Typing tool
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Typing tool
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Complete norovirus genomes
| PQ214837 | GII.4 Apeldoorn | |
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| GII.P4 New Orleans |
ORF1: 5..5104
ORF2: 5085..6707
ORF3: 6707..7513
LOCUS PQ214837 7528 bp RNA linear VRL 01-JAN-2025
DEFINITION Norovirus GII isolate Hu/GII.4 Allegany[P31]/Minnesota0292/2019/USA
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION PQ214837
VERSION PQ214837.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7528)
AUTHORS Barclay,L., Montmayeur,A.M., Cannon,J.L., Mallory,M.L., Reyes,Y.I.,
Lindesmith,L., Wall,H., Baric,R.S., Vinje,J. and Chhabra,P.
TITLE Norovirus GII.4 evolution in the United States since emergence of
GII.4 Sydney
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7528)
AUTHORS Cebelinski,E., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (21-AUG-2024) Viral Gastroenteritis Branch, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. v. 11.1.2; SPAdes v. v. 3.6
Sequencing Technology :: Sanger dideoxy sequencing; Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7528
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.4 Allegany[P31]/Minnesota0292/2019/USA"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="21-Oct-2019"
/note="genotype: GII.4 Allegany[P31]"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XEQ90827.1"
/translation="MKMASNDASAAAVANSNNDIAKSSSDGVLSSMADTFKRALGARP
KQPPPREKPPRPPRPPTPELIRSIPPPPPNGEDEIVVSYSVKDGVSGLPDLSTVRQPE
ESNTAFSVPPLNQRENKDAKEPLTGAILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELAPLSLYWRPVYTPQYLISPDALKKLAGETFPYTAFDNNCYSFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTTDDSKIKKVANIFLCALSSLFTRPIKDIIGK
IRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPAD
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLCMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVRTM
PELKQALKNVSIKKCQIVYGGCTYMLESDGKGNVKIDRIQSTAVQINNELAGALHHLR
SARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNILSLWSKPQVEDTEDATSKDGC
PKPKDDEEFVISSDDIKAEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRNVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFYGVPIKQIQIHKSGEFCRLRFPRPIRTDVTGMILEEGAPEG
TVATLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPTLSTKTKFWRSSTVPLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPGKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMYEEGKNMTPVYTAALKDELVKTDKIYGNIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFEKHSRYKLHYDADYSRWD
STQQRAVLAAALEIMVKFSPEPHLAQVVAEDLLAPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLR
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVSRDAAGWFGKLEQSSILRQMYWTRGP
NHGDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 5..994
/gene="ORF1"
/product="p48"
mat_peptide 995..2092
/gene="ORF1"
/product="NTPase"
mat_peptide 2093..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6707
/gene="ORF2"
CDS 5085..6707
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XEQ90828.1"
/translation="MKMASNDANPSDGSSASLVPEVNNEVMALEPVAGAAIAAPVAGQ
QNIIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLSRMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPNIIIDVRQLEPVLIPLPD
IRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGEDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPVPLERLVTGPSNNLVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGSVTHIAGSRNYTMNLASQNWNRYDPTEEIPAPLGTPDFVGKIQGVL
TQTTKGEGSTRAHTATVLTGSADFSPKLGRIQFATDTENDLEPNQNTRFTPVGVVQNG
GTAHRNEPQQWNLPTYSGRDTHNVHLAPAVAPTFPGEQLLFFRSTIPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYLTVAHSGQHDLV
IPPNGYFRFDSWVNNFYTLAPMGNGTGRRRAV"
gene 6707..7513
/gene="ORF3"
CDS 6707..7513
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XEQ90829.1"
/translation="MAGAFFSGLASDVLGSGLGSLINAGAGAINQKVEFENNKKLQQA
SFQFSSNLQQASFQHDKDMLQAQIEATKKLQQEVMRAKQSMLLEGGFSETDAARGAIN
APMTKVLDWSGTRYWAPDARATTYNAGRFSTPQPSGALSGRTNLRATVPTRGSPSLSS
NSSTATSMHSNQTTSTRLGSTAGSGTSVSSLPSAARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKGVLDSWTGAFNTRRQPLFAHIRQRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgct gttgctaaca gcaacaacga
61 cattgcaaaa tcttcaagtg acggagtgct ttctagcatg gccgacactt ttaaacgagc
121 cctcggggcg cggcctaaac agcctccccc gagggaaaaa ccaccaagac ccccacgacc
181 gcccactcca gaactgatta gaagtatccc ccctccccca cccaacggag aggatgaaat
241 agtggtttct tatagtgtca aagatggtgt ttctggcttg cctgaccttt ccaccgtcag
301 acaaccagaa gaatctaaca cggccttcag tgtccctcca ctcaatcaaa gggagaataa
361 agatgccaag gagccactta ctggggcaat tctggagatg tgggatgggg aaatctacca
421 ttatggcctg tatgtggagc gaggtcttgt actaggtgta cacaaaccac cagctgccat
481 cagcctcgct aaggttgagc ttgcaccact ttctttgtac tggagacctg tatacactcc
541 acagtacctc atctctccag acgctctcaa gaaactagct ggagagacgt ttccctacac
601 agcctttgat aacaactgtt attccttttg ctgctgggtc ctggacctaa atgactcatg
661 gctgagtagg aggatgatcc agagaacaac tggtttcttc agaccctacc aagactggaa
721 taggaaaccc cttcccacca cggatgactc caaaataaag aaggtagcta acatattcct
781 gtgtgccctg tcctcgctgt tcaccagacc cataaaagat ataataggga agataaggcc
841 tctcaacatc ctcaatattt tagcctcatg tgattggact tttgcaggca tagtggagtc
901 cctaatactc ttggcagaac tctttggagt tttctggaca cccccagatg tgtctgcgat
961 gattgcccct ttactcggtg actacgagct acaaggtcct gcggaccttg cagtggagct
1021 cgtccccgtg gtgatggggg gaattggttt ggtgctaggg ttcaccaaag agaagattgg
1081 gaaaatgttg tcatctgctg cgtccacctt gagagcttgc aaagaccttg gtgcatatgg
1141 actagagatc ctaaagctgt gtatgaagtg gttcttcccg aagaaggagg aagcaaacga
1201 gctagctatg gtgaggtcta ttgaggatgc agtcctagac ctcgaggcaa ttgaaaacaa
1261 ccatatgacc accttgctca aagacaagga cagtctggca acctacatga gaacacttga
1321 ccttgaggag gagaaagcca ggaaactctc aaccaagtct gcctcgcccg acatcgtggg
1381 cacaatcaac gccctcctgg cgagaatcgc tgccgcacgt tctctggtgc atcgggcgaa
1441 ggaggaactt tccagcagac caagacctgt ggtgttgatg atatcaggca ggccaggaat
1501 agggaaaacc caccttgcaa gggaagtggc taagagaatt gcagcctccc tcacaggaga
1561 ccagcgtgtg ggcctcatcc cacgcaatgg cgtcgaccat tgggacgcgt acaaggggga
1621 gagagtcgtc ctatgggacg attatggaat gagcaaccct attcacgatg ccctcaggct
1681 gcaagaactc gctgacactt gccccctcac tctaaactgt gataggattg aaaacaaagg
1741 aaaagtcttt gacagcgatg tcatcattat caccactaac ctggccaacc cagcgccatt
1801 ggactatgtc aactttgaag cgtgctcgag gcgcattgac ttcctcgtgt acgcagaagc
1861 ccctgaggtc gaaaaggcga agcgtgactt cccaggtcaa cctgacatgt ggaagaacgc
1921 tttcagtcct gatttctcac acataaaact agcactggcc ccgcagggtg gttttgacaa
1981 gaacgggaac accccacatg gaaagggcgt catgaagacc ctcaccaccg gctcccttat
2041 tgcccgggca tcagggctac tccatgagag attagatgaa tttgaactac agggcccagc
2101 tctcaccacc ttcaatttcg accgcaacaa agtgcttgcc tttagacagc ttgctgctga
2161 aaataagtat ggattgatgg acacaatgag ggtcgggaaa cagctcaagg atgtcagaac
2221 catgccagag ctcaagcaag cactcaagaa tgtttcaatc aagaagtgtc agatagtgta
2281 tggtggttgc acctacatgc ttgagtctga tggtaagggc aatgtgaaaa ttgacagaat
2341 ccaaagtact gctgtgcaaa tcaacaatga gctggctggt gctctgcacc atttgaggag
2401 tgccagaatc agatactatg tcaagtgtgt ccaggaggcc ctgtattcca tcattcaaat
2461 tgctggggct gcatttgtca ccacgcgcat tgccaagcgc atgaacatac tgagcctatg
2521 gtccaagcca caagtggaag acacagagga tgctaccagc aaggacggat gcccaaaacc
2581 taaggatgat gaggagtttg tcatttcatc tgacgacatc aaagctgagg gcaagaaggg
2641 gaagaacaag actggccgcg gcaagaaaca cacagcattc tcaagcaaag gcctcagtga
2701 tgaagagtat gatgagtaca agagaatcag agaagaaagg aatggcaagt attccataga
2761 agagtacctt caggataggg acaaatacta tgaagaagtg gccattgcca gggcgactga
2821 ggaagacttt tgtgaagagg aggaggccaa gatccggcaa aggatcttta gaccaacaag
2881 aaaacaacgc aaggaggaaa gggcctctct tggtctggtc acaggctctg aaatcaggaa
2941 aagaaaccca gatgacttca aacccaaagg gaaactgtgg gctgacgatg acaggaatgt
3001 ggactacaat gagaaactca gctttgaggc cccaccaagc atttggtcaa gaatagtcaa
3061 ctttggttca ggatggggat tctgggtctc ccctagtctg tttataacat caacccatgt
3121 cataccccag ggtgcaaagg agttctatgg agtccccatc aaacaaatac agatacacaa
3181 gtcaggcgag ttctgccgct tgagattccc aagaccaatc aggactgatg tgacgggcat
3241 gatcttagaa gaaggcgcac ctgagggcac cgtggccaca ctactcatca agaggtccac
3301 tggggaactc atgcccctag cagccagaat ggggacccat gcaaccatga agatccaagg
3361 gcgcactgtt ggaggtcaga tgggcatgct tctgacagga tccaacgcca aaagcatgga
3421 cctgggcact acaccaggtg attgtggctg tccctacatc tacaagagag gcaatgacta
3481 cgtggtcatt ggagtccaca cggctgccgc acgcggggga aacactgtca tatgcgccac
3541 ccaggggagt gagggagagg caacacttga aggtggtgac aacaagggga catactgtgg
3601 tgcaccaatc ctaggtccag ggaatgctcc aacgcttagt accaagacca aattctggag
3661 atcatccaca gtgccactcc cacctggcac ctatgaacca gcctatcttg gtggcaagga
3721 ccctagagtt aagggcggcc cttcactaca gcaagtcatg agggaacagt taaaaccatt
3781 cacagagcca aggggcaaac caccaaagcc aagtgtattg gaagctgcca agaagaccat
3841 catcaatgtt cttgagcaaa caattgaccc acctggaaaa tggtcgttcg cacaagcttg
3901 cgcgtccctt gacaagacca cttccagtgg ccatccgcac cacatgcgga aaaacgactg
3961 ctggaacggg gagtccttca caggcaagct agcagaccag gcttccaaag ccaacctgat
4021 gtatgaagag gggaagaaca tgaccccagt ctacacagct gcgctcaagg atgagttggt
4081 taaaactgat aagatttatg gtaacatcaa gaagaggctt ctctggggct cggacctggc
4141 gactatgatc cggtgtgctc gagctttcgg aggcctgatg gatgagctca aagcacactg
4201 tgtcacgctt cccatcaggg ttggcatgaa tatgaatgag gatggcccca tcatctttga
4261 gaagcattcc aggtacaaac tccactatga tgctgattac tctcggtggg attcaacaca
4321 acagagggcc gtgttggcag cagctctgga aatcatggtt aagttctccc cagaaccaca
4381 tttggcacag gtagttgcgg aagaccttct cgctcctagc gtggtggatg tgggcgactt
4441 cacaatatca atcaacgagg gccttccctc tggggtgcct tgcacctccc aatggaattc
4501 catcgcccac tggcttctca ctctctgtgc gctctctgaa gtcacagacc tgtcccctga
4561 catcatacag gctaactccc tcttctcttt ttatggtgat gatgaaattg ttagcacaga
4621 cataaaattg gacccagaaa aactaacagc aaagctcaga gagtatgggt taaaaccaac
4681 ccgccctgac aaaactgaag gaccccttgt catctctgaa gacctgaatg gcctaacttt
4741 cctgcggaga actgtgtccc gcgacgcagc tggttggttt ggaaagctag agcagagttc
4801 aatactcagg caaatgtact ggactagggg ccccaatcat ggagacccat ctgaaacaat
4861 gattccacac tcccaaaggc ccatacaatt gatgtcccta ctgggtgagg ccgctctcca
4921 cggcccagcc ttttacagca aaatcagcaa attggtcatt gcagagctaa aagaaggtgg
4981 catggatttt tacgtgccca gacaagagcc aatgttcagg tggatgagat tctcagatct
5041 gagcacgtgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga
5101 atgacgccaa cccatctgat gggtcctcag ccagccttgt cccagaggtc aacaatgagg
5161 ttatggcttt ggagcccgta gctggtgccg ctattgcggc acctgtggcg ggccaacaaa
5221 atataattga cccctggatt agaaacaatt ttgtacaagc ccctggtgga gaattcacag
5281 tatcccctag aaatgctcca ggtgaaatac tatggagtgc gcctttaggc cctgatctga
5341 atccctacct ttctcacttg tccagaatgt acaatggtta tgcaggtggt tttgaagtgc
5401 aggtaatcct cgcggggaac gcgttcaccg ctgggaaaat catatttgca gcagtcccac
5461 caaattttcc aactgaaggt ttgagcccca gccaggtcac tatgttcccc aatataataa
5521 tagatgttag gcaattggaa cctgtgttga tccccttacc cgatattagg aataatttct
5581 accattataa tcaatcaaat gaccccacta tcaaattgat agcaatgctg tacacaccac
5641 ttagggctaa taatgccggg gaagatgtct tcacagtttc ttgtcgagtt ctcactagac
5701 cgtcccccga ttttgatttc atatttttgg tgccacccac agttgaatca agaactaaac
5761 catttactgt cccaattttg accgttgaag agatgaccaa ttcgaggttc cccgttcctt
5821 tggagagatt ggtaacaggc cccagtaata atcttgttgt tcaaccacaa aatggcaggt
5881 gcacgaccga tggcgtgctc ctaggtacca ctcaactatc ccctgtcaac atctgcacct
5941 tcagaggtag tgtcactcat attgcaggct ctcgcaacta cacaatgaat ttggcctccc
6001 aaaattggaa caggtatgat ccaacagaag aaatcccagc ccccctagga actccagatt
6061 tcgtggggaa gattcaaggt gtgctcactc aaaccacaaa gggagaaggt tcgacccgcg
6121 cccacacagc tacagtgctc actgggagcg ccgacttctc tccaaaactg ggtagaattc
6181 aatttgccac tgatacagaa aatgatcttg aacccaacca aaacacaagg ttcaccccag
6241 tcggtgttgt acagaatggt ggcactgccc accggaatga accccaacaa tggaatctcc
6301 caacctactc aggcagagac actcacaatg tgcacttggc ccctgctgta gcccccactt
6361 tcccaggcga gcagctcctc tttttcagat ctaccatacc cggatgcagc gggtacccca
6421 acatggattt ggactgtcta cttccccagg aatgggtgca gtatttctac caagaggcag
6481 ccccagcaca atctgatgtg gcccttttaa ggtttgtgaa tccagacaca ggtagggttt
6541 tgtttgagtg caagcttcat aaatcaggct atcttacagt ggctcactct ggccaacatg
6601 atttggtgat tccccccaat ggttatttca gatttgattc ctgggtcaac aatttctaca
6661 cacttgcccc catgggaaat ggaacggggc gtagacgtgc agtataatgg ctggagcttt
6721 cttttctgga ttggcatctg acgtccttgg ctctggactt ggttccctaa tcaatgctgg
6781 ggctggggcc atcaatcaaa aagttgaatt tgaaaacaac aagaagttac aacaagcttc
6841 cttccaattc agtagcaatc tacaacaggc ttcctttcaa catgacaaag atatgctcca
6901 agcacaaatt gaggccacca aaaagctgca acaggaagtg atgagagcta aacaatcaat
6961 gctcctagag ggtggattct ctgagacaga tgcagcccgt ggggcaatca acgcccccat
7021 gacaaaagtt ttggactgga gcggaacaag gtactgggct cctgatgcta gggctacaac
7081 atacaatgca ggccgctttt ccactcccca accctcgggg gcactatcag gaagaactaa
7141 ccttagggcc accgtcccca cccggggttc ccccagtttg tcttctaact cttctactgc
7201 tacttctatg cattcaaatc agaccacatc aacgagactt ggttctacag ctggttctgg
7261 taccagtgtc tcgagcctcc cgtcagctgc aaggactagg agttgggttg aggatcaaaa
7321 taggaatctg tcacctttca tgaggggggc ccacaacatc tcatttgtca ccccaccatc
7381 tagcagatcc tctagccagg gcacagtctc aaccgtgccc aaaggagttt tggactcctg
7441 gactggcgct ttcaacacgc gcaggcagcc tctcttcgct cacatcagac agcgagggga
7501 gtcacgggtg taatgtgaaa agacaaaa
//