Typing tool
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Typing tool
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Complete norovirus genomes
| PQ336847 | GII.17 | |
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| GII.P17 |
ORF1: 1..5086
ORF2: 5067..6686
ORF3: 6686..7465
LOCUS PQ336847 7496 bp RNA linear VRL 22-OCT-2024
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/WT-NORO-0787/2016/UK
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PQ336847
VERSION PQ336847.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7496)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7496)
AUTHORS Roy,S., Williams,R.J., Tutill,H.J., Wong,S., Celma,C. and Breuer,J.
TITLE Direct Submission
JOURNAL Submitted (17-SEP-2024) Division of viral diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7496
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/WT-NORO-0787/2016/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Mar-2016"
/note="genotype: GII.17[P17]"
gene <1..5086
/gene="ORF1"
CDS <1..5086
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XGX96721.1"
/translation="SVAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGARPKQPPPGE
TKQTQKPPRPSTPELVKKIPPPPPNGEYEPKIAYKVGEGVSGLPDLTTVAQPDAQNTA
YSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAKIE
LTPLSLYWRVVYTPQYLIAPETLKNLSGETFPYTAFDNNCYAFCCWVLDLNDSWLSRR
MIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDIIGKLRPLN
ILNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAVEL
VPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKEEA
NELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASP
DIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVA
STLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLN
CDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDF
PGQPDMWKDHYRPDFAHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGLLH
ERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQ
AIKNISIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHLRSARIR
YYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPVEEGDEPEDKGGCPKPRD
EDDLTIDSKDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIE
EYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEI
RKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFIT
STHVIPKGITEAFGVPMNQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSI
LIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPY
IYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAP
KLSTKTKFWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPP
KPNVLESAKRTIINVLEQTIDPPERWSYAQACASLDKTTSSGYPHHVRKNDYWSGESF
TGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKLYGKIKKRLLWGSDLSTMIR
CARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQR
AVLEAALEIMVRFSAEPQLAQVVAEDLLSPSVVDVGDFKIAINEGLPSGVPCTSQWNS
IAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLK
PTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDP
SETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRW
MRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..976
/gene="ORF1"
/product="p48"
mat_peptide 977..2074
/gene="ORF1"
/product="NTPase"
mat_peptide 2075..2611
/gene="ORF1"
/product="p22"
mat_peptide 2612..3010
/gene="ORF1"
/product="VPg"
mat_peptide 3011..3553
/gene="ORF1"
/product="Pro"
mat_peptide 3554..5083
