tgggtggtca
3361 aatgggcatg cttctcactg gctcaaacgc taaaagcatg gacctaggca caacaccagg
3421 tgactgtggg tgcccatata tatacaaaag aggcaatgac ttcgtggtca ttggggtgca
3481 cactgcagca gcccgtggag gcaacacggt catatgtgcc acacagggaa gtgaaggcga
3541 agccaccctc gaaggaggtg acaacaaggg cacctattgt ggagccccca tcttgggacc
3601 tggcaacgca ccaaaattaa gcacaaaaac aaaattctgg agatcttcca acgcgccgct
3661 tcctccaggt acctatgaac cagcatacct tggtggaaaa gacccgcgtg tgaagggagg
3721 cccatctcta caacaggtta tgagagacca acttaaacct tttacagagc caagagggaa
3781 gccaccaaaa ccaagtgtcc tagaatcagc aaagaagacc atcattaatg ttctggagca
3841 aaccattgac ccccctgaaa agtggtcata tgcccaagct tgtgcatccc tcgacaagac
3901 aacctccagt ggatacccgc atcacgtccg gaagaatgac tattggagtg gtgaatcctt
3961 cacagggaaa cttgcagacc aggcctcaaa agcaaacctt atgtatgagg aaggcaagca
4021 catgcaacca gtttacaccg cagcactcaa agacgagctt gtgaaaactg acaaaattta
4081 tggcaagatc aagaaaagac tcctgtgggg ctctgaccta tctaccatga ttcgatgcgc
4141 cagggcattt ggtggcctca tggatgagct caaagcaaat tgtatcacac tccctgtcag
4201 agttggtatg aacatgaatg aagatggtcc cataatattt gagaagcact ccaggtacag
4261 gtaccactat gatgctgatt actcccgctg ggattccaca caacagcggg cagtgctgga
4321 agcggcactt gaaatcatgg tgagattttc tgctgagcca cagttggcac aaatagtggc
4381 agaggacctg ctatcaccaa gtgtggttga tgtgggcgat ttcaaaattg ttatcaatga
4441 aggcctacct tctggcgtgc cttgcacttc acaatggaat tctattgccc actggttact
4501 caccctgtgt gccctgtctg aagtaacagg actaggccct gacatcatac aagccaactc
4561 catgtactct ttctatggtg atgatgagat tgtgagcaca gacataaaat tagacccaga
4621 gaaattgact gcaaaactca aagaatatgg tcttaaaccc acccggcctg acaagactga
4681 ggggccactg gtaattagtg aggacctgaa tgggttgact ttcctccgcc gaacagtcac
4741 ccgcgatcca gcgggttggt ttggaaagtt ggaccaaaac tccatcctca ggcagctgta
4801 ctggacaagg ggacccaacc atgaagaccc cagtgagact atgataccac acgcacagag
4861 acctgtgcag ctcatggcac tgctaggaga gtcctcccta catggaccct cattttacag
4921 caaggttagc aagctggtca tatctgaact taaagaggga ggaatggatt tttatgtgcc
4981 cagacaagag tcaatgttca ggtggatgag gttctcagat ctaagcacat gggagggcga
5041 tcgcaatctg gctcccagtt ttgtgaatga agatggcgtc gaatgacgcc gctccatcta
5101 atgatggtgc tgctggtctc gtaccagagg gcaataacga gacccttccc ctagaaccag
5161 ttgcgggcgc agctatagcc gcacccgtca ctggccaaaa caatataatt gacccctgga
5221 ttagaacaaa ttttgtgcaa gcaccaaatg gagagttcac agtgtcaccc agaaactctc
5281 ctggagaaat tttactaaac ctagagttgg gccctgattt gaacccttat ttggctcatt
5341 tgtcaaggat gtacaatggg tacgctggtg gagttgaagt ccaggttctc ctggcaggga
