Typing tool
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Typing tool
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Complete norovirus genomes
| PP645199 | GII.8 | |
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| GII.P8 |
ORF1: 5..5104
ORF2: 5085..6698
ORF3: 6698..7471
LOCUS PP645199 7490 bp RNA linear VRL 16-APR-2024
DEFINITION Norovirus GII isolate GII/Hu/TH/2023/GII.8/NoV35 nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION PP645199
VERSION PP645199.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7490)
AUTHORS Kongjorn,S., Phatsamarn,T., Roychoudhury,P., Sereewit,J.,
Singchai,P., Sobolik,E.B., Greninger,A.L., Tacharoenmuang,R. and
Rojanawiwat,A.
TITLE Direct Submission
JOURNAL Submitted (10-APR-2024) Virology, University of Washington, 850
Republican St, Seattle, WA 98109, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. 2023; metaspades v. 2024
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7490
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="GII/Hu/TH/2023/GII.8/NoV35"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Thailand"
/collection_date="2023-06-10"
/note="genotype: GII.8"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WZD51302.1"
/translation="MKMASNDATAAAGNFNIANNSENTPPPIKEEASVLSNVKVGFKK
ILGAVPKQPKPPEVKTKDQPRVLVNGKALEVPPPPPNGEDVVYYNSKDDTVYGLPNLT
TVSCEGENLPYTVPPLSEREHRAAPEPLPGTILEMWDGEFYHYAIYVSGGKAIGVHKP
PAAISLATIQLTPISLYWRPVYVPNYLVHPDTLKSLAGEKFPYTAFNNNCYNFCCWVL
DLKDSWLNRRSITRTTGFFKPYQSWNKKPLPTVDDGKIKKVANAVLCALGSLFSKPIK
DLIGKLKPLNFLNLLASCDWTFSGVVETVILVAELFGVFWTPPDVSNFIASLVGDFEL
QGPEDLAVELVPIIMGGVGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVM
KWFFPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTALLKDRDSLLTYMKTLDLEEEKA
RKLSTKSSSPDIVGTINAILARIAAARSLLHRAKEEMYSRPRPVVVMISGRPGVGKTH
MARHLAKSVAGTMSGDQRVGLIPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALALQE
LADTCPVTLNCDRIENKGKMFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEA
PTIEKAKKDFPGQPDMWKEHFKADFSHLKLTLAPQGGFDKNGNTPHGKGTMKTLTQGS
LTARVAGLVHERKDEFQLQGGELQVYNFDTNKVSAFRKLAADNNYGFLETMRVGSSLK
DVKTVEDLKCALKSVSFKECEIIYRNVKYRVSSDGCGKVSIEKLADNNSQTTREIITA
VTRLRQARARYYISCFQDLVYTLLQVAGASFVINRIVKKFNWERWVKAPETDEPTPSN
DKPDTEEEWEIAPKDVDSEGKKGKNKKGRGRKHTAFSSKGLSDEEYDEFKRLREEKQG
RYTIEEYLQDRDRYYEELAVARATEENFCEEEEIKIRQRIFRPTKKQRKEERGVLGLV
TGADIRKRKPDDFQPKGRLWADDSRSVDYNEKIEFEAPPSVWSRIVPLGTGWGFWVSS
NLLITTTHVLPKGVKELFGVDIKQVQVHKSGEFCRFRFPKPVRPDVSGLVLEEGAPEG
TVCSVLIKRSTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGD
CGCPYIYKRGNDIVVAGVHTAAARGGNTVICATQGPDGEAVLEGGEDHGTYCGAPILA
PGKAPKLSTKTKFWRSSPDSLPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEEAKKTVMNVLEQTIEPAKPWTYSQACASLDKTTSSGSPHHVRKNEHW