/gene="ORF1"
/product="RdRp"
gene 5067..6686
/gene="ORF2"
CDS 5067..6686
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGX96722.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGV
ASQRNVGNDAPGSTRAHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DDSNHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSYVPCSGGYNQGIIDC
LIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVV
PANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6686..7465
/gene="ORF3"
CDS 6686..7465
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGX96723.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVKATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTRVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPNASQSKPAKPRSLAPSSSSSGVYSMPTQLT
SLTSSSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPYMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 ttccgttgcc gttgctggca aaaacaacaa caacgacaag gaaaaatctt caagtgacag
61 cttgttttct aacatgactg ttacttttaa gaaagccctc ggggcgcggc ctaaacagcc
121 gcccccggga gaaacaaaac aaacacaaaa accaccaagg ccatcgacac cggaattggt
181 gaagaaaata cccccacccc cacccaatgg cgagtatgaa ccaaagatag cgtataaggt
241 gggagagggc gtgtccgggc tgcccgacct aacaaccgtg gcacagcctg acgcacagaa
301 cacagcctat agtgttcccc cactcagcca gagagaggtc ggcgaagcta aagaaccgtt
361 gcctggctcc attctggaaa tgtgggatgg tgagatctac cactatgggc tgtatgttga
421 gcgggggcac gtactcggag tacacaaacc acctgctgca ataagccttg ccaaaattga
481 attaacaccg ctgtctctct actggagagt ggtttacact ccccagtatt tgatagctcc
541 agaaactctt aagaacttaa gtggagagac tttcccatat acggcctttg acaacaactg
601 ttatgccttc tgttgttggg tcctagacct caacgactcc tggcttagca ggagaatgat
661 ccaaagaaca actggattct tcagaccgta tcaggattgg aacagaaaac ccttgccaac
721 catggatgaa ccgaaaatca agaaggccgc gaacgctgtt ctgtgtgctc tctcctcact
781 cttcactaga cccattaagg acatcattgg aaagctcaga ccactgaaca ttcttaatat
841 actggcaact tgtgattgga cttttgcggg aatagtggaa tccatgatcc ttcttgctga
901 actctttggg gtgttctgga cccccccaga tgtgtctgcg atgattgctc ccttactcgg
961 tgactacgag atgcaaggcc ccgaagacct ggccgtggaa cttgtgcccg tggtaatggg
1021 aggaataggt ttggtgttag gattcaccaa ggaaaagatc ggcaagatgc tttcatcagc
1081 tgcgaccaca cttagggcct gtaaggatct aggatcttat gggttggaga tactcaaatt
1141 ggtcatgaag tggttcttcc ccaagaagga ggaggctaac gaattagcca tggtgagggc
1201 cattgaggat gcagtcctgg atttggaggc aatagaaaac aatcacatga ccacccttct
1261 caaggacaaa gacagcctgg ccacatacat gagaactctt gacttggaag aagagaaagc
1321 aaggaagctg tcaaccaaat cggcgtcacc tgacatcgtg ggcacaataa acgcattgtt
1381 ggcaaggata gcagccgcca ggtcactggt ccacaaggct aaggaggagc tctcgagcag
1441 acagagacct gttgttgtaa tgatatcagg tagaccaggt ataggaaaga cccatctggc
1501 cagagagcta gccaagaaag ttgcgtcaac actgtcaggc gatcaaagga ttggactgat
1561 acctagaaat ggcgtcgacc attgggacgc ctataaagga gagagggtgg ttctgtggga
1621 cgattatggc atgagcaacc ctatacagga cgcactgagg cttcaagaat tggctgacac
1681 ctgtcctctg accctaaatt gtgacaggat tgaaaacaaa ggaaaagtgt tcgacagtga
1741 tgccataatc ataacaacca accttgcaaa cccagcacca ctggactatg tcaactttga
1801 ggcctgttct agacgcatag acttcttggt gtatgcagac gcacctgaca tcgagaaggc
1861 taagcgtgat ttccctggcc aaccagatat gtggaaagac cattacagac cagacttcgc
1921 acacatcaaa cttcagctgg caccacaggg aggctttgac aaaaatggca acaccccaca
1981 tggcaaaggt gtggtaaagt ctctgacgat tggttctctg atcgccaggg cttctggctt