5401 acgcgttcac tgccgggaag atcctcttcg ccgctgtccc gccaaatttc ccagtggaat
5461 tcttaagccc agcccagatt acaatgctcc cacatataat agtagatgtt agaactcttg
5521 aaccaattat gatcccatta cctgatgtta ggaacacatt cttccactat aacaaccagc
5581 ccaacagccg catgagatta gtggctatgc tctacacccc ccttagatct aatggctcag
5641 gtgatgatgt tttcactgtt tcttgcaggg ttttgactag acctactcct gattttgagt
5701 tcacttactt agtgccaccc tctgttgaat ctaagactaa gcccttttcc ttacccattt
5761 taaccctttc tgagctcaca aattcgaggt tcccggtccc cattgattcg cttttcaccg
5821 cccagaacaa tgtgttgcag gtgcagtgtc aaaatggcag gtgcacactt gacggtgagc
5881 tacaaggcac aacccagttg ctcccatctg gcatctgtgc gttcagagga cgggtgacag
5941 cagaaactga caatcctgat aagtggcaca tgcaactgca aaacctcaat ggcacaacgt
6001 atgacccaac tgatgatgtg ccagccccac tgggtacacc tgacttcaag ggcgtcgtgt
6061 ttgggatggc aagccaaaga aatgtgggta acgatgcgcc cggctcaacc agggctcatg
6121 aggcggtgat ttcaacctac agccccagat ttgttcccaa attaggctct gtcaatttta
6181 aaagtaatga cgatgatttc caattgcagc caacaagatt cacaccagtg ggcatcaatg
6241 atgatggcaa ccacccgttc agacaatggg aactgccaga ctattcaggg gtgcttacct
6301 tgaatatgaa ccttgccccc ccggttgctc caaatttccc tggtgaacaa ttattactct
6361 tcagatcttc cgtgccatgt tcaggaggtt acaaccaagg tattatagat tgtcttatcc
6421 cccaagaatg gatccaacat ttctaccagg aatcagcacc ttctcagtca gaagtggccc
6481 tgatcaggta cgtcaacccc gacacgggtc gcacactgtt tgaggcaaaa ttgcacagat
6541 ctggctatat cactgtggct cactctggag actatcctct cgttgttccg gctaatggat
6601 actttagatt tgactcttgg gtaaatcagt tttactcact cgccccaatg ggaactggga
6661 atgggcgaag gagggctcag taatggctgg agctttcatt gcaggattgg cgggtgacat
6721 gctcacgtca tccgtgggct ccctggtgaa cgcaggggca aacgccatca gccaaaagat
6781 agactttgaa aacaacaaac aactccagtc tgcttccttt caacatgata aagagatgct
6841 ccaagcgcag gtaaatgcaa ccaagcagct gcaatctgag atgatagccc taaaacaggg
6901 ggttttggcc gcaggcggct tttcccccac tgatgcagcg aggggggcca tcggtgcacc
6961 catgacaaag gtgcttgact ggtctggcac tcgatattgg gctcccaatt ccacaaagac
7021 aactggttat tcggggcaat tcacctcttc acctgtgcac atgcccagcc cgagtgctcc
7081 acaatcaaaa cccgcaaagt ccagatctct aggttcttct tcttcttcta gtagtgttta
7141 tagtatgtct acccaatcaa cttctctaac atctggctct tctagcaatg cttcttctgc
7201 ttctacaaaa ttgacaaatt taggctctgg ctcctctcga aacaggacag cagagtgggt
7261 gaaccaacag agaagtctca gccctttcat gagtggcgca ctcaatatct cacatgtcac
7321 gccaccttca agtagggcct ccagttctgg gacggtctca accgtgccca aggaagtttt
7381 ggactcctgg acatctgcat tcaacacacg cagacagccg ctcttcgcac acctcagagt
7441 gaggggggag tcacgtgttt agtgaaaaga aataattggc tataatatga ttt
//