Typing tool
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Typing tool
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Complete norovirus genomes
| MK756037 | GII.4 Sydney | |
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| GII.P16 |
ORF1: 1..4997
ORF2: 4978..6600
ORF3: 6600..7406
LOCUS MK756037 7406 bp RNA linear VRL 11-APR-2019
DEFINITION Norovirus GII isolate Hu/US/2016/GII.P16-GII.4 Sydney/Alameda0792
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION MK756037
VERSION MK756037.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7406)
AUTHORS Barclay,L., Cannon,J.L., Wikswo,M.E., Phillips,A., Browne,H.,
Montmayeur,A.M., Tatusov,R.L., Burke,R.M., Hall,A.J. and Vinje,J.
TITLE Emergence and characterization of multiple viruses associated with
a novel GII.P16 polymerase in the United States, 2015-2018
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7406)
AUTHORS Barclay,L., Cannon,J.L., Johnston,S.H., Montmayeur,A.M.,
Tatusov,R.L., Chhabra,P. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (05-APR-2019) Division of Viral Diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPAdes v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7406
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Alameda0792"
/isolate="Hu/US/2016/GII.P16-GII.4 Sydney/Alameda0792"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="16-Jun-2016"
/note="genotype: GII.P16-GII.4 Sydney"
gene <1..4997
/gene="ORF1"
CDS <1..4997
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QBW96065.1"
/translation="LKKALGARPKQPAPRDEPQKPPRPPTPELVKRIPPPPPNGEEEE
EPVIRYEVKSGISGLPELTTVPQPDVANTAFSVPPLSLRENREAKEPLTGAILEMWDG
EIYHYGLYVEKGLVLGVHKPPAAISMARVELTPLSLYWRVVYTPQYLISPETLRRLNG
EAFPYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKI
KKVANIFLCSLSTLFTRPIKDLIGKIKPLNILNILATCDWTFAGIVESLILLAELFGV
FWTPPDVSAMIAPLLGEYELQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAAS
TLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLL
KDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGTINALLARIAAARSLVHRAKEELS
SRIRPVVVMISGKPGIGKTHLAREVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERV
VLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPL
DYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGF
DKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDEFELQGPTITTFNFDRNRITAFRQ
LAAENKYGLVDTMKVGNQLKGVKTMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGK
VLVEKVKNTSVQTNNELAGALHHLKHARIRYYVKCVQEAIYSIIQIAGAAFVTTRIAR
RMNIQELWSKPQLDQNESETKEEAPKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTA
FSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIK
IRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDF
EAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCR
FRFPKPIRPDVTGMILEEGAPEGTVATVLIKRPTGELMPLAARMGTHATMKIQGRMVG
GQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQG
SEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRD
PRVKGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQ
ACASLDKTTSSGHPHHVRKNEFWNGETFTGKLADQASKANLMFEEGKHMTPVYTAALK
DELVKTEKIYGKIKKRLLWGSDLSTMIRCARSFGGLMDEMKAHCISLPVRVGMNMNED
GPIIFEKHSRYKYHYDADYSRWDSTQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAP
SVVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSF
YGDDEIVSTDIKLDPEQLTAKLKEYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRD
PAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYS
KISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..893
/gene="ORF1"
/product="p48"
mat_peptide 894..1991
/gene="ORF1"
/product="NTPase"
mat_peptide 1992..2522
/gene="ORF1"
/product="p22"
mat_peptide 2523..2921
/gene="ORF1"
/product="VPg"
mat_peptide 2922..3464
/gene="ORF1"
/product="Pro"
mat_peptide 3465..4994
/gene="ORF1"
/product="RdRp"
gene 4978..6600
/gene="ORF2"
CDS 4978..6600
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QBW96066.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRVV"
gene 6600..7406
/gene="ORF3"
CDS 6600..7406
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QBW96067.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAVLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANLRDAVPARGPSNKSS
NSSTVTSVYSNQTISTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 ccttaaagaa agccctcggg gctaggccca aacagcccgc cccgagagac gaaccacaaa
61 agcccccaag accaccaact cccgagttgg tcaagaggat accccctcct ccacctaatg
121 gcgaagaaga agaagaacca gtcattaggt atgaggttaa gagtgggatc tctggcctgc
181 ccgagctcac aacagtcccc caaccggacg tggccaacac agcattcagt gttccaccac
241 tgagcttgag agaaaacagg gaggccaagg aaccgctaac aggggcaata ttagagatgt
301 gggatggaga gatataccac tatggcttgt acgtggagaa aggcttagtg ttgggtgtgc
361 acaaaccacc tgcagccata agcatggcaa gagtggagct gacgccgctg tcattgtact
421 ggcgtgtggt gtacactccc caatacctca tctcccctga aactctcagg aggctcaacg
481 gagaggcgtt cccttacacc gccttcgaca acaactgcta tgccttctgc tgctgggtgt
541 tagacctcaa tgactcatgg cttagcagga ggatggtgca aagaacaacg ggcttcttca
601 gaccttacca agagtggaac agaaaacccc tgcctaccat ggatgactcc aaaattaaga
661 aggtagcaaa tatattccta tgttcattgt ccacgttatt caccagaccc ataaaagacc
721 tcataggaaa aattaaacca ttaaacatat tgaacatcct ggcaacgtgt gactggacgt
781 ttgccggaat agtggaatct ctgatattac ttgctgaact cttcggagtt ttctggacac
841 ccccagatgt gtctgctatg atcgctccct tactcgggga atacgagttg caagggccag
901 aagacctcgc cgttgaactc gtacctgtgg taatgggagg gattggtttg gtgttgggat
961 tcaccaaaga gaaaattggc aaaatgttgt cctcagcagc atcaacgctc agggcttgca
1021 aagatcttgg tgcctatggc ttagagatac tcaaattggt catgaagtgg ttcttcccaa
1081 agaaagagga ggccaatgag ctagccatgg tgagggccat agaggatgcc gtactagatc
1141 ttgaggcaat agaaaataac cacatgacaa ccctgttgaa agacaaagac agcttagcaa
1201 catacatgaa aacactggac atggaggagg agaaagccag aaggttgtcc acaaaatctg
1261 catcccctga catagttggg acaatcaacg ccctgctggc tcgaatagca gcggccaggt
1321 cattagtcca cagggccaag gaagagctat ctagcaggat aagaccagta gttgttatga
1381 tatctggcaa accaggaata ggcaaaactc atctggccag ggaggtggca agaaaggtgg
1441 catccactct cacaggggat caaagagtcg gactcatacc aagaaacggt gtggaccatt
1501 gggatgcata caaaggtgag agagtcgtgc tgtgggacga ctatggcatg agtaacccca
1561 ttcatgatgc tcttcgcata caagaattgg ctgatacgtg tccccttacc ttaaattgtg
1621 acagaattga aaataaggga aaagtttttg acagtgaagt cataataatt acaacaaacc
1681 ttgccaatcc agccccactt gattatgtca actttgaggc ctgttccagg agaattgatt