2041 gctccacgag agaatggatg aattcgagct ccaaggctct gacctgccga ccttcaattt
2101 cgaccgcaac aaagtcgccg ccttcagaca attagcagct gaaaacaaat atggtcttat
2161 ggacacactg agggtcggta accaactgaa aagtgtcaaa accctggacg agctgaagca
2221 ggccataaag aacatcagta tcaagaagtg ccagatagtg tataatgggt gcacctacac
2281 catggaatct gatgggagga acaaggttgt ggttgaaaag gttcaaaatg caacagtcca
2341 aaccaacaat gaacttgcag gagcactcca ccacctgaga tctgcaagga taagatatta
2401 tgttaaatgt ttccaagaag ctatttactc cctactccaa attgctggtg cagccttcgt
2461 cacctcacgc atcgtgaggc gcatgaatat ctcaaacctt tggtcgaagc cacccgtcga
2521 ggagggtgat gagcctgaag acaaaggagg atgccccaag cccagggatg aagatgacct
2581 cactattgac tctaaagaca ttaaagtgga agggaagaag ggcaagaaca aatctggccg
2641 gggcaagaaa cacacagctt tctcatccaa gggcctcagt gatgaagagt acgatgagta
2701 caagaggatt agagaggaga ggaatggcaa atactcaata gaggaatacc tccaagatag
2761 ggatagatac tatgaagagc ttgccattgc taaggccact gaggaagact tctgtgaaga
2821 ggaggaaatc aagattcgcc agagaatctt ccgacccacc agaaagcagc ggaaagagga
2881 aagggccacg cttgggcttg tcacaggatc ggagatcaga aagaggaatc cagatgactt
2941 taaaccaaaa ggaaaattgt gggctgatga caacaggagt gtggactaca atgagaggat
3001 agattttgag gctcccccga gtgtttggtc caggatagtc aactttggta caggatgggg
3061 attctgggtt tctccaagtc tctttataac ttcaacacac gtcataccaa aaggaatcac
3121 tgaggccttt ggagtgccca tgaaccaaat ccaaattcac aaatctggag aattttgccg
3181 cttgcggttt ccaaaaccaa tcagaccaga cgtgagtggg atgatcttgg aagagggtgc
3241 ccctgaaggc actgttgtgt ccattctcat caagaggaca acaggggagc tgatgcctct
3301 cgcagtcaga atggggactc atgccacaat gaaaatccaa ggtagaacgg tgggtggtca
3361 gatgggtatg cttctcactg gctcaaatgc taaaagcatg gatctaggca caacaccagg
3421 tgactgtggg tgcccataca tatacaaaag gggcaatgac tttgtggtca ttggggtgca
3481 cactgcagca gctcgtgggg gcaacacggt catatgtgcc acacagggaa gtgaaggtga
3541 agccactctc gaaggaggtg acaacaaggg tacctattgt ggagccccca ttttgggacc
3601 tggcaatgca ccaaaattga gcacaaagac aaaattctgg aggtcttcca atgcaccgct
3661 tcccccaggt acttatgaac cagcatacct tggtggaaga gacccgcgtg tgaagggagg
3721 cccatctctg caacaggtca tgagagacca acttaaacct tttacagagc ccagagggaa
3781 gccaccaaaa ccaaatgtcc tagagtcagc aaagaggact atcatcaatg ttctggaaca
3841 aaccattgac ccccctgaaa gatggtcata tgcccaagct tgtgcatccc tcgacaagac
3901 aacctccagt ggatacccgc accacgtccg gaagaatgac tattggagtg gtgaatcctt
3961 cacggggaaa cttgcagacc aggcctcaaa agcaaatctc atgtatgagg aaggcaagca
4021 catgcaacca gtttacaccg cagcgctcaa agacgagctc gtgaaaactg acaaacttta
4081 tggcaagatc aagaaaaggc tcctgtgggg ttctgaccta tccaccatga ttcgatgcgc
4141 cagagcattt ggtggtctca tggatgagct caaagcaaat tgtattacac tccctatcag
4201 agttggtatg aacatgaatg aggatggtcc cataatattt gaaaaacact ccaggtatag
4261 gtaccactat gatgctgatt actcccgctg ggactccaca cagcagcggg cagtgctaga
4321 agcggcactt gaaatcatgg tgagattttc tgctgagcca cagctagcac aagtggtggc
4381 agaggacctg ctgtcaccaa gtgtggttga tgtgggcgac ttcaaaattg ctatcaatga
4441 aggcctacca tctggcgtgc cttgcacctc acaatggaat tctattgccc actggttact
4501 caccctgtgt gccctgtctg aagtaacagg actaggtcct gacatcatac aagccaactc
4561 catgtactct ttctatggtg atgatgagat tgtgagcaca gacataaaat tggacccaga
4621 gaaattgact gcaaagctca aagaatatgg tcttaaaccc actcggcctg ataaaactga
4681 ggggccgctg gtgattagtg aagacctgaa tgggttgact ttcctccgcc gaacagtcac
4741 ccgcgatcca gcaggttggt ttggaaagct ggaccaaaac tccatcctca ggcagctgta
4801 ctggacaaga ggacccaacc atgaagaccc cagtgagact atgataccac acgcacagag
4861 acctgtacag cttatggcac tactaggaga atcctcccta catggtccct cattttacag
4921 caaggttagc aagctggtca tatctgaact taaagaggga ggaatggatt tttatgtgcc
4981 cagacaagag tcaatgttca gatggatgag gttctcagat ctaagcacat gggagggcga
5041 tcgcaatctg gctcccagtt ttgtgaatga agatggcgtc gaatgacgcc gccccatcta
5101 acgatggtgc tgctggtctc gtaccagagg gcaacaacga gacccttccc ctagaaccag
5161 ttgcgggcgc agctatagcc gcacccgtca ctggccaaaa caacataatt gacccctgga
5221 ttagaacaaa ttttgtgcaa gcaccaaatg gagagttcac agtgtcaccc agaaactctc
5281 ctggagaaat tttactaaac ctagagttgg gccctgattt gaacccttat ttggctcatt
5341 tgtcaaggat gtacaatggg tatgctggtg gagtggaagt tcaggttctc ctggcgggga
5401 acgcgttcac tgccggaaag attctcttcg ccgccgtccc gccaaatttc ccagtggaat
5461 tcttgagccc agcccagatt acaatgctcc cacatataat agtagatgtt aggactcttg
5521 aaccaatcat gatcccacta cctgatgtta ggaatacatt cttccattat aataaccagc
5581 ccaacagccg catgagatta gtggctatgc tctacacccc ccttagatct aatggctcag
5641 gtgatgatgt ttttactgtt tcttgtaggg ttttgactag gcctactcct gattttgagt
5701 tcacttattt agtgccacct tctgttgagt ctaagactaa gcctttttcc ttacccattc
5761 taaccctttc tgagctcaca aattcgaggt tcccagtccc catcgattca cttttcaccg
5821 cccagaataa tgtgttgcag gtacagtgtc aaaatggcag gtgcacactt gatggtgagt
5881 tacaaggtac aacccagttg ctcccatctg gcatctgtgc attcagagga cgggtgacag
5941 cagaaactga caatcctgac aagtggcaca tgcaactaca aaacctcaat ggcacaacat
6001 atgacccaac tgatgacgtg ccagccccac tgggtacacc tgacttcaag ggcgtcgtgt
6061 ttggggtagc aagccaaaga aatgtgggta acgatgcgcc tggctcaacc agggcccatg
6121 aggcggtgat ttcgacctat agccccagat ttgtccctaa attaggctct gtcaatttta
6181 aaagtaatga tgatgatttc caattgcagc cgacaagatt cacaccagtg ggcatcaatg
6241 atgatgatag taaccacccg ttcagacaat gggaactacc agactattca ggggtgctta
6301 cattgaatat gaaccttgcc cccccggttg ctccaaattt ccctggtgaa caattattat
6361 tcttcagatc ttacgtgcca tgttcaggag gttataacca aggcattata gattgtctta
6421 ttccccaaga atggatccaa cacttctatc aggaatcagc accctcccag tcagacgtgg
6481 ccctgatcag gtatgtcaac cccgacacgg gacgcacact gtttgaagca aaattgcacc
6541 gatctggcta tattactgtg gctcactctg gagattatcc tcttgttgtt ccggctaatg
6601 gatactttag atttgattct tgggtaaatc aattttactc actcgcccca atgggaactg
6661 ggaatgggcg aaggagggct cagtaatggc tggagctttc attgcaggat tggcaggcga
6721 catgctcacg tcatctgtgg gctccctggt gaacgcaggg gcaaacgcca tcaaccaaaa
6781 gatagatttt gaaaacaaca aacaactcca gtctgcttcc tttcagcatg ataaagagat
6841 gctccaagcg caggtgaagg caaccaagca gctgcaatct gaaatgatag ccctaaaaca
6901 gggggttttg gccgcaggcg gcttttcccc cactgatgca gcaaggggag ccatcggtgc
6961 acccatgaca agggtgcttg actggtctgg cactcgatat tgggcaccca attccacaaa
7021 aacaactggt tattcggggc aattcacctc ttcacctgta catatgccta gcccaaatgc
7081 ttcacaatca aaacccgcaa aacccaggtc tctagctcct tcttcttctt ctagtggtgt
7141 ttatagtatg cctactcaat taacttctct aacatctagc tcttctagta atgcttcttc
7201 tgcctctaca aaattgacaa atttaagctc tggctcctct caaaacagga cagcagagtg
7261 ggtgaaccaa cagagaagtc ttagccctta catgagtggc gcactcaata tctcacatgt
7321 tacgccaccc tcaagtaggg cctccagttc tgggacggtc tcgaccgtgc ccaaggaagt
7381 tttggactcc tggacatctg cattcaacac acgcagacag ccgctcttcg cacacctcag
7441 agtgaggggg gagtcacgtg tttagtgaaa agaaataatt ggctataata tgattt
//