Typing tool
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Typing tool
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Complete norovirus genomes
| PQ196513 | GII.4 Sydney | |
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| GII.P16 |
ORF1: 1..1367
ORF2: 1348..2970
ORF3: 2970..3776
LOCUS PQ196513 3791 bp RNA linear VRL 27-MAR-2025
DEFINITION Norovirus GII isolate Hu/GII.4 Sydney[P16]/Solano0018/2023/USA
nonstructural polyprotein, RdRp region, (ORF1) gene, partial cds;
and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION PQ196513
VERSION PQ196513.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 3791)
AUTHORS Barclay,L., Montmayeur,A.M., Cannon,J.L., Mallory,M.L., Reyes,Y.I.,
Wall,H., Baric,R.S., Lindesmith,L.C., Vinje,J. and Chhabra,P.
TITLE Molecular Evolution and Epidemiology of Norovirus GII.4 Viruses in
the United States
JOURNAL J Infect Dis (2025) In press
PUBMED 40036172
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 3791)
AUTHORS Pan,C.Y., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (16-AUG-2024) Viral Gastroenteritis Branch, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. v. 11.1.2; SPAdes v. v. 3.6
Sequencing Technology :: Sanger dideoxy sequencing; Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..3791
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.4 Sydney[P16]/Solano0018/2023/USA"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="08-Feb-2023"
/note="genotype: GII.4 Sydney[P16]"
gene <1..1367
/gene="ORF1"
CDS <1..1367
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XEJ39567.1"
/translation="PSLQQVMRDQLKPFTEPRGKPPRPSVLEAAKQTIINVLEQTLDP
PQKWTYAQACASLDKTTSSGHPHHVRKNEFWNGETFTGKLADQASKANLMFEEGKHMT
PVYTAALKDELVKTEKIYGKIKKRLLWGSDLSTMIRCARSFGGLMDEMKAHCISLPVR
VGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRAVLAAALEIMVRFSAEPQLAQI
VAEDLLAPSVVDVGDFKIAINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTKLSPDII
QANSMFSFYGDDEIVSTDIKLDPEQLTAKLKEYGLKPTRPDKTEGPLIISEDLDGLTF
LRRTVSRDPAGWFGRLDQSSILRQMYWTRGPNHEDPNETMIPHSQRPIQLMALLGEAS
LHGPSFYSRISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPNFVNE
DGVE"
mat_peptide <1..1364
/gene="ORF1"
/product="RdRp"
gene 1348..2970
/gene="ORF2"
CDS 1348..2970
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XEJ39568.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSHNFTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 2970..3776
/gene="ORF3"
CDS 2970..3776
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XEJ39569.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMRVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARITTYNAGHFSTPQPSGALPGRANLRDAVPARGPSTKPS
NSPTATSVHSNQTVSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMKGAYNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 ggccctcctt acaacaggta atgagagatc agttgaagcc attcactgaa cccaggggca
61 aacctccaag accaagtgtt ttggaagcag ccaaacaaac cattatcaat gtccttgaac
121 aaaccctgga tcctccacaa aagtggacat acgcacaggc gtgtgcctca cttgacaaaa
181 ccacctccag cgggcatccc caccatgtcc gaaagaatga attctggaat ggtgagacct
241 tcactggtaa attggcagac caagcatcaa aagcaaacct aatgtttgag gaagggaaac
301 acatgacacc agtgtacaca gcagcactca aggacgagct agtcaagact gagaaaatct
361 atggaaagat caagaagaga ctgctctggg gctctgactt gtccaccatg atccggtgcg
421 ctaggtcatt tggtgggctc atggacgaga tgaaggcaca ctgtatatca ctcccagtgc
481 gagttggcat gaatatgaat gaagatggcc caataatatt tgagaaacat tctaggtaca
541 aatatcacta tgatgcagac tattctcgtt gggactcaac acagcaaagg gcagtattag
601 cagcagcctt ggaaattatg gtcagattct ctgcagaacc acaattggca caaatagtcg
661 ctgaggatct actggcccct agtgtagtag atgtaggaga ctttaaaatt gcaataaatg
721 aagggctccc atctggcgtg ccatgcactt ctcaatggaa ctccattgca cactggctgc
781 taactctctg tgccttgtct gaagtcacca aactgtcccc tgacattata caagcaaatt
841 ccatgttctc attttacggt gatgacgaga ttgtcagcac cgacataaaa ttagaccctg
901 aacagttgac cgccaagttg aaggagtatg gcctgaaacc aacccgccca gacaagactg
961 aggggcctct gatcatcagt gaagatttgg acggactcac tttcctccga aggacggtgt
1021 ctcgtgaccc agctggctgg tttggaagac tggaccaaag ttcgattttg aggcagatgt
1081 attggactag aggaccaaat catgaagacc ccaatgagac aatgataccc cattcccaga
1141 ggcccataca gctcatggca ctgcttggtg aagcctctct tcacggaccc tctttctaca
1201 gtagaatcag taaattggtt ataactgaac tcaaagaagg tgggatggac ttttacgtgc
1261 caaggcagga acccatgttc aggtggatga ggttctctga cttgagcacg tgggagggcg
1321 atcgcaatct ggctcccaac tttgtgaatg aagatggcgt cgaatgacgc caacccatct
1381 gatgggtccg cagccaacct cgtaccagag gtcaacaatg aggttatggc tttggagccc
1441 gttgttggtg ccgctattgc ggcacccgta gcgggccaac aaaatgtaat tgacccctgg
1501 attagaaata actttgtaca agcccctggt ggggagttta cagtatcccc tagaaatgct
1561 ccaggtgaaa tactgtggag cgcaccctta ggccctgacc taaatcccta cctatcccat
1621 ttggccagaa tgtacaatgg ttatgcaggt ggtttcgaag tgcaggtaat tctcgcgggg
1681 aacgcgttca ccgcagggaa gattatattt gcagcagtcc caccaaattt tccaactgaa
1741 ggcttaagcc ctagccaggt taccatgttt ccccatataa tagtagatgt tagacaattg
1801 gaacctgtgc tgatcccctt acccgatgtt aggaataact tctatcatta caatcagtca
1861 aatgactcca ctatcaagtt gatagcaatg ttgtacacac cacttagggc taataatgct
1921 ggggatgatg ttttcacagt ttcgtgccga gttctcacga gaccatcccc cgattttgat
1981 tttatattct tagtaccacc cacagttgag tcaagaacta aaccattctc tgtcccaatt
2041 ttaactgttg aggagatgac caattcaaga ttccccatcc ctttggaaaa gttgttcaca
2101 ggccccagca gtgcatttgt tgttcaacca caaaacggca gatgcacaac tgatggcgtg
2161 ctcctaggta ccacccaact ttctcctgtc aacatctgca ccttcagagg ggacgtcacc
2221 catatcacag gtagtcacaa cttcactatg aatttggctt ctcaaaattg gaacaactat
2281 gacccaacag aagaaatccc agccccccta ggaactccag attttgtggg gaagatccaa
2341 ggcatgctca cccaaaccac aaggacagat ggttcaacac gcggccacaa agctacagtg
2401 tacactggga gcgccgactt tgctccaaaa ctgggtagag ttcaatttga aactgacaca
2461 aaccatgact ttgaagccaa tcagaacaca aagttcaccc cagtaggtgt cattcaagat
2521 ggtagcacca cccaccgaaa cgaaccccaa cagtgggtgc tcccaagtta ctcaggcaga
2581 aatactcaca atgtacattt ggcccccgct gtagccccca cctttccggg tgaacaactc
2641 ctcttcttta gatccaccat gcccggatgc agcgggtacc ccaacatgga tttggactgt
2701 ctgctccccc aggaatgggt gcagtacttc taccaagagg cagccccagc acaatctgat
2761 gtggctctgc taagatttgt aaatccagac acaggtaggg ttctgtttga gtgcaagctt
2821 cacaaatcag gctatgttac ggtggctcac actggtcaac atgatttggt tatccccccc
2881 aatggttact tcaggtttga ttcctgggtc aaccagttct acacgcttgc ccccatggga
2941 aatggaacgg ggcgtagacg tgcagtataa tggctggagc tttctttgct ggattggcat
3001 ctgatgtcct tggctccgga cttggttctc ttatcaatgc tggggctggg gccatcaacc
3061 aaaaagttga gtttgaaaat aacagaaaat tgcaacaagc atccttccaa tttagcagca
3121 atttgcaaca ggcttccttt caacatgata aagagatgct ccaagcacaa attgaggcca
3181 ccaaaaagct acagcaggaa atgatgagag ttaagcaggc aatgctctta gagggtgggt
3241 tctctgagac agatgcagcc cgcggggcaa ttaacgcccc catgacaaag gctttggact
3301 ggagcgggac aaggtactgg gctccagatg ctagaattac aacatacaat gcaggccact
3361 tttccacccc tcaaccatcg ggggcactgc caggaagagc taatctcagg gatgctgtcc
3421 ctgctcgtgg gccctccacc aaaccttcta actctcctac tgccacctct gtgcactcaa
3481 accaaactgt ttcaacgaga cttggttcta cagctggttc tggaaccagt gtctcgagcc
3541 tcccgtcaac tgcaagaact aggagctggg ttgaggatca gaataggaat ttgtcacctt
3601 tcatgaaggg ggcctacaac atatcatttg tcaccccacc atctagcaga tcctctagcc
3661 agggcacagt ctcaaccgtg cccaaagaaa ttttggactc ctggactggc gctttcaaca
3721 cgcgcaggca gcctctcttc gctcacattc gtaagcgagg ggagtcacgg gtgtaatgtg
3781 aaaagacaaa a
//