Human calicivirus
Typing tool

Complete norovirus genomes

PQ100945  GII.7
 GII.P7

Length: 2,716 | 3 CDS 

ORF1: 1..267
ORF2: 248..1870
ORF3: 1870..2643

LOCUS       PQ100945                2716 bp    RNA     linear   VRL 03-AUG-2024
DEFINITION  Norovirus GII isolate GII/Hu/RU/2024/GII.7[P7]/Nizhny_Novgorod132
            nonstructural polyprotein, RdRp region, (ORF1) gene, partial cds;
            and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION   PQ100945
VERSION     PQ100945.1
KEYWORDS    .
SOURCE      Norovirus GII
  ORGANISM  Norovirus GII
            Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
            Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE   1  (bases 1 to 2716)
  AUTHORS   Epifanova,N.V., Oparina,S.V., Sashina,T.A., Alekseeva,A.E.,
            Morozova,O.V., Kashnikov,A.Y. and Novikova,N.A.
  TITLE     The predominance of a previously rare genotype GII.7[P7] in Russia
            in 2023-2024
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2716)
  AUTHORS   Epifanova,N.V., Oparina,S.V., Sashina,T.A., Alekseeva,A.E.,
            Morozova,O.V., Kashnikov,A.Y. and Novikova,N.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2024) Laboratory of Molecular Epidemiology of
            Viral Infections, I.N. Blokhina Nizhny Novgorod Research Institute
            of Epidemiology and Microbiology, Malaya Yamskaya, 71, Nizhny
            Novgorod 603950, Russia
COMMENT     ##Assembly-Data-START##
            Assembly Method       :: Unipro UGENE v. 42.0
            Sequencing Technology :: Illumina
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..2716
                     /organism="Norovirus GII"
                     /mol_type="genomic RNA"
                     /isolate="GII/Hu/RU/2024/GII.7[P7]/Nizhny_Novgorod132"
                     /isolation_source="feces"
                     /host="Homo sapiens"
                     /db_xref="taxon:122929"
                     /geo_loc_name="Russia: Nizhny Novgorod"
                     /collection_date="15-Feb-2024"
                     /note="genotype: GII.7[P7]"
     gene            <1..267
                     /gene="ORF1"
     CDS             <1..267
                     /gene="ORF1"
                     /codon_start=1
                     /product="nonstructural polyprotein"
                     /protein_id="XDI41434.1"
                     /translation="HENPYESMVPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEI
                     KSGGLEFYVPRQEAMFRWMRFSDLSTWEGDRNLAPEGVNEDGVE"
     mat_peptide     <1..264
                     /gene="ORF1"
                     /product="RdRp"
     gene            248..1870
                     /gene="ORF2"
     CDS             248..1870
                     /gene="ORF2"
                     /note="major capsid protein"
                     /codon_start=1
                     /product="VP1"
                     /protein_id="XDI41435.1"
                     /translation="MKMASNDAAPSNDGAAGLVPEINNEVMPLEPVAGASLATPVVGQ
                     QNIIDPWIRNNFVQAPAGEFTVSPRNSPGETLLDLELGPELNPYLAHLARMYNGHAGG
                     MEVQIVLAGNAFTAGKIIFAAIPPGFPYENLSPSQITMCPHVIIDVRQLEPVLLPMPD
                     IRNNFFHYNQGNDPKLRLVAMLYTPLRANNSGDDVFTVSCRVLTKPSPDFEFTFLVPP
                     TVESKTKQFTLPILKISEMTNSRFPVPVEMMYTARNENQVVQPQNGRVTLDGELLGTT
                     PLLAVNICKFKGEVIAKNGDVRSYRMDMEITNTDGTPIDPTEDTPGPIGSPDFQGILF
                     GVASQRNKNEQNPATRAHEANINTGGDQYAPKLAQVKFFSESQDFEVHQPTVFTPVGV
                     AGDTSHPFRQWVLPRYGGHLTNNTHLAPAVAPLFPGEQILFFRSQIPSSGGHELGYMD
                     CLVPQEWVQHFYQEAATAQSEVALIRFINPDTGRVLFEAKLHKQGFITVAHTGDNPIV
                     MPPNGYFRFEAWVNQFYSLAPVGTGNGRRRIQ"
     gene            1870..2643
                     /gene="ORF3"
     CDS             1870..2643
                     /gene="ORF3"
                     /note="minor structural protein; small basic protein"
                     /codon_start=1
                     /product="VP2"
                     /protein_id="XDI41436.1"
                     /translation="MASAFFANLAGGVASNGISSLINAGANAINQKVEFDYNKQLQNA
                     SFSHDKEMLQAQIEATKRLQQEMIDIKRGVLTAAGFSPTDAARGSVGAPMTKLVDWSG
                     TRYWAPGAMRTTGYSGTFTHLPPMQSASYVNNQNRQLFKVDPSPSSSSGSSVSSVKTQ
                     STALSGTSRVDSSSQSTLSTRPSSRTSDWVRSQNERLSPFMNGALQTAYVTPPSSRAS
                     SVSTVSTMPKEVLDSWTPMFNTHRQPLFAHLRRRGESQI"
ORIGIN      
        1 catgagaacc cgtacgagag tatggttcct cattctcagc gggctacaca gctcatggcc
       61 cttcttggtg aggcctcgct gcatggtcca cagttttaca agaaagttag caagatggtc
      121 atcaatgaga ttaaaagtgg tggtctggag ttttatgtgc ccagacaaga ggccatgttc
      181 aggtggatga gattctctga cctcagcaca tgggagggcg atcgcaatct tgctcccgaa
      241 ggtgtgaatg aagatggcgt cgaatgacgc agctccatct aatgatggtg cagcaggcct
      301 cgtgccagag atcaacaatg aggtcatgcc ccttgagccc gtggctggtg catcgctggc
      361 gacaccagtt gtcgggcaac aaaacataat tgatccctgg ataagaaata attttgtaca
      421 agctcctgca ggtgagttca cagtttctcc tagaaattcc cctggtgaaa ctttgcttga
      481 tttggagttg ggaccagagt tgaaccccta tcttgctcat cttgcccgta tgtacaatgg
      541 gcacgctggt ggcatggaag tgcaaattgt gttggctggg aacgcgttca cagctggcaa
      601 gatcatattt gctgccatcc ctccagggtt cccatatgaa aatttgtcac cttcacaaat
      661 tacaatgtgc ccccatgtta taattgatgt tagacaatta gagccagtct tactacctat
      721 gccagatatc agaaacaatt tcttccatta taatcagggt aatgatccaa aattaagact
      781 ggtagctatg ctctatactc ctttaagggc taataattct ggtgatgatg tgttcacagt
      841 ttcttgtagg gttctcacta aaccatcacc tgattttgaa ttcacatttt tggtcccccc
      901 tacagttgaa tccaagacca agcaattcac attgcccatc cttaaaatat cagagatgac
      961 caactcaaga ttcccagtgc cggtggaaat gatgtacaca gcaaggaatg agaatcaagt
     1021 tgtccagcca cagaatggta gggtcacact cgatggcgag ctattgggca ccacgccctt
     1081 gttggctgtc aacatctgca aattcaaggg agaggtcata gctaagaatg gagatgtgag
     1141 atcctatagg atggacatgg aaatcaccaa cactgatggc accccaattg accccactga
     1201 agatacacct ggtcccattg gatcacctga ctttcaaggt atactctttg gcgttgccag
     1261 tcagcgcaac aaaaatgagc agaatcctgc taccagagcc catgaagcca acatcaatac
     1321 tggtggggac caatatgccc ccaaattggc ccaagtaaaa ttcttttcag agtcccagga
     1381 tttcgaggtg caccaaccca cagttttcac cccagttggt gtggcaggtg atacttccca
     1441 ccctttcaga cagtgggtct tgcctcgata tggtggacat ctcaccaaca acactcactt
     1501 ggctccagca gtggcccccc tattcccagg tgagcagatt ctgttcttta gatcacaaat
     1561 acctagttca ggcggccatg aattgggtta catggactgc cttgtcccac aggaatgggt
     1621 ccaacacttc taccaagaag ctgccacagc tcagtctgag gtggcactca taaggttcat
     1681 taaccctgac actggcagag tcctctttga ggccaagcta cacaagcaag gctttataac
     1741 tgtggctcac accggtgaca acccaattgt catgccacca aatgggtact tcagatttga
     1801 agcctgggtc aatcagtttt actcactcgc ccccgtggga actgggaatg ggcgtaggag
     1861 gatccaataa tggccagtgc tttctttgca aatttggcag ggggcgtcgc ctccaatgga
     1921 atcagttcac tcataaatgc tggggctaat gctattaacc aaaaggttga gtttgattat
     1981 aataaacaac tccaaaatgc atccttctcc cacgataaag aaatgctcca agcccaaatt
     2041 gaagccacta aacgtttgca acaagagatg attgacataa aacgaggggt gctgacggct
     2101 gcgggattct ctcccacgga tgccgcgagg ggttctgttg gcgcgccaat gacaaaatta
     2161 gttgattgga gtggtaccag atattgggct cctggtgcca tgaggacaac aggatattca
     2221 ggaactttta ctcacttgcc tcctatgcag tctgcttcat atgttaataa tcagaataga
     2281 cagcttttta aagtagatcc ttctccttct tcttcaagtg gctcttcagt ttcttctgtt
     2341 aaaacacaat caactgctct ctccggcact tcaagggtgg actcttcatc tcagtcaacc
     2401 ctgtcgacca ggccgagctc aaggacatct gactgggtac gtagccaaaa tgaaaggttg
     2461 agccccttca tgaatggagc gttgcaaaca gcgtatgtaa cgccaccatc tagtagggca
     2521 tcaagtgtca gcacagtctc gaccatgccg aaagaggttt tggactcctg gacgcctatg
     2581 tttaacactc acaggcagcc gctcttcgcc cacttgcgta ggcgagggga gtcacagatt
     2641 tagtgaaaag atcaattagg aaagtttgat tagttttctt ttctattatt cctttaattt
     2701 ttcttttaaa aaaaaa
//