Typing tool
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Typing tool
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Complete norovirus genomes
| PQ304610 | GII.17 | |
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| GII.P17 |
ORF1: 5..5113
ORF2: 5094..6710
ORF3: 6710..7489
LOCUS PQ304610 7560 bp RNA linear VRL 17-OCT-2024
DEFINITION Norovirus GII isolate Hu/GII.17[P17]/Michigan0047/2023/USA,
complete genome.
ACCESSION PQ304610
VERSION PQ304610.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7560)
AUTHORS Chhabra,P., Wong,S., Niendorf,S., Lederer,I., Vennema,H., Faber,M.,
Nisavanh,A., Jacobsen,S., Williams,R., Colgan,A., Yandle,Z.,
Garvey,P., Al-Hello,H., Ambert-Balay,K., Barclay,L., de Graaf,M.,
Celma,C., Breuer,J., Vinje,J. and Douglas,A.
TITLE Increased circulation of GII.17 noroviruses, six European countries
and the United States, 2023 to 2024
JOURNAL Euro Surveill 29 (39) (2024)
REMARK DOI: 10.2807/1560-7917.ES.2024.29.39.2400625
REFERENCE 2 (bases 1 to 7560)
AUTHORS Mosher,L., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (10-SEP-2024) Viral Gastroenteritis Branch, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. v. 11.1.2; SPAdes v. v. 3.6
Sequencing Technology :: Sanger dideoxy sequencing; Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7560
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17[P17]/Michigan0047/2023/USA"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="22-Feb-2023"
/note="genotype: GII.17[P17]"
gene 5..5113
/gene="ORF1"
CDS 5..5113
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XGK29403.1"
/translation="MKMASNDASAAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGAR
SKQPPPGETKQTPRPPRPPTPELVKKIPPPPPNGEDEPKVVYKVGEGVSGLPDLTTVA
QPDAQNTAYSVPPLNQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPA
AISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLSGETFPYTAFDNNCYAFCCWVLDL
NDSWLSRRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDV
IGKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLIMKW
FFPKKEEASELAMVRAIEDAILDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARK
LSSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLA
RELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPD
IEKAKRDFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLI
ARASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSV
KTLDELKQAIKNITIKKCQIVYNGRTYTMESDGRNKVVVEKVQNATVQTNNELAGALH
HLRSARIRYYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDK
GGCPKPRDEDGLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATL
GLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFW
VSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGA
PEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAP
ILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKN
DYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWG
SDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTA
KLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWT
RGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVP
RQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 5..1003
/gene="ORF1"
/product="p48"
mat_peptide 1004..2101
/gene="ORF1"
/product="NTPase"
mat_peptide 2102..2638
/gene="ORF1"
/product="p22"
mat_peptide 2639..3037
/gene="ORF1"
/product="VPg"
mat_peptide 3038..3580
/gene="ORF1"
/product="Pro"
mat_peptide 3581..5110
/gene="ORF1"
/product="RdRp"
gene 5094..6710
/gene="ORF2"
CDS 5094..6710
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XGK29404.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCALDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGDHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6710..7489
/gene="ORF3"
CDS 6710..7489
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XGK29405.1"
/translation="MAGTFIAGLVGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGILAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPIPSAPQSKPAKPRSLGSSSSSSSVYSMSTQLT
SLISGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgtt gctggcaaaa acaacaacaa
61 cgacaaggaa aaatcttcaa gtgacagctt gttttctaac atgactgtta cttttaagaa
121 agccctcggg gcgcggtcta agcagccgcc cccgggagaa acgaaacaaa caccaagacc
181 accaaggcca ccgacaccgg aattggtgaa gaagatacct ccaccccccc ctaatggcga
241 ggatgaacca aaggtagtgt ataaggtggg agaaggtgtg tctgggctgc ccgacttaac
301 aaccgtggca caacctgacg cacagaacac agcctatagt gtccccccac ttaaccagag
361 agaggtcggc gaagctaaag aaccgttgcc tggctccatt ctggaaatgt gggatggtga
421 gatctaccat tatgggctgt atgttgagcg ggggcatgta ctgggagtgc acaaaccacc
481 tgccgcaata agccttgcca aaattgaatt aacaccgctg tctctctact ggagagtggt
541 ctacactccc cagtacttga tagctccaga gacccttaag aatttaagtg gagagacttt
601 cccatacacg gcctttgaca acaactgtta tgccttctgt tgttgggttt tggatctcaa
661 cgactcctgg cttagcagaa gaatgatcca aagaacaacc ggattcttca gaccgtatca
721 ggactggaac agaaaaccct tgccaaccat ggatgaacca aaaatcaaaa aggccgcgaa
781 tgctgttctg tgtgctctct cctcactctt cactaggccc atcaaagatg tcattggaaa
841 gcttaaacca ctgaacatta tgaacatact ggcaacttgt gactggactt ttgcgggcat
901 agtggaatcc atgatccttc ttgctgagct ctttggggtg ttctggacgc ccccagatgt
961 gtctgcaata attgctccct tactcggtga ctacgagatg caaggccccg aagacctggc
1021 cgtggaactt gtgcccgtgg taatgggagg aataggtttg gtgttaggat tcaccaagga
1081 aaagatcggc aagatgcttt catcagctgc gaccacactc agggcctgta aggatctagg
1141 gtcttatggg ttggagatac tcaaactgat catgaagtgg ttcttcccca agaaggagga
1201 ggccagcgag ctagccatgg tgagggccat tgaggatgca attctggatt tggaggcaat
1261 agaaaacaac cacatgacca ctctccttaa ggacaaagac agcctggcca catacatgag
1321 aactcttgac ttggaagaag aaaaagcaag gaaactgtca tccaaatcgg cgtcacctga
1381 catcgtgggc acagtaaacg cattattggc aaggatagca gccgccaggt cgctggtcca
1441 caaggctaag gaggagctct cgagcagaca gaggcctgtt gttgtgatga tatcaggtag
1501 gccaggtata ggaaagaccc atctggccag agagctagcc aagaaggtcg cgtcaacact
1561 gtcaggcgac caaaggattg gactgatacc tagaaatggc gtcgaccatt gggacgccta
1621 caaaggagag cgggtggttc tgtgggatga ctatggcatg agtaacccta tacaggacgc
1681 tctgaggctc caagaattgg ctgacacctg tcctctgacc ctaaattgtg acaggattga
1741 aaacaaagga aaagtgttcg acagtgacgc cataatcata acaaccaacc ttgcaaaccc
1801 agcaccactg gattatgtca actttgaggc ttgttccaga cgcatagact tcttggtgta
1861 tgcagacgcg cctgacatcg agaaggctaa gcgtgacttc cctggccaac cagatatgtg
1921 gaaagaccat tacagatcag acttctcaca cattaaactt cagctggcac cacagggagg
1981 ctttgataag aatggcaaca ccccacatgg caaaggtgtg gttaagtctc tgacgattgg
2041 ttctctgatc gccagggctt ctggcttgct ccatgagaga atggacgaat tcgagctcca
2101 aggttctgac ttaccaacct tcaatttcga ccgtaacaaa gtcgccgcct tcagacaatt
2161 ggcagctgaa aacaaatatg gtcttatgga cacactgagg gtcggcaacc aactgaaaag
2221 tgtcaaaacc ctggatgaac tgaagcaggc tataaagaac atcaccatca agaagtgcca
2281 gatagtgtac aatggacgca cctacaccat ggaatctgat gggaggaaca aggttgtggt
2341 tgaaaaggtt caaaatgcaa cagtccaaac caataatgaa cttgcaggag cactccacca
2401 cctgagatct gcaaggataa ggtattatgt caaatgtttc caagaagcta tttactctct
2461 actccaaatt gctggtgcgg ccttcgtcac cacacgcatc gtgaggcgca tgaacatctc
2521 aaacctttgg tcgaagccac ccgtcgaaga gggtgatgag cctgaagaca aaggggggtg
2581 ccccaagccc agggatgaag atggcctcac tattgactcc aaagacatta aagcagaagg
2641 gaagaagggc aagaataaat ctggccgggg caagaaacac acagctttct catccaaggg
2701 tctcagtgat gaagagtacg atgagtacaa gagaatcagg gaggagagga atggcaaata
2761 ctcaatagag gaatacctcc aggataggga tagatactat gaagaacttg ccattgctaa
2821 ggccactgag gaagacttct gtgaagagga ggaaatcaaa attcgccaga gaatcttccg
2881 gcccaccagg aagcaacgga gagaggaaag agccacgctt gggcttgtca caggatcgga
2941 aatcagaaag aggaatccag atgactttaa gccaaaagga aagttgtggg ctgatgacaa
3001 cagaagtgtg gactacaatg agaggataga ttttgaggct cccccgagtg tttggtctag
3061 gatagtcaac tttggtacag gatggggatt ctgggtctcc ccgagtctct ttataacttc
3121 aacacatgtc ataccaaaag gaatcactga ggcttttgga gtccccatta accaaattca
3181 aattcacaaa tctggagagt tttgccgctt gcggtttcca aaaccaatca ggccagacgt
3241 gagtggaatg atcttggaag agggtgcccc tgaaggcact gttgtgtcca ttctcatcaa
3301 gaggacaaca ggggaactga tgcctctcgc agttagaatg ggaactcatg ccacaatgaa
3361 aatccaaggt agaacggtgg gcggtcaaat gggcatgctt ctcactggct caaacgctaa
3421 aagcatggac ctaggcacaa caccaggtga ctgtgggtgc ccatacatat acaaaagggg
3481 caatgacttc gtggtcattg gggtgcacac tgcagcagcc cgtggaggca acacggtcat
3541 atgtgccaca cagggaagtg aaggcgaggc caccctcgaa ggaggtgaca acaaaggcac
3601 ctattgtgga gcccccatct tgggacctgg caacgcacca aaattgagca caaaaacaaa
3661 attctggaga tcttctaacg cgccgcttcc tccaggcacc tatgaaccag cataccttgg
3721 tggaaaagac ccgcgtgtga agggaggccc atctctacaa caggttatga gggaccaact
3781 caaacctttt acagagccca gagggaagcc accaaaacca agtgtcctag aatcagcaaa
3841 gaagaccatc atcaatgttc tagaacaaac cattgacccc cctgaaaagt ggtcatatgc
3901 ccaagcttgt gcatccctcg acaagacaac ctccagtgga tacccgcatc acgtccggaa
3961 gaatgattat tggagtggcg aatccttcac ggggaaactt gcagaccagg cctcaaaagc
4021 aaaccttatg tatgaggaag gcaagcacat gcaaccagtt tacaccgcag cactcaaaga
4081 cgagctcgtg aaaactgata aaatttatgg caagatcaag aaaagactcc tgtggggctc
4141 tgacctatcc accatgattc gatgcgccag ggcatttggt ggcctcatgg atgagctcaa
4201 agctaattgt atcacactcc ccatcagagt tggtatgaac atgaatgagg atggtcccat
4261 aatatttgaa aagcactcca ggtacaggta ccactatgat gctgattact cccgctggga
4321 ttccacacaa cagcgggcag tgctggaagc ggcacttgaa atcatggtga gattttctgc
4381 tgagccacag ttggcacaaa tagtggcaga ggacctgcta tcaccaagtg tggttgatgt
4441 gggcgatttc aaaattgcta tcaatgaagg cctaccatct ggcgtgccct gcacttcaca
4501 atggaattct attgcccact ggttactcac cctgtgtgcc ctgtctgaag taacaggact
4561 aggccctgac atcatacaag ccaactccat gtactctttc tatggtgatg atgagatagt
4621 gagcacagac ataaaattag acccagagaa attaactgca aaactcaaag aatatggcct
4681 taaacccacc cggcctgaca agactgaggg gccactggta attagtgagg acctgaatgg
4741 gttgactttc ctccgccgaa cagtcacccg cgatccagcg ggttggtttg gaaagttgga
4801 ccaaaactcc atcctcaggc agctgtactg gacaagggga cccaaccatg aagaccccag
4861 tgagaccatg ataccacacg cacagagacc tgtgcagctc atggcactgc taggagagtc
4921 ctccctacat ggaccctcat tttatagcaa ggttagtaag ctggtcatat ctgaacttaa
4981 agagggagga atggattttt atgtgcccag acaagagtca atgttcagat ggatgaggtt
5041 ctcagatcta agcacatggg agggcgatcg caatctggct cccagttttg tgaatgaaga
5101 tggcgtcgaa tgacgccgct ccatctaatg atggtgctgc tggtctcgta ccagagggca
5161 ataatgagac ccttccccta gaaccagttg cgggcgcagc tatagccgca cccgtcactg
5221 gccaaaacaa tataattgac ccctggatta gaacaaattt tgtgcaagca ccaaatggag
5281 agttcacagt gtcacccaga aactctcctg gagaaatttt actaaaccta gagttgggcc
5341 ctgatttgaa cccttatttg gctcatttgt caaggatgta caatgggtat gctggtggag
5401 ttgaagtcca ggttctcctg gcggggaacg cgttcactgc cgggaagatc ctcttcgccg
5461 ctgtcccgcc aaatttccca gtggaattct taagcccagc ccagatcaca atgctcccac
5521 atataatagt agatgttagg actcttgaac caataatgat cccattacct gatgttagga
5581 acacattctt ccactataat aaccagccca acagccgcat gagattagtg gctatgctct
5641 atacccccct tagatctaat ggctcaggtg atgatgtttt cactgtttct tgcagggttt
5701 tgactaggcc cactcctgat tttgagttca cttatctagt gccaccctct gttgaatcta
5761 agactaagcc cttttcctta cccattctaa ccctttctga gctcacaaat tcgaggttcc
5821 cggtccccat tgattcgctt ttcaccgccc agaacaatgt gttgcaggtg cagtgtcaaa
5881 atggcaggtg cgcacttgac ggtgagctac aaggcacaac ccagttgctc ccatctggca
5941 tctgtgcgtt cagaggacgg gtgacagcag aaactgacaa tcctgacaag tggcacatgc
6001 aactgcaaaa cctcaatggc acaacatatg acccaactga tgatgtgcca gccccactgg
6061 gtacacctga cttcaagggc gtcgtgtttg ggatggcaag ccaaaggaat gtgggtaacg
6121 atgcgcccgg ctcaaccagg tcccatgagg cggtaatttc aacctacagc cccagatttg
6181 ttccaaaatt aggctctgtc aatttcaaaa gtaatgacga tgatttccaa ttgcagccaa
6241 caaggttcac accagtgggc attaatgatg atggcgacca cccgttcaga caatgggaat
6301 tgccagacta ttcaggggtg cttaccttga acatgaacct tgcccccccg gttgctccaa
6361 atttccctgg tgaacaatta ttattcttca gatcttctgt gccatgttca ggaggttaca
6421 accaaggtat tatagattgt cttatccccc aagaatggat ccaacacttc taccaggaat
6481 cagcaccttc tcagtcagac gtggccctga tcaggtacgt caaccccgac acgggtcgca
6541 cactgtttga ggcaaaattg catagatctg gctatatcac tgtggctcac tctggagact
6601 atcctcttgt tgttccggct aatggatact ttagatttga ctcttgggta aatcagtttt
6661 actcactcgc cccaatggga actgggaatg ggcgaaggag ggctcagtaa tggctggaac
6721 tttcattgca ggactggtgg gtgacatgct cacgtcatcc gtgggctccc tggtgaacgc
6781 aggggcaaac gccatcaacc aaaagataga ctttgaaaac aacaaacaac tccagtctgc
6841 ttcctttcaa catgacaaag agatgctcca agcgcaggtg aatgcaacca agcagctgca
6901 atctgagatg atagccctaa aacaggggat tttggccgca ggcggttttt cccccactga
6961 tgcagcgagg ggggccatcg gtgcacccat gacaaaggtg cttgactggt ctggcactcg
7021 atattgggct cccaattcca caaagacaac tggttattcg gggcaattca cctcttcacc
7081 tgtgcacatg cccatcccga gtgctccaca atcaaaaccc gcaaagccca ggtctctagg
7141 ttcctcttct tcttctagta gtgtttatag tatgtctacc caattaactt ctctaatatc
7201 tggctcttct agtaatgctt cttctgcttc tacaaaattg acaaatttaa gctccggctc
7261 ctctcaaaac agaacagcag agtgggtgaa ccaacagaga agtctcagcc ctttcatgag
7321 tggcgcactc aatatatcac atgtcacgcc accttcaagt agggcctcca gttctgggac
7381 ggtctcaacc gtgcccaagg aggttttgga ctcctggaca tctgcattta acacacgcag
7441 acagccgctc ttcgcacacc tcagagtgag gggggagtca cgtgtttagt gaaaagaaac
7501 aattggctat aatatgattt ctttaaaatt taaatttggc taatttgtat cttttaaaaa
//