NGESFTGPLADQASKANLMYEEGKHMDPMYTAALKDELVKTDKIYKKIKKRLLWGSDL
GTMVRCARAFGGLLDSMKESCISLPCRVGMNINEDGPLIFEKHSKYTYHYDADYSRWD
STQQRAVLSAAMEVMVKFSAEPELAQVVAEDLLAPSRLDVGDFVISVQEGLPSGVPCT
SQWNSIAHWILTLSAMSEVSGLSPEVVQANSCFSFYGDDEIVSTDINLDPEKLTRKLR
EYGLVPTRPDKTEGPLVITQDLNGLTFLRRTIVRDPAGWFGKLDRDSILRQLYWTRGP
NHENPFESMIPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQE
AMFRWMRFSDLSTWEGDRNLAPENVNEDGVE"
mat_peptide 5..1009
/gene="ORF1"
/product="p48"
mat_peptide 1010..2107
/gene="ORF1"
/product="NTPase"
mat_peptide 2108..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6698
/gene="ORF2"
CDS 5085..6698
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WZD51303.1"
/translation="MKMASNDAAPSNDGAAGLVPEINHEVMAIEPVAGASLAAPVVGQ
LNIIDPWIRNNFVQAPAGEFTVSPRNAPGEFLLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAVIPPGFPYENLSPAQLTMCPHVVVDVRQLEPILLPMPD
IRNTFFHYNQSNGPKLRLVAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFEFNFLVPP
SVESKTKAFTLPILKISEMTNSRFPIPVDQMYTSRNENIVVQPQNGRVTLDGELQGTT
TLQPVSICGFRGTLQTRLADQPNYTYQVHLENLDGSPVDPTDEVPAPLGTPDFQAQLF
GVVSQRSSDNATRAHEARVNTNDPTFAPQIAQVRFKSPSHDFFDNEPIKFTPVGISVD
SENGYNQWLLPRYGGHLTNNTHLAPSVSPMFPGEQILFFRSFMPGASGHTDGAIDCLL
PQEWVAHFYQEAATAQTDVALIRFVNPDSGRVLFEGKLHKQGFITISNSGDHPIVMPA
NGYFRFEAWVNQFYSLAPVGTGSGRRRVQ"
gene 6698..7471
/gene="ORF3"
CDS 6698..7471
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WZD51304.1"
/translation="MAGAFLAGLAGDVVSSGIGSLINAGANAVNQKVEYDFNRQLQEA
SFKHDKEMLNAQINATTKLQRDMIAIKQGVLTAGGFSPTDAARGSINAPTTKILDWNG
SRYWAPGSMRTTAYSGNFTSQGVKQPTPIVRSVKPQVQQSPAPSSVYSVGSVRSQSTQ
STQLTGSGTVSRAPTPSTTTTLSRTSEWVRSQNDRLSPFMGGALQTAFITPPSSKASS
SSGTVSTVPKEILDSWTPAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgctac cgctgccgct ggcaacttta acattgccaa
61 caacagtgaa aacactcccc ctcccattaa ggaagaggcg agtgtcctat ccaacgtaaa
121 agttggattt aagaaaatat tgggggctgt gcccaagcag cccaagccac cagaagtgaa
181 aaccaaagat cagcccaggg tgctggtcaa tggtaaggcc ttggaggtac cgcccccacc
241 accaaatggt gaagacgtgg tctactataa cagcaaggat gacaccgtgt acggtctacc
301 aaatctaaca acagtcagct gtgaaggtga aaaccttccg tacacagtcc cccctctcag
361 cgagagagag cacagggcag caccagaacc attacctggt accatactag agatgtggga
421 tggtgaattc taccattatg cgatatatgt ctctggtggc aaggccatag gggtgcacaa
481 acccccagct gcaatcagcc ttgccactat ccagcttacg cctatatcgc tttactggag
541 gcccgtttat gtccctaatt acttggtcca ccctgacaca ctcaagagct tagccggtga
601 aaaattccca tacaccgcat ttaacaacaa ctgttacaat ttctgttgct gggttcttga
661 cctgaaagat tcgtggctca accgcagatc aataactaga acaaccggtt tcttcaagcc
721 ttatcagtcc tggaacaaga aaccacttcc gacggtggat gatggaaaaa tcaagaaagt
781 cgccaatgca gtcctatgtg cccttggttc actattctca aaacctatta aggacttgat
841 cgggaagctg aaaccactga atttcttgaa tctcctcgcc tcgtgcgact ggaccttctc
901 cggagtggtt gagaccgtca tactagttgc tgagctgttt ggtgtgtttt ggaccccccc
961 cgacgtgtcg aatttcatcg cgtcactcgt cggggatttt gagctgcaag gtccagagga
1021 tttagctgtg gagttggtgc cgatcatcat gggcggtgtc gggatggtgc tgggattcac
1081 cgccgagaag atcggccgaa tgctatcatc ggctgcatcg acccttaggg cctgtaaaga
1141 cctaggtaac tacgcccttg acatacttaa attggtcatg aagtggttct tcccaaagaa
1201 ggaggaaaag gcagagatgg aaaccttgag ggctatagag gatgctgtct tagacatgga
1261 ggcgattggg aataaccacc tcactgctct gttgaaagac agggacagcc tcctaactta
1321 catgaagact ctagaccttg aagaagaaaa ggcgagaaag ctatccacaa aatcatcgtc
1381 ccctgacatt gtgggtacta tcaatgccat actagccaga attgctgcgg ctaggtctct
1441 cctgcacaga gccaaagaag aaatgtacag cagacctagg cctgtcgtgg tgatgatatc
1501 agggagacca ggggttggta aaacccatat ggctagacac ctcgccaaga gtgtggcggg
1561 caccatgagt ggtgaccaaa gggtgggcct catcccccgc aatggagttg accattggga
1621 tgcctatagg ggagaacgag tcgtcttgtg ggacgactat ggtatgggca acccagtgaa
1681 ggacgccctc gctctgcaag aactagcaga cacttgtcca gtcactctca attgtgacag
1741 gatagagaac aaagggaaga tgtttgacag cgaggtaata atcataacaa ctaatttggc
1801 caaccccgcc ccgcttgatt atgtcaactt tgaagcttgt tcccgtagaa tcgacttcct
1861 cgtctacgca gaagccccaa ctattgagaa ggcgaagaag gattttcccg ggcaaccaga
1921 catgtggaag gagcacttca aagcagactt ctcccacctc aaactcacac tggccccgca
1981 aggcggtttt gacaagaacg gcaacacgcc acatgggaag gggactatga agaccttaac
2041 acagggttcc ctcacagcaa gagtggctgg gctcgtgcac gaaaggaaag atgagtttca
2101 gttacagggt ggagagttgc aggtctacaa ttttgacaca aacaaggtat cggctttcag
2161 gaagcttgct gcagataaca actatgggtt cctggagaca atgagagtcg gctcctcact
2221 caaggacgtc aagacagtgg aagatcttaa atgtgctctt aagagtgtca gtttcaaaga
2281 atgtgaaata atctacagga atgtcaagta ccgcgtatca tcagacggtt gcggtaaggt
2341 cagcatagag aaactggcag ataacaactc ccaaacaacc agagagatta tcacggccgt
2401 cactagacta cgacaggctc gtgctaggta ctacatcagt tgcttccaag acctagtcta
2461 cacactcttg caggttgccg gagcctcatt tgtcattaac agaatagtca agaagttcaa
2521 ctgggaacga tgggtcaaag ctccagaaac agatgaaccc acaccaagta atgacaagcc
2581 cgacactgaa gaggaatggg agatcgcccc caaagatgtg gactctgagg gtaaaaaggg
2641 aaagaacaag aagggcaggg gacgtaagca cactgcgttc tccagcaaag ggctcagtga
2701 tgaggagtat gatgaattca aaagactaag ggaagagaaa cagggccgct acacaataga
2761 ggagtacctc caggacaggg accggtacta tgaagagctg gcagtggccc gggccactga
2821 ggagaacttc tgtgaagagg aagagataaa gatcaggcaa aggatattcc gccccaccaa
2881 aaagcagagg aaggaggagc gtggggttct gggactcgtc acaggagcag acatcaggaa
2941 acggaaaccc gatgacttcc aaccaaaagg aagattgtgg gcagatgact ctaggagcgt
3001 cgactacaat gagaagatcg agtttgaggc tcctcctagc gtctggtcaa gaatcgtccc
3061 gcttggaact ggttgggggt tctgggtctc atccaactta ttaattacca ccacacatgt
3121 gctgcccaaa ggtgttaaag agctttttgg ggtggatatc aaacaagtcc aagttcacaa
3181 atcaggcgaa ttttgcagat tcaggttccc aaaaccagtg aggccagatg tctctgggtt
3241 ggtgttagaa gaaggggccc ccgaaggcac agtgtgctct gttctcatca agaggtctac
3301 aggagagatg atccccctcg cagttaggat gggcacccac gcctctatga agattcaggg
3361 gcgcactgtt ggcggccaga tgggcatgct gctcactgga gccaacgcta agaacatgga
3421 tttgggtacc ggccccgggg attgtggttg cccgtacata tacaagaggg gcaatgacat
3481 cgtagtggcc ggcgtccaca cagcagcggc gcgcgggggc aacacagtca tctgcgcaac
3541 ccaaggacct gatggtgagg cagtgttgga agggggagag gaccacggta cttactgtgg
3601 agccccaata ctggcccctg gcaaagcgcc gaagctcagc acaaagacca agttttggcg
3661 ctcatcccct gattcccttc cccctgggac gtatgaacca gcttaccttg ggggcaagga
3721 cccccgtgtg gagaaagggc cgtcactcca acaagtgatg cgagaccaac tcaaaccctt
3781 cacagaaccc aggggcaagc cacctaggcc gtcagtgctg gaggaagcca agaagacagt
3841 catgaatgta ctggagcaga ccatagaacc agctaagcca tggacctact ctcaagcctg
3901 tgcttcactg gataaaacaa catccagtgg cagtcctcac catgtcagaa agaatgaaca
3961 ctggaacggg gagtctttta ctgggcctct tgcagatcaa gcctcaaaag ccaacctaat
4021 gtatgaggaa ggtaaacata tggaccctat gtacacagca gccctcaaag acgagctggt
4081 aaaaaccgac aaaatctaca agaaaatcaa gaagaggttg ttgtgggggt ctgatctggg
4141 gacaatggtg aggtgtgctc gagcgtttgg aggattgctc gacagcatga aagagagttg
4201 catctcctta ccttgtaggg ttggcatgaa cataaatgaa gatggaccac tcatatttga
4261 aaaacactcc aaatacacct atcactatga tgctgattac tctaggtggg actcaacaca
4321 acagagggcc gtactgagtg cagctatgga ggtaatggtg aagttctctg ctgagccgga
4381 actggctcag gtggttgccg aagacctcct tgcacccagc cgtcttgacg tgggtgactt
4441 tgtcatctcc gttcaagaag gtctcccatc gggtgtcccc tgcacatcac agtggaactc
4501 aattgctcat tggattttga ctcttagtgc tatgtctgag gtctctggtc tttcccctga
4561 ggttgtgcaa gccaactcct gtttctcatt ctatggggat gatgagatag tcagcacaga
4621 cataaatctg gacccagaaa aactcaccag gaaactgagg gagtatggcc tcgtcccaac
4681 aaggccagat aaaactgaag gcccacttgt gattactcag gatttgaatg gtctcacatt
4741 tctgaggcga accatagtgc gggaccccgc aggctggttt ggaaaactgg accgtgactc
4801 cattctaagg cagttatact ggactagagg acccaaccat gagaacccct ttgaaagcat
4861 gattcctcac tcccagagag caacccagtt aatggccctt cttggagaag cctcgctgca
4921 tggtccccag ttttacaaga aggtgagtaa aatggtaatc aacgagatca agagtggtgg
4981 tctggagttt tacgtgccca gacaggaggc catgtttaga tggatgagat tttcagacct
5041 cagcacgtgg gagggcgatc gcaatctggc tcccgagaat gtgaatgaag atggcgtcga
5101 atgacgcagc tccatcgaat gatggcgcgg ctggcctcgt accagagatc aaccatgagg
5161 tcatggccat agagcctgta gcaggagctt ctttagcagc tcctgttgta ggacaactta
5221 atataattga tccctggatt agaaataact ttgtacaagc ccctgctgga gaattcactg
5281 tttcgcctag gaatgctcca ggtgaatttt tattagattt agagttaggt ccagaattga
5341 atccttacct tgctcacctt gcacgcatgt ataatgggca tgcaggtggt atggaggtgc
5401 agatagtgct tgctgggaat gcgttcacag cgggcaaaat attgtttgca gttataccgc
5461 ctggattccc ctatgaaaat ttgtcacctg cacaattgac catgtgccca catgtagtgg
5521 tggatgtgag gcagcttgaa ccaatcttgc tgcccatgcc agacatccgc aacacattct
5581 tccattacaa ccagagcaac gggccaaaac ttagattagt agctatgctt tacacacccc
5641 taagggctaa taatgctggt gatgatgtct tcacagtttc ctgcagggtt ttgactcgcc
5701 catcaccaga ttttgaattt aattttcttg tccccccatc cgttgaatct aagactaaag
5761 ctttcaccct tccaattctt aagatatctg agatgacaaa ttcaagattt cccataccag
5821 ttgaccagat gtacactagt aggaatgaaa atatagttgt tcaaccacaa aatggtagag
5881 tgacacttga tggagagtta cagggcacaa ccacactcca accggtgtcc atttgtggct
5941 tccgagggac gctgcagacc aggctggcag atcaaccaaa ttacacatac caagtgcatc
6001 ttgagaattt ggacggctca cccgttgacc cgacagatga agttccagcc cccctgggga
6061 caccagattt tcaggcccag ctatttggag ttgtcagcca aaggagtagt gataatgcca
6121 ccagggcaca tgaggccagg gtcaacacca acgatcctac cttcgcgccc cagatcgccc
6181 aggtgcgttt caaatcacca tcccacgact tctttgacaa tgagcccatc aaattcacac
6241 cagttggaat cagtgttgat agcgaaaatg gttacaacca atggctccta cccaggtatg
6301 gtggacacct gacaaacaac acccacctgg ccccctctgt gtccccaatg ttccccggcg
6361 agcagattct cttcttccgc tcgttcatgc caggtgccag tggtcacact gatggtgcta
6421 ttgactgcct tttaccacaa gagtgggttg cccacttcta tcaggaggcc gcaactgcgc
6481 aaacagatgt ggctctgatc agatttgtga accccgactc aggcagagtg ctatttgaag
6541 ggaagttgca caagcagggt tttataacca tctccaacag tggggaccac cccattgtta
6601 tgcctgctaa tggatacttc agatttgagg catgggtcaa ccaattttac tctctcgccc
6661 ccgtgggaac tggaagtggg cgcagaagag ttcaataatg gctggagctt ttcttgctgg
6721 tctggctggt gatgtggtgt cctctggcat cgggtcactc atcaatgcag gtgctaatgc
6781 agtgaaccaa aaggttgaat atgacttcaa taggcaactc caagaagctt cttttaaaca
6841 tgacaaggag atgttgaatg ctcaaattaa tgccacaacc aaattgcaaa gggacatgat
6901 tgccattaag cagggggttt tgaccgctgg cggcttttcc cccactgacg ctgcaagggg
6961 ttccatcaat gctccaacca ccaaaattct tgactggaac gggtctaggt actgggcacc
7021 aggatcaatg agaacaacag cgtactctgg caatttcaca tcacagggag ttaagcagcc
7081 cacacccatt gttaggtctg taaaacctca agtacagcaa tctcctgccc cttcttctgt
7141 ttattctgta ggttctgtta ggtcacaatc aacacaatca acccaactaa cagggtcagg
7201 gactgtatca agggcaccca ccccctcaac aaccacaaca ttgtccagaa caagtgagtg
7261 ggtgaggagc cagaatgata ggttgagccc ctttatggga ggcgcactcc agacagcttt
7321 catcacgccc ccatcgagta aggcttcatc ctcatcagga acagtctcaa ccgttcctaa
7381 agaaattttg gactcctgga ctcctgcatt taacacgcgc aggcagccgc tcttcgctca
7441 catacgtaag cgaggggagt cacgggctta gtgaaaagaa tgatttggtt
//