1741 tcctggtgta cgctgaggca ccagaagtag aaaaggcaaa acgggacttt cctggtcagc
1801 cagatatgtg gaaggacgcc ttcaagccgg acttttcaca catcaagcta cagcttgcac
1861 ctcagggcgg ctttgacaag aatggcaaca ccccacatgg gaaaggagtg atgaagaccc
1921 tcactaccgg ttctctgatt gcccgtgcat caggcctact gcatgagagg atggatgaat
1981 ttgaactcca aggtcccaca atcaccacct tcaatttcga ccggaacaga atcacagcat
2041 tcagacaatt ggctgcagaa aacaagtatg gattggtgga taccatgaaa gttggcaatc
2101 aactaaaagg agtgaaaacc atggaagaac tcaaacaagc aatcaggaat gtgaccatca
2161 agaggtgccg gatcatctac ggtggctcta cgtacgacct tgaatctgat ggcaagggca
2221 aagttttggt ggaaaaggtc aagaacacct ctgtacagac caacaacgag ttggccggag
2281 ccctgcacca tctcaaacac gcccgaatca ggtactatgt caaatgtgtg caagaagcaa
2341 tctactccat catacaaatt gccggcgctg cgtttgtcac cacgcgcatt gcacgccgca
2401 tgaacataca agaactctgg tcgaagccac aattagatca aaatgaatca gagactaagg
2461 aagaggcccc caagtcagaa gacgacgagt tcatcatatc ttctaaggac atcaaggagg
2521 aaggaaagaa gggcaaaaac aaaactggcc gtggcaagaa acacactgca ttctccagca
2581 agggtttgag cgatgaggag tatgacgagt acaagaggat aagagaagag agaaatggga
2641 agtactctat agaggagtat cttcaagata gagacaggta ctatgaggag ctcgccattg
2701 ccaaggccac agaagaagac ttctgtgaag aggaggagat caaaatccgt cagagaattt
2761 tccgtcccac caggaaacaa agaaaggaag agagggccac attagggcta gtaacaggtt
2821 cagaaatcag aaaaagaaac cctgatgact tcaaacccaa agggaagctg tgggccgatg
2881 acaacagaag tgttgactac aatgagaaac tggactttga ggccccccca agcatatggt
2941 ctaggattgt gagctttggt tctggctggg gcttctgggt atcaccaagc ctgttcataa
3001 catcaactca tgtaatcccc gcaggcataa cagaagcgtt tggagtcccc atcaaacaaa
3061 ttcagatcca caaatcaggt gaattttgcc gattcagatt cccaaaacca attagaccag
3121 atgtgacagg aatgatcttg gaagaaggtg cgcctgaagg caccgtggca actgtgctca
3181 tcaaacgccc caccggagag ctcatgcctc ttgcagccag gatgggaaca cacgcaacca
3241 tgaaaattca aggccgcatg gttggcggac agatgggtat gttgctcact ggatcaaatg
3301 ctaaaggaat ggatttggga acaactcctg gtgactgtgg ctgtccttac atctataaaa
3361 ggggcaatga ctacatagtc attggggtgc acactgcagc agcccgtggt ggaaacaccg
3421 tcatctgtgc tacacaggga agtgagggtg aggcaactct tgagggtgga gacgacaaag
3481 gaacatactg tggggcaccc attctaggcc ctgggggtgc accaaaattg agcaccaaaa
3541 ccaaattttg gaggtcatcg aatacgcccc ttccaccagg gacatatgag cctgcctacc
3601 tcggtggccg tgatccgcgt gttaagggtg ggccctcctt gcagcaggta atgagagacc
3661 agttgaagcc attcactgaa cccaggggca aacctccaag accaagtgta ttagaagcag
3721 ccaaacaaac cattatcaat gtcctcgagc aaaccctgga tcctccacaa aaatggacat
3781 acgcacaggc gtgtgcctca cttgacaaaa ccacctccag cgggcatccc catcacgtcc
3841 gaaagaatga attctggaat ggtgagacct tcactggtaa attggcagac caagcatcaa
3901 aagcaaacct aatgtttgag gaagggaaac acatgacacc agtgtataca gcagcactca
3961 aggatgagct agtcaagact gagaaaatct atggaaagat caagaagaga ctgctctggg
4021 gctctgactt gtccaccatg atccggtgcg ctaggtcatt tggtgggctc atggacgaga
4081 tgaaggcaca ctgcatatca ctcccagtac gagttggcat gaatatgaat gaagatggcc
4141 caataatatt tgagaaacat tccagatata aatatcacta tgatgcagac tactctcgtt
4201 gggattcaac acaacagagg gcagtactag cagcagcttt ggaaatcatg gtcagattct
4261 ctgcagaacc acaattggca caaatagtcg ctgaggatct gctggcccct agtgtagtag
4321 atgtaggaga ctttaaaatc acaataaatg aagggctccc atctggtgtg ccatgcactt
4381 ctcaatggaa ctccatcