Typing tool
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Typing tool
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Complete norovirus genomes
| PQ304611 | GII.17 | |
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| GII.P17 |
ORF1: 5..5113
ORF2: 5094..6710
ORF3: 6710..7489
LOCUS PQ304611 7560 bp RNA linear VRL 17-OCT-2024
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/Clinton0099/2023/USA, complete
genome.
ACCESSION PQ304611
VERSION PQ304611.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7560)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7560)
AUTHORS Mosher,L., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2024) Viral Gastroenteritis Branch, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. v. 11.1.2; SPAdes v. v. 3.6
Sequencing Technology :: Sanger dideoxy sequencing; Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7560
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/Clinton0099/2023/USA"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="08-Jul-2023"
/note="genotype: GII.17[P17]"
gene 5..5113
/gene="ORF1"
CDS 5..5113
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XGK29406.1"
/translation="MKMASNDASAAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGAR
SKQPPPGETKQTPRPPRPPTPELVKKIPPPPPNGEDEPKVVYKVGEGVSGLPDLTTVA
QPDAQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPA
AISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLSGETFPYTAFDNNCYAFCCWVLEL
NDSWLSRRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDV
IGKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLIMKW
FFPKKEETNELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARK
LSSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLA
RELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIVITTNLANPAPLDYVNFEACSRRIDFLVYADAPD
IEKAKRDFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLI
ARASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSV
KTLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNTTVQTNNELAGALH
HLRSARIRYYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDK
GGCPKPRDEDGLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATL
GLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFW
VSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGA
PEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAP
ILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPF
TEPRGRPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGHPHHVRKN
DYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWG
SDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTA
KLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRAVTRDPAGWFGKLDQNSILRQLYWT
RGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVP
RQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 5..1003
/gene="ORF1"
/product="p48"
mat_peptide 1004..2101
/gene="ORF1"
/product="NTPase"
mat_peptide 2102..2638
/gene="ORF1"
/product="p22"
mat_peptide 2639..3037
/gene="ORF1"
/product="VPg"
mat_peptide 3038..3580
/gene="ORF1"
/product="Pro"
mat_peptide 3581..5110
/gene="ORF1"
/product="RdRp"
gene 5094..6710
/gene="ORF2"
CDS 5094..6710
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGK29407.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGEDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLLFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6710..7489
/gene="ORF3"
CDS 6710..7489
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGK29408.1"
/translation="MAGTFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGILAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSIPSAPQSKPAKPRSLGSSSSSSSVYSMSTQST
SLISGSSNNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgtt gctggcaaaa acaacaacaa
61 cgacaaggaa aaatcttcaa gtgacagctt gttttctaac atgactgtta cttttaagaa
121 agccctcggg gcgcggtcta agcagccgcc cccgggagaa acgaaacaaa caccaagacc
181 accaaggcca ccgacaccgg aattggtgaa gaagatacct ccaccccccc ctaatggcga
241 ggatgaacca aaggtagtgt ataaggtggg agaaggtgtg tctgggctgc ccgacttaac
301 gaccgtggca caacctgacg cacagaacac agcctatagt gttcccccac ttagccagag
361 agaggtcggc gaagctaaag aaccgttgcc tggctccatt ctggaaatgt gggatggtga
421 gatctaccat tatgggctgt atgttgagcg ggggcatgta ctgggagtgc acaaaccacc
481 tgccgcaata agccttgcca aaattgaatt aacaccgctg tctctctact ggagagtggt
541 ttacactccc cagtacttga tagctccaga gacccttaag aatttaagtg gagagacttt
601 cccatacacg gcctttgaca acaactgtta tgccttctgt tgttgggttt tggagctcaa
661 cgactcctgg cttagcagaa gaatgatcca aagaacaacc ggattcttca gaccgtatca
721 ggactggaac agaaaaccct tgccaaccat ggatgaacca aaaatcaaaa aggccgcgaa
781 tgctgttctg tgtgctctct cctcactctt cactaggccc atcaaagatg tcattggaaa
841 gcttaaacca ctgaacatta tgaacatact ggcaacttgt gattggactt ttgcgggcat
901 agtggaatcc atgatccttc ttgctgagct ctttggggtg ttctggacgc ccccagatgt
961 gtctgcaata attgctccct tactcggtga ctacgagatg caaggccccg aagacctggc
1021 cgtggaactt gtgcccgtgg taatgggagg aataggtttg gtgttaggat tcaccaagga
1081 aaagatcggc aagatgcttt catcagctgc gaccacactc agggcctgta aggatctagg
1141 gtcttatggg ttggaaatac tcaaactgat catgaagtgg ttcttcccca agaaggagga
1201 gaccaacgag ctagccatgg tgagggccat tgaggatgca gttctggatt tggaggcaat
1261 agaaaacaac cacatgacca ctctccttaa ggacaaagac agcctggcca catacatgag
1321 aactcttgac ttggaagaag aaaaagcaag gaaactgtca tccaaatcgg cgtcacctga
1381 catcgtgggc acagtaaacg cattattggc aaggatagca gccgccaggt cgctggtcca
1441 caaggctaag gaggagctct cgagcagaca gaggcctgtt gttgtgatga tatcaggtag
1501 gccaggtata ggaaagaccc atctggccag agagttagcc aagaaggttg cgtcaacact
1561 gtcaggcgac caaaggattg gactgatacc tagaaatggc gtcgaccatt gggacgccta
1621 caaaggagag cgggtggttc tgtgggatga ctatggcatg agtaacccta tacaggacgc
1681 tctgaggctc caagaattgg ctgacacctg tcctctgacc ctaaattgtg acaggattga
1741 gaacaaagga aaagtgttcg acagtgacgc catagtcata acaaccaacc ttgcaaaccc
1801 agcaccactg gattatgtca actttgaggc ttgttccaga cgcatagact tcttggtgta
1861 tgcagacgcg cctgacatcg agaaggctaa gcgtgacttc cctggccaac cagatatgtg
1921 gaaagaccat tacagatcag acttctcaca cattaaacta cagctggcac cacagggagg
1981 ctttgataag aatggcaaca ccccacatgg caaaggtgtg gttaagtctc tgacgattgg
2041 ttctctgatc gccagggctt ctggcttgct ccatgagaga atggacgaat tcgagctcca
2101 aggttctgac ttaccaacct tcaatttcga ccgtaacaaa gtcgccgcct tcagacaatt
2161 ggcagctgaa aacaaatatg gtcttatgga cacactgagg gtcggcaacc aactgaaaag
2221 tgtcaaaacc ctggatgagc tgaagcaggc tataaagaac attaccatca agaagtgcca
2281 gatagtgtac aatggatgca cctacaccat ggaatctgat gggaggaaca aggttgtggt
2341 tgaaaaggtt caaaatacaa cagtccaaac caataatgaa cttgcaggag cactccacca
2401 cctgagatct gcaaggataa ggtattatgt caaatgtttc caagaagcta tttactctct
2461 actccaaatt gctggtgcgg ccttcgtcac cacacgcatc gtgaggcgca tgaacatctc
2521 aaacctctgg tcgaagccac ccgtcgaaga gggtgatgag cctgaagaca aaggggggtg
2581 ccccaagccc agggatgaag atggcctcac tatcgactcc aaagacatta aagcagaagg
2641 gaagaagggc aagaacaaat ctggccgggg caagaaacac acagctttct catccaaggg
2701 cctcagtgat gaagagtacg atgagtacaa gagaatcagg gaggagagga atggcaaata
2761 ctcaatagag gaatacctcc aggataggga tagatactat gaagaacttg ccattgctaa
2821 ggccactgag gaagacttct gtgaagagga ggaaatcaaa attcgccaga gaatcttccg
2881 gcccaccagg aagcaacgga gagaggaaag agccacgctt gggcttgtca caggatcgga
2941 gatcagaaag aggaatccag atgactttaa gccaaaagga aagttgtggg ctgatgacaa
3001 cagaagtgtg gactacaatg agaggataga ttttgaggct cccccgagtg tttggtctag
3061 gatagtcaac tttggtacag gatggggatt ctgggtctcc ccgagtctct ttataacttc
3121 aacacatgtc ataccaaaag gaatcactga ggcttttgga gtccccatta accaaattca
3181 aattcacaaa tctggagagt tttgccgctt gcggtttcca aaaccaatca ggccagacgt
3241 gagtggaatg atcttagaag agggtgcccc tgaaggcact gttgtgtcca ttctcatcaa
3301 gaggacaaca ggggaactga tgcctctcgc agttagaatg ggaactcatg ccacaatgaa
3361 aatccaaggt agaacggtgg gcggtcaaat gggcatgctt ctcactggct caaacgctaa
3421 aagcatggac ctaggcacaa caccaggtga ctgtgggtgc ccatacatat acaaaagggg
3481 caatgacttc gtggtcattg gggtgcacac tgcagcagcc cgtggaggca acacggtcat
3541 atgtgccaca cagggaagtg aaggcgaagc caccctcgaa ggaggtgaca acaagggcac
3601 ctattgtggg gcccccatct tgggacctgg caacgcacca aaattgagca caaaaacaaa
3661 attctggaga tcttctaacg cgccgcttcc tccaggcacc tatgaaccag cataccttgg
3721 tggaaaagac ccgcgtgtga agggaggccc atctctacaa caggttatga gagaccaact
3781 caaacctttt acagagccca gagggaggcc accaaaacca agtgttctag aatcagcaaa
3841 gaagaccatc atcaatgttc tagaacaaac cattgacccc cctgaaaagt ggtcatatgc
3901 ccaagcttgt gcatccctcg acaagacaac ctccagtgga cacccgcatc acgtccggaa
3961 gaatgattat tggagtggcg aatccttcac ggggaaactt gcagaccagg cctcaaaagc
4021 aaaccttatg tatgaggaag gcaagcacat gcaaccagtt tacaccgcag cactcaaaga
4081 cgagctcgtg aaaactgata aaatttacgg caagatcaag aaaagactcc tgtggggctc
4141 tgacctatcc accatgattc gatgcgccag ggcatttggt ggcctcatgg atgagctcaa
4201 agctaattgt atcacactcc ctatcagagt tggtatgaac atgaatgagg atggtcccat
4261 aatatttgaa aagcactcca ggtacaggta ccactatgat gctgattact cccgctggga
4321 ttccacacaa cagcgggcag tgctggaagc ggcacttgaa attatggtga gattttctgc
4381 tgagccacag ttggcacaaa tagtggcaga ggacctgcta tcaccaagtg tggttgatgt
4441 gggcgatttc aaaattgcta tcaatgaagg cctaccatct ggcgtaccct gcacttcaca
4501 atggaattct attgcccact ggttactcac cctgtgtgcc ctgtctgaag taacaggact
4561 aggccctgac atcatacaag ccaactccat gtactctttc tatggtgatg atgagatagt
4621 gagcacagac ataaaattag acccagagaa attgactgca aaactcaaag aatatggcct
4681 taaacccacc cggcctgaca agactgaggg gccactggta attagtgagg acctgaatgg
4741 gttgactttc ctccgccgag cagtcacccg cgatccagcg ggttggtttg gaaagttgga
4801 ccaaaactcc atcctcaggc agctgtactg gacaagggga cccaaccatg aagaccccag
4861 tgagaccatg ataccacacg cacagagacc tgtgcagctc atggcactgc taggagagtc
4921 ctccctacat ggaccctcat tttacagcaa ggttagcaag ctggtcatat ctgaacttaa
4981 agagggggga atggattttt atgtgcccag acaagagtca atgttcagat ggatgaggtt
5041 ctcagatcta agcacatggg agggcgatcg caatctggct cccagttttg tgaatgaaga
5101 tggcgtcgaa tgacgccgct ccatctaatg atggtgctgc tggtctcgta ccagagggca
5161 ataacgagac ccttccccta gaaccagttg cgggcgcagc tatagccgca cccgtcactg
5221 gccaaaacaa tataattgac ccctggatta gaacaaattt tgtgcaagca ccaaatggag
5281 agttcacagt gtcacccaga aactctcctg gagaaatttt actaaaccta gagttgggcc
5341 ctgatttgaa cccttatttg gctcatttgt caaggatgta caatgggtat gctggtggag
5401 ttgaagtcca ggttctcctg gcggggaacg cgttcactgc cgggaagatc ctcttcgccg
5461 ctgtcccgcc aaattttcca gtggaattct taagcccagc ccagattaca atgctcccac
5521 atataatagt agatgttagg actcttgaac caataatgat cccattacct gatgttagga
5581 acacattctt ccactataat aaccagccca acagccgcat gagattagtg gctatgctct
5641 atacccccct tagatctaat ggctcaggtg aggatgtttt cactgtttct tgcagggttt
5701 tgactaggcc cactcctgat tttgagttca cttatctagt gccaccctct gttgaatcta
5761 agactaagcc cttttcctta cccattctaa ccctttctga gctcacaaat tcgaggttcc
5821 cggtccccat tgattcgctc ttcaccgccc agaacaatgt gttgcaggtg cagtgtcaaa
5881 atggcaggtg cacacttgac ggtgagctac aaggcacaac ccagttgctc ccatctggca
5941 tctgcgcgtt cagaggacgg gtgacagcag aaactgacaa tcctgacaag tggcacatgc
6001 aactgcaaaa cctcaatggc acaacatatg acccaactga tgatgtgcca gccccactgg
6061 gtacacctga cttcaagggc gtcgtgtttg ggatggcaag ccaaaggaat gtgggtaacg
6121 atgcgcccgg ctcaaccagg tcccatgagg cggtaatttc aacctacagc cccagatttg
6181 ttccaaaatt aggctctgtc aattttaaaa gtaatgatga tgatttccaa ttgcagccaa
6241 caagattcac accagtgggc attaatgatg atggcaacca cccgttcaga caatgggaat
6301 tgccagacta ttcaggggtg cttaccttga acatgaacct tgcccccccg gtagctccaa
6361 atttccctgg tgaacaatta ttgctcttca gatcttctgt gccatgttca ggaggttaca
6421 accaaggtat tatagattgt cttatccccc aagaatggat ccaacacttc taccaggaat
6481 cagcaccttc tcagtcagaa gtggccctga tcaggtacgt caaccccgac acgggtcgca
6541 cactgtttga ggcaaaattg catagatctg gctatatcac tgtggctcac tctggagact
6601 atcctcttgt tgttccggct aatggatact ttagatttga ctcttgggta aatcagtttt
6661 actcactcgc cccaatggga actgggaatg ggcgaaggag ggctcagtaa tggctggaac
6721 tttcattgca ggattggcgg gtgacatgct cacgtcatcc gtgggctccc tggtgaacgc
6781 aggggcaaac gccatcaacc aaaagataga ctttgaaaac aacaaacaac tccagtctgc
6841 ttcctttcaa catgacaaag agatgctcca agcgcaggtg aatgcaacca agcagctgca
6901 atctgagatg atagccctaa aacaggggat tttggccgca ggcggctttt cccccactga
6961 tgcagcgagg ggggccatcg gtgcacccat gacaaaggtg cttgactggt ctggcactcg
7021 atattgggct cccaattcca caaagacaac tggttattcg gggcaattca cctcttcacc
7081 tgtgcacatg tccatcccga gtgctccaca atcaaaaccc gcaaagccca ggtctctagg
7141 ttcctcttct tcttctagta gtgtttatag tatgtctacc caatcaactt ctctaatatc
7201 tggctcttct aataatgctt cttctgcttc tacaaaattg acaaatttaa gctccggctc
7261 ctctcaaaac agaacagcag agtgggtgaa ccaacagaga agtctcagcc ctttcatgag
7321 tggcgcactc aatatatcac atgtcacgcc accttcaagt agggcctcca gttctgggac
7381 ggtctcaacc gtgcccaagg aggttttgga ctcctggaca tctgcattta acacacgcag
7441 acagccgctc ttcgcacacc tcagagtgag gggggagtca cgtgtttagt gaaaagaaat
7501 aattggctat aatatgattt ctttaaaatt tgaatttggc taatttgtat cttttaaaaa
//