Typing tool
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Typing tool
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Complete norovirus genomes
| PQ310234 | GII.17 | |
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| GII.P17 |
ORF1: 1..5109
ORF2: 5090..6706
ORF3: 6706..7485
LOCUS PQ310234 7556 bp RNA linear VRL 17-OCT-2024
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/Park0001/2024/USA
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION PQ310234
VERSION PQ310234.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7556)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7556)
AUTHORS Rowley,C., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (11-SEP-2024) Viral Gastroenteritis Branch, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. v. 11.1.2; SPAdes v. v. 3.6
Sequencing Technology :: Sanger dideoxy sequencing; Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7556
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/Park0001/2024/USA"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="11-Jan-2024"
/note="genotype: GII.17[P17]"
gene 1..5109
/gene="ORF1"
CDS 1..5109
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XGR28075.1"
/translation="MKMASNDASAAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGAR
SKQPPPGETKQTPRPPRPPTPELVKKIPPPPPNGEDEPKVVYKVGEGVSGLPDLTTVA
QPDAQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPA
AISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLSGETFPYTAFDNNCYAFCCWVLDL
NDSWLSRRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDV
IGKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLIMKW
FFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARK
LSSKSASPDIVGTVNALLARIAAARSLVHKAREELSSRQRPVVVMLSGRPGIGKTHLA
RELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPD
IEKAKRDFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLI
ARASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSV
KTLDELKQAIKNIAIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALH
HLRSARIRYYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDK
GGCPKPRDEDDLTIDSKDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATL
GLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFW
VSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGA
PEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRDNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAP
ILGPGNAPRLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKN
DYWSGESFTGKLADQASKANLMFEEGKHMQPVYTAALKDELVKTDKIYGQIKKRLLWG
SDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPERLTA
KLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWT
RGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVP
RQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 1..999
/gene="ORF1"
/product="p48"
mat_peptide 1000..2097
/gene="ORF1"
/product="NTPase"
mat_peptide 2098..2634
/gene="ORF1"
/product="p22"
mat_peptide 2635..3033
/gene="ORF1"
/product="VPg"
mat_peptide 3034..3576
/gene="ORF1"
/product="Pro"
mat_peptide 3577..5106
/gene="ORF1"
/product="RdRp"
gene 5090..6706
/gene="ORF2"
CDS 5090..6706
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGR28076.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGDHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6706..7485
/gene="ORF3"
CDS 6706..7485
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGR28077.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGILVAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQPKPAKPRSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gccgttgctg gcaaaaacaa caacaacgac
61 aaggaaaaat cttcaagtga cagcttgttt tccaacatga ctgttacttt taagaaagcc
121 ctcggggcgc ggtctaagca gccgcccccg ggagaaacaa aacaaacgcc aagaccacca
181 aggccgccga caccggaatt ggtgaagaag atacccccac ccccccccaa tggcgaggat
241 gagccaaagg tagtgtataa ggtgggagaa ggtgtgtctg ggctgcccga cttaacaacc
301 gtggcacaac ctgacgcaca gaacacagcc tacagtgtcc ccccacttag ccagagagag
361 gtcggcgaag ctaaagaacc gttgcctggc tccattctgg aaatgtggga tggtgagatc
421 taccactatg ggctgtatgt tgagcggggg catgtactgg gagtgcacaa accacctgcc
481 gcaataagcc ttgccaaaat tgaattaaca ccgctgtctc tctactggag agtagtttac
541 actccccagt acttgatagc tccagagacc cttaagaact taagtggaga gactttccca
601 tacacggcct ttgacaacaa ctgttatgcc ttctgttgtt gggttttaga tctcaacgac
661 tcctggctta gcagaagaat gatccaaaga acaaccggat tcttcagacc gtaccaggac
721 tggaacagaa aacccctgcc aaccatggat gaaccaaaaa tcaaaaaggc cgcgaatgct
781 gttctgtgtg ctctctcctc actcttcact aggcccatca aagatgtcat aggaaagctt
841 aaaccactga acattatgaa catactggca acttgtgatt ggacttttgc gggcatagtg
901 gaatccatga tccttcttgc tgagctcttt ggggtgttct ggacgccccc agatgtgtct
961 gcaataattg ctcccctact cggtgactac gagatgcaag gccccgaaga cctggccgtg
1021 gaacttgtgc ccgtggtaat gggaggaata ggtttggtgt taggattcac caaggaaaag
1081 atcggcaaga tgctttcatc agctgcgacc acactcaggg cttgtaagga tctaggatct
1141 tatgggttgg agatactcaa actgatcatg aagtggttct tccctaagaa ggaggaggcc
1201 aacgagttag ccatggtgag ggccattgag gatgcggttc tggatttaga ggcaatagaa
1261 aacaaccaca tgaccactct ccttaaggac aaagacagcc tggccacata catgagaact
1321 cttgacttgg aagaagaaaa agcaaggaaa ctgtcatcca aatcggcgtc acctgacatc
1381 gtgggcacag taaacgcatt gttggcaagg atagcagccg ccaggtcgct ggtccacaag
1441 gctagggagg agctctcgag cagacagagg cctgttgttg taatgctatc aggtagacca
1501 ggtataggaa agacccatct ggccagagag ctagccaaga aggttgcgtc aacgctgtca
1561 ggcgatcaaa ggattggact aatacctaga aatggcgtcg atcattggga cgcctacaaa
1621 ggagagcggg tggttctgtg ggatgactat ggcatgagta accctataca ggacgctctg
1681 aggctccaag aattggctga cacctgtcct ctgaccctaa attgtgacag gattgaaaac
1741 aaaggaaaag tattcgacag tgacgccata atcataacaa ccaaccttgc aaaccccgca
1801 ccactggatt atgtcaactt tgaggcttgt tccagacgca tagacttctt ggtgtatgca
1861 gacgcgcctg acatcgagaa ggctaagcgt gacttccctg gccaaccaga tatgtggaaa
1921 gaccattaca gatcagactt ctcacacatt aaacttcagc tggcaccaca gggaggcttt
1981 gataagaatg gcaacacccc acatggcaaa ggtgtggtta agtctctgac gattggttct
2041 ctgatcgcca gggcttctgg cttgctccat gagagaatgg acgaattcga gctccaaggt
2101 tctgacttac caaccttcaa tttcgaccgt aacaaagtcg ccgccttcag acaattggca
2161 gctgaaaaca aatatggtct tatggacaca ctgagggtcg gcaaccaact gaaaagtgtc
2221 aaaaccctgg atgagctgaa gcaggctata aagaacatcg ccatcaagaa gtgccagata
2281 gtgtacaatg gatgcaccta caccatggaa tctgatggta ggaataaggt tgtggttgaa
2341 aaggttcaaa atgcaacagt ccaaaccaat aatgaacttg caggagcact ccaccacctg
2401 agatctgcaa ggataaggta ttatgtcaaa tgtttccaag aagctattta ttctctactc
2461 caaattgctg gtgcggcctt cgtcaccaca cgcatcgtga ggcgcatgaa catctcaaac
2521 ctctggtcga agccacccgt cgaagagggt gatgagcctg aagacaaagg ggggtgcccc
2581 aagcccaggg atgaagatga cctcactatt gactccaaag acattaaaac agaagggaag
2641 aagggcaaga acaaatctgg ccggggcaag aaacacacag ctttctcatc caagggcctc
2701 agtgatgaag agtacgatga gtacaagaga atcagggagg agaggaatgg caaatactca
2761 atagaggaat acctccagga tagggataga tactatgaag agcttgccat tgctaaggcc
2821 actgaggaag acttctgtga agaggaggaa atcaaaattc gccagagaat cttccggccc
2881 accaggaagc aacggagaga ggaaagagcc acgctcgggc ttgtcacagg atcggaaatc
2941 agaaagagga atccagatga ctttaagcca aaaggaaagt tgtgggctga tgacaacaga
3001 agtgtggact acaatgagag gatagatttt gaggctcccc cgagtgtttg gtctaggata
3061 gtcaactttg gtacaggatg gggattctgg gtctccccaa gtctctttat aacttcaaca
3121 catgtcatac caaaagggat cactgaggct tttggagtcc ccattaacca aattcaaatt
3181 cacaaatctg gagagttttg ccgcttgcgg tttccaaaac caatcagacc agacgtgagt
3241 ggaatgatct tggaagaggg tgcccctgaa ggcacagttg tgtccattct catcaagagg
3301 acaacagggg aactgatgcc tctcgcagtc agaatgggaa ctcatgccac aatgaaaatc
3361 caaggtagaa cggtgggcgg tcaaatgggc atgcttctca ctggctcaaa cgctaaaagc
3421 atggacctag gcacaacacc aggtgactgt gggtgcccat acatatacaa aagggacaat
3481 gacttcgtgg tcattggggt acacactgcg gcagcccgtg gaggcaacac ggtcatatgt
3541 gccacacagg gaagtgaagg cgaagccacc ctcgaaggag gtgacaacaa gggcacctat
3601 tgtggagccc ccatcttggg acctggcaac gcaccaagat tgagcacaaa aacaaaattc
3661 tggagatctt ctaacgcgcc gcttcctcca ggcacctatg aaccagcata ccttggtgga
3721 aaagacccgc gtgtgaaggg aggcccatct ctacaacagg ttatgagaga ccaactcaaa
3781 ccttttacag agcctagggg gaagccacca aaaccaagtg tcctagaatc agcaaagaag
3841 actatcatca atgttctaga acaaaccatt gacccccctg aaaagtggtc atatgcccaa
3901 gcttgtgcat ccctcgacaa gacaacctcc agtggatacc cccatcatgt ccggaagaat
3961 gattattgga gtggcgaatc cttcacgggg aaacttgcag accaggcctc aaaagcaaac
4021 cttatgtttg aggaaggcaa gcacatgcaa ccagtttaca ctgcagcact caaagacgag
4081 ctcgtgaaaa ctgacaaaat ttatggccag atcaagaaaa gactcctgtg gggctctgac
4141 ctatccacca tgattcgatg cgccagggca tttggtggcc tcatggatga gctcaaggct
4201 aattgtatca cactccctat cagggttggt atgaacatga atgaggatgg tcccataata
4261 tttgaaaagc actccaggta caggtaccat tatgatgctg attactcccg ctgggattcc
4321 acacaacagc gggcagtgct ggaagcggca cttgaaatca tggtgagatt ttctgctgag
4381 ccacagttgg cacaaatagt ggcagaggac ctgctatcac caagtgtggt tgatgtgggc
4441 gatttcaaaa ttactatcaa tgaaggccta ccatctggcg tgccctgcac ttcacaatgg
4501 aattccattg cccactggtt actcaccctg tgtgccctgt ctgaagtaac aggactaggc
4561 cctgacatca tacaagccaa ctccatgtac tctttttatg gtgatgatga aatagtgagc
4621 acagacataa aattagaccc agagagattg actgcaaaac tcaaagaata tggtcttaaa
4681 cccacccggc ctgataagac tgaggggcca ttggtaatta gtgaggacct gaatgggttg
4741 actttcctcc gccgaacagt cacccgcgat ccagcgggtt ggtttggaaa gttggaccaa
4801 aactccatcc tcaggcagct gtactggaca aggggaccca accatgaaga ccccagtgag
4861 accatgatac cacacgcaca gagacctgtg cagctcatgg cactgctagg agagtcctcc
4921 ctacatggac cctcatttta cagcaaggtt agcaagctgg tcatatctga actcaaagag
4981 ggaggaatgg atttttatgt gcccagacaa gagtcaatgt tcagatggat gaggttctca
5041 gatctaagca catgggaggg cgatcgcaat ctggctccca gttttgtgaa tgaagatggc
5101 gtcgaatgac gccgctccat ctaatgatgg tgctgctggt ctcgtaccag agggcaataa
5161 cgagaccctt cccctagaac cagttgcggg cgcagctata gccgcacccg tcactggcca
5221 gaacaatata attgacccct ggattagaac aaattttgtg caagcaccaa atggagagtt
5281 cacagtgtca cccagaaact ctcctggaga aattttacta aacttagagt tgggccctga
5341 tttgaaccct tatttggctc atttgtcaag gatgtacaat gggtatgctg gtggagttga
5401 agtccaggtt ctcctggcgg ggaacgcgtt cactgccggg aagatcctct tcgccgctgt
5461 cccgccaaat ttcccagtgg aattcttaag cccagcccag attacaatgc tcccacatat
5521 aatagtagat gttaggactc ttgaaccaat aatgatccca ttacctgatg ttaggaacac
5581 attcttccac tataataacc agcccaacag ccgcatgaga ttagtggcta tgctctatac
5641 cccccttaga tctaatggct caggtgatga tgttttcact gtttcttgca gggttttgac
5701 taggcccact cctgattttg agttcactta tctagtgcca ccctctgttg aatctaagac
5761 caaacccttt tccttaccca ttctaaccct ttctgagctt acaaattcga ggttcccggt
5821 ccccattgat tcgcttttca ccgcccagaa caatgtgttg caggtgcagt gtcaaaatgg
5881 caggtgcaca cttgacggtg agctacaagg cacaacccag ttgctcccat ctggtatctg
5941 tgcgttcaga ggacgggtga cagcagaaac tgacaatcct gacaagtggc acatgcaact
6001 gcaaaacctc aatggcacaa catatgatcc aactgatgat gtgccagccc cactgggtac
6061 acctgacttc aagggcgtcg tgtttggaat ggcaagccaa agaaatgtgg gtaacgatgc
6121 gcccggctca accaggtccc atgaggcggt aatttcaacc tacagcccca gattcgttcc
6181 aaaattaggc tctgtcaatt ttaaaagtaa tgacgatgat ttccaattgc agccaacaag
6241 attcacacca gtgggcatta atgatgatgg cgaccacccg ttcagacagt gggaattgcc
6301 agactattca ggggtgctta ccttgaatat gaaccttgcc cccccggttg ctccaaattt
6361 ccctggtgaa caattattat tcttcagatc ttctgtgcca tgttcaggag gttacaacca
6421 aggtattata gattgtctta tcccccaaga atggatccaa cacttctacc aggaatcagc
6481 accttcccag tcagacgtgg ccctgatcag gtacgtcaac cccgacacgg gtcgcacact
6541 gtttgaggca aaattgcata gatctggcta tattactgtg gctcactctg gagactatcc
6601 tcttgttgtt ccggctaatg gatactttag atttgactct tgggtaaatc agttttactc
6661 actcgcccca atgggaactg ggaatgggcg aaggagggct cagtaatggc tggagctttc
6721 attgcaggat tggcgggtga catgctcacg tcatccgtgg gctccctggt gaacgcaggg
6781 gcaaacgcca tcaaccaaaa gatagacttt gaaaacaaca aacaactcca gtctgcttcc
6841 tttcaacatg acaaagagat gctccaagcg caggtgaacg caaccaagca gctgcaatct
6901 gagatgatag ccctaaaaca ggggattttg gtcgcaggcg gcttttctcc cactgatgca
6961 gcgagggggg ccatcggtgc acccatgaca aaggtgcttg actggtctgg cactcgatat
7021 tgggctccca attccacaaa gacaactggt tattcggggc aattcacctc ttcacctgtg
7081 cacatgccca gcccgagtgt tccacaacca aaacccgcaa agcccaggtc tctaggttcc
7141 tcttcttctt ctagtagtgt ttatagtatg tctacccaat taacttctct aacatctggc
7201 tcttccagta atgcttcttc tgcttctaca aaattgacga atttaagttc cggctcctct
7261 caaaacagaa cagcagagtg ggtgaaccaa cagagaagtc tcagcccttt catgagtggc
7321 gcactcaata tatcacatgt cacgccacct tcaagtaggg cctctagttc tgggacggtc
7381 tcaaccgtgc ccaaggaggt tttggactcc tggacatctg cattcaacac acgcagacag
7441 ccgctcttcg cacacctcag agtgaggggg gagtcacgtg tttagtgaaa agaaataatt
7501 ggctataata tgatctcttt aaaatttaaa tttggctaat ttgtatcttt taaaaa
//