Typing tool
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Typing tool
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Complete norovirus genomes
| PQ310125 | GII.17 | |
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| GII.P17 |
ORF1: 1..5109
ORF2: 5090..6715
ORF3: 6715..7494
LOCUS PQ310125 7545 bp RNA linear VRL 15-DEC-2025
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/Oregon7112/2023/USA
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION PQ310125
VERSION PQ310125.2
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7545)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
PUBMED 39328162
REFERENCE 2 (bases 1 to 7545)
AUTHORS Tsaknaridis,L., Barclay,L., Montmayeur,A.M., Vinje,J. and
Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (11-SEP-2024) Viral Gastroenteritis Branch, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT On Dec 15, 2025 this sequence version replaced PQ310125.1.
##Assembly-Data-START##
Assembly Method :: Geneious v. v. 11.1.2; SPAdes v. v. 3.6
Sequencing Technology :: Sanger dideoxy sequencing; Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7545
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/Oregon7112/2023/USA"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="09-Aug-2023"
/note="genotype: GII.17[P17]"
gene 1..5109
/gene="ORF1"
CDS 1..5109
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YCB08525.1"
/translation="MKMASNDASAAVAGKNNNNDKEKSSSDNLFSNMTVTFKKALGAR
SKQPPPGEVKQIQRPPRPPTPELVKRIPPPPPNGENEPQIVYKVGEGVSGLPDLTTVA
RPDTQDTAYSVPPLSQREAGEAKEPLPGSILEMWDGEIYHYGLYVERGNVLGVHKPPA
AVSLAKIELTPLSLYWRVVYTPQYLISPDTLKGLSGETFPYTAFDNNCYAFCCWVLDL
NDSWLSRRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDI
IGKLRPLNILNILATCDWTFAGIVESMILLAELFGVYWTPPDVSAMIAPLLGDYEMQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACRDLGSYGLEILKLVMKW
FFPKKEEASELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARK
LSTKSASPDIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLA
RELAKKVASTLSGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELA
DTCPLTLNCDRIENKGKVFDSDVIVITTNLANPAPLDYVNFEACSRRIDFLVYAEAPD
IEKAKRDFPGQPDMWKDHYRPDFTHIKLQLAPQGGFDKNGNTPHGKGVMKSLTVGSLI
ARASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENRYGLMDTLRVGNQLKSV
KTLDELKQAIKNISIKKCQIVYNGCTYTMESDGRGKVVVEKVQNATVQTNNELTGALH
HLRSARIRYYVKCFQEAIYSLLQITGAAFVTSRIVKRMNISNLWSKPPVEEGDEPEDK
GGCPKPRDEDDLTIDSKDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATL
GLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFW
VSPSLFITSTHVIPKGITEAFGVPMNQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGA
PEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDFVAIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAP
ILGPGSAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPNPNVLESAKKTIINVLEQTIDPPQKWSYAQACASLDKTTSSGYPHHARKN
DYWNGETFTGKLADQASKANLMFEEGKHMQPVFTAALKDELVKTDKIYGKIKKRLLWG
SDLSTMIRCARAFGGLMDELKANCIALPVRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTA
KLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQIYWT
RGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVP
RQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 1..999
/gene="ORF1"
/product="p48"
mat_peptide 1000..2097
/gene="ORF1"
/product="NTPase"
mat_peptide 2098..2634
/gene="ORF1"
/product="p22"
mat_peptide 2635..3033
/gene="ORF1"
/product="VPg"
mat_peptide 3034..3576
/gene="ORF1"
/product="Pro"
mat_peptide 3577..5106
/gene="ORF1"
/product="RdRp"
gene 5090..6715
/gene="ORF2"
CDS 5090..6715
/gene="ORF2"
/codon_start=1
/product="VP1"
/protein_id="YCB08526.1"
/translation="MKMASNDAAPSNDGATGLVPEINTETLPLEPVAGASLAAAVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYNNRPSERMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTISELTNSRFPAPIDSLFTAQNNVLNVQCQNGRCTLDGELQGTT
QLLPTGICAFRGKITADVEHQHDDRWHLSLTNLNGTPFDPTEDVPAPLGTPDFTGLLF
GVASQRNVGGSGNNTTRAHEAVISTTSTQFVPKLGSVNFGSESDDFQVSQPTKFTPVG
IKIETGHPFEQWRLPNYAGALTLNMNLAPPIAPNFPGEQLLFFRSNIPCAGGISDGVI
DCLLPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRTGYITVAHTGDYPL
VVPSNGFFRFDSWVNQFYSLAPMGTGNGRRRIQ"
gene 6715..7494
/gene="ORF3"
CDS 6715..7494
/gene="ORF3"
/codon_start=1
/product="VP2"
/protein_id="YCB08527.1"
/translation="MAGAFIAGLAGDMLTNTVGSLANAGANAINQKIDFENNKQLQAA
SFQHDKDMLRAQVNATKQLQSDMIAIKQGILTAGGFSPTDAARGAVGAPMTKVLDWSG
TRYWAPNSTKTTSYSGQFTSTPVHTPNLSSKPKTTSVKSPSPSSSSGSVYSLATQSTS
LSGPSSGSSASSASTQSTKLSSTSSMSRTIDWVNQQRSLSPYMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gccgttgctg gcaaaaacaa caacaacgac
61 aaggaaaaat cttcaagtga caacttgttt tctaacatga ctgtcacttt taagaaagcc
121 ctcggggcgc ggtctaaaca gccgcccccg ggagaagtaa aacaaataca gagaccacca
181 agaccaccga caccggaatt ggtgaagaga atacccccac ccccacccaa tggcgagaat
241 gagccacaaa tagtgtacaa ggtgggggag ggtgtgtctg ggctacccga cctaacaacc
301 gtggcgcggc ctgacacaca agacacagct tatagtgttc ccccactaag ccagagagaa
361 gccggcgaag ctaaagaacc actgcctggt tccattcttg agatgtggga tggtgagatc
421 taccactatg ggctgtatgt tgaacgggga aatgtactcg gggtgcacaa accacctgct
481 gcagtaagcc tcgccaaaat tgaattaaca cctctgtctc tctactggag agtggtatac
541 actccccagt atctgatatc tccagacact cttaagggct tgagcggaga gactttccca
601 tacacggcct ttgataacaa ctgctatgcc ttctgttgtt gggtcctaga cctcaatgac
661 tcctggctca gcaggaggat gattcaaaga acaactggat ttttcagacc gtatcaggat
721 tggaacagaa agcccttgcc aaccatggat gagccgaaaa tcaaaaaggc cgcaaatgct
781 gtcctttgtg ctctctcctc actcttcacc aggcccatta aggatatcat tggaaaactc
841 aggccattaa acatcctcaa cattctggca acatgtgact ggacttttgc aggcatagtg
901 gaatccatga tccttcttgc tgaactcttt ggggtgtact ggactccccc agatgtgtct
961 gcgatgattg ctcccttact cggtgactac gaaatgcaag gccccgaaga cctggccgtg
1021 gaacttgtgc ccgtggtaat gggaggaata ggtttggtgt taggattcac caaagaaaag
1081 atcggcaaga tgctctcatc agctgcaacc acacttaggg cctgtagaga cctaggatct
1141 tatggactgg agatactcaa attggtcatg aagtggttct tccccaagaa ggaagaggct
1201 agtgaactag ctatggtgag ggccattgag gatgcagtcc tggatttgga ggcgatagaa
1261 aacaaccaca tgaccaccct cctcaaggac aaggatagcc tggccacata catgagaact
1321 cttgacttgg aagaagagaa agcaaggaaa ctatcaacca aatcggcatc acctgacatc
1381 gtgggcacaa taaacgcatt attggcaagg attgcagctg ctaggtcact ggtccacaag
1441 gccaaggagg agctctcgag cagacagagg cctgttgttg taatgatatc aggtagacca
1501 ggcataggaa agacccatct tgccagagag ctagccaaga aagttgcatc tacactgtca
1561 ggtgaccaaa gaattggatt ggtgcctaga aatggcgtcg atcactggga tgcctacaag
1621 ggagaaaggg tagtcctgtg ggatgactac ggtatgagca accctataca ggacgcattg
1681 aggcttcaag aattggctga tacctgccca ctaaccctaa attgtgacag gattgaaaac
1741 aaaggaaaag tgttcgacag tgatgtcata gtcataacaa ccaatcttgc aaacccagca
1801 ccactagact atgtcaactt tgaggcctgc tctagacgca tagacttctt ggtgtatgca
1861 gaagcacctg acatcgagaa ggctaagcgt gatttccctg gtcaaccaga tatgtggaaa
1921 gaccactata gaccagactt cacacacatt aaacttcaac tggcaccaca aggaggtttt
1981 gacaagaatg gtaacacccc acatggcaaa ggtgtgatga agtcactgac ggttggttct
2041 ctaatcgcaa gggcttctgg cttgctccat gaaagaatgg atgagtttga gctccagggc
2101 tctgacctgc caaccttcaa ctttgaccgt aacaaagtcg ccgccttcag acaattggca
2161 gctgaaaata gatatggtct tatggacaca ctgagggtcg gcaaccaact gaagagtgtc
2221 aaaaccctag atgagctgaa gcaggccata aagaacatca gcatcaagaa gtgccaaata
2281 gtgtataatg gctgtacata caccatggaa tctgatggga ggggcaaggt tgtggttgaa
2341 aaggtgcaaa atgcaacagt ccaaaccaac aatgaactca caggagcact ccatcacctg
2401 aggtctgcaa ggataagata ttatgtcaaa tgtttccaag aagccattta ctccttactc
2461 caaatcactg gtgcagcctt tgtcacttca cgcatcgtga aacgcatgaa catctcaaat
2521 ctctggtcaa aaccacccgt cgaagagggt gatgagcctg aagacaaagg aggatgccct
2581 aaacccaggg atgaagatga cctcaccatt gactctaaag atataaaagt ggaagggaaa
2641 aagggcaaaa acaagtctgg tcggggcaag aaacacacag ccttctcatc caagggtctc
2701 agtgatgaag agtacgatga gtacaagaga atcagagagg agaggaacgg taaatactca
2761 atagaggaat acctccaaga tagagacaga tactatgaag aacttgccat tgctaaggcc
2821 actgaagagg acttctgtga agaggaggaa atcaaaatcc gccagagaat cttccgaccc
2881 accaggaagc aacggaaaga ggagagggcc acgctcggac tcgtcacagg atcagaaatc
2941 aggaaaagaa acccagatga ctttaaacca aaaggaaaat tgtgggctga tgacaacagg
3001 agtgtggatt acaatgagag aatagatttt gaggcccccc cgagcgtttg gtctagaata
3061 gtcaattttg gcacaggctg gggattctgg gtttctccaa gtctcttcat aacttcaaca
3121 catgtcatac caaaaggaat tactgaagcc tttggagtgc ccatgaacca aatccaaatt
3181 cacaaatccg gagaattttg ccgtttgcgg tttccaaaac caatcagacc agacgtgagt
3241 gggatgatct tggaagaggg tgcccctgaa ggcactgttg tgtctattct catcaaaagg
3301 acaacagggg agctgatgcc tcttgcagtc agaatgggaa cccatgccac aatgaaaatt
3361 caaggtagaa cggtgggtgg tcagatgggt atgcttctca ctggttcaaa tgccaaaagc
3421 atggatttgg gtacaacgcc aggtgattgc gggtgtccat acatctacaa aaggggcaat
3481 gacttcgtgg ccattggggt gcacactgca gcagcacgtg gaggcaacac agtcatatgt
3541 gccacacagg gaagtgaagg tgaggccact cttgaaggag gtgacaacaa gggcacctac
3601 tgtggagcac ccattctggg gcctggcagt gcaccaaaac tgagcacaaa aacaaaattc
3661 tggagatctt ccaatacacc gcttccccca ggcacctatg aaccagcgta ccttggtggg
3721 agagacccgc gtgtgaaggg aggcccgtct ctacagcagg ttatgagaga tcaactcaaa
3781 ccctttacag agcccagggg gaagccacca aacccaaatg ttctggagtc agcaaagaag
3841 actatcatca atgttttgga acaaaccatc gacccccctc aaaagtggtc gtatgcccaa
3901 gcttgcgcat ctcttgacaa aacgacctcc agtggatacc cacaccacgc ccggaagaat
3961 gattattgga atggtgaaac attcacaggg aaactcgcag accaggcttc aaaggcaaat
4021 ctcatgtttg aagaaggcaa gcacatgcaa ccagttttca ctgcagcact caaagacgag
4081 cttgtaaaaa ctgacaaaat ttatggcaag attaagaaaa gactcctgtg gggttctgac
4141 ctctccacca tgattcgttg cgctagagca ttcggtggtc tcatggacga gcttaaagca
4201 aactgcattg cactccctgt cagagttggt atgaatatga atgaagatgg tcccataata
4261 tttgagaaac actccaggta cagataccat tatgatgcag actactcccg ctgggattcc
4321 acacaacagc gggcagtgct ggaagcggca cttgaaatta tggtgagatt ttctgctgaa
4381 ccacagctgg cacaaatagt ggcagaggac ctgctgtcac caagtgtggt ggatgtgggc
4441 gacttcaaaa tcgcgatcaa tgaaggccta ccatctggtg tgccttgcac ctcacaatgg
4501 aactctattg cccactggtt actcaccctg tgtgccctct ctgaagtgac aggactaggc
4561 cccgacatca tacaagccaa ctccatgtac tctttctatg gtgatgatga gattgtgagc
4621 acagacataa aattggaccc agagaaatta actgcaaagc tcaaagaata tggccttaaa
4681 cccacacggc ccgacaaaac tgagggaccg ctggtgatca gtgaggacct gaatgggttg
4741 acattcctac gccggacagt gacccgcgac ccagcaggct ggtttggaaa attggaccaa
4801 agttctatcc tcaggcagat ttattggaca aggggaccca accatgaaga tcccagtgaa
4861 accatgatac cacacgcaca gagacccgtg cagctcatgg cattattagg agaatcctcc
4921 ctacatggac catcatttta cagcaaggtc agcaagctgg tcatatctga actcaaagag
4981 ggaggaatgg atttttatgt gcccagacaa gagtcaatgt tcagatggat gaggttctca
5041 gatctaagca catgggaggg cgatcgcaat ctggctccca gttttgtgaa tgaagatggc
5101 gtcgaatgac gccgctccat ctaatgatgg tgctacgggc ctcgttccag agatcaacac
5161 cgagaccctt cctttggaac cagtggctgg tgcatccctt gcagcagctg tcactggtca
5221 aaacaatata attgatccct ggattagaac aaattttgta caagcaccca atggggaatt
5281 tactgtatca cccagaaatt ccccaggaga gattcttcta aatttggaat taggtcctga
5341 tttaaatcct tatttggcac acctgtctag aatgtacaat ggctacgctg gcggagttga
5401 agtccaggtg ctcttggcgg ggaatgcgtt caccgccgga aagatccttt tcgccgctgt
5461 gccaccaaat tttccagttg aatttcttag tcctgctcaa ataactatgc ttccacattt
5521 gatagttgat gttagaactc ttgaaccaat catgatacct cttcctgatg tgagaaacac
5581 cttcttccac tacaacaacc ggccctctga gcgcatgcgc ttagtggcta tgctgtacac
5641 tcctttaaga tccaatggtt caggtgatga tgttttcaca gtctcgtgta gagttttaac
5701 caggcctacc ccagactttg agttcactta tttagtccca ccttcagttg aatctaaaac
5761 aaaacctttt tctctcccta tcctgactat ctctgagctg accaattcaa gattcccagc
5821 acctattgat tcattgttta ctgctcaaaa taatgtcctt aatgtccagt gtcaaaatgg
5881 ccggtgcact ctggatggag agctgcaagg aaccacccaa ttacttccaa ctggaatatg
5941 tgccttcagg ggaaagataa cagcagatgt agaacatcag catgatgaca ggtggcactt
6001 gagtttaacg aacctcaatg gaaccccttt tgatccaaca gaagatgtcc cagccccact
6061 aggcacccct gacttcacag gcctcctctt tggagttgca agccaaagaa atgtcggtgg
6121 gtcaggcaac aacaccacca gggcacatga ggctgtgata tcaacaacca gcacacaatt
6181 tgttccaaaa ttaggttctg tcaactttgg gagtgagagt gacgattttc aggtttctca
6241 gccaactaag ttcacaccag ttgggatcaa aattgaaact ggacaccctt ttgaacaatg
6301 gagattgccc aactatgctg gagcactaac acttaatatg aaccttgccc cacctatcgc
6361 tcccaacttt ccaggtgagc aattgctatt ctttaggtct aacatccctt gtgctggtgg
6421 tatcagtgac ggtgtcattg actgtctgct tcctcaggag tggatacaac acttctacca
6481 ggagtctgct ccttctcaat cagatgtggc tctaatcagg tacgtcaacc ctgacacggg
6541 tcgcactctc tttgaggcga agctccacag gaccggatac atcactgttg cccacaccgg
6601 tgattaccct cttgttgtcc cctctaatgg cttcttcaga tttgactctt gggtaaacca
6661 gttttactca cttgccccca tgggaactgg gaatgggcgt agaaggattc agtaatggca
6721 ggagctttta tagcaggtct tgcaggtgac atgctcacca atactgttgg ctctctggcg
6781 aatgccggag caaacgccat aaaccaaaag atagactttg agaacaacaa acaattgcaa
6841 gctgcctctt tccaacatga taaagacatg ctccgcgcac aggtgaatgc aaccaaacaa
6901 ctgcagtcag acatgatcgc catcaagcag gggatattga ccgcgggcgg cttttcccct
6961 actgatgcag cgaggggggc cgtgggggca cccatgacaa aggttctcga ttggtctggc
7021 acccgctatt gggcaccaaa ttctaccaag acaacaagct attcagggca attcacatca
7081 acacctgtgc atacaccaaa tttgagtagc aagcccaaga ccacaagtgt caagtcccca
7141 tctccttctt cttcctctgg tagtgtttat agcttagcaa ctcagtcaac ttcactgtcc
7201 ggaccttctt caggttcctc tgcttcttct gcttcaacac aatcaacaaa attaagctca
7261 acttcttcta tgagtagaac aattgattgg gtcaatcaac aaagaagtct tagcccatac
7321 atgagtggag ctcttaacat ctcccatgtg acacctccat caagtagagc atctagttcg
7381 ggaacagtct caactgtccc caaagaagtt ttggactcct ggacatctgc atttaacaca
7441 cacagacagc cgctcttcgc acaccttagg gtaagggggg agtcacgtgt ttagtgaaaa
7501 gaattaatta gatttaatca ggcttaaatt taatttgatc tttta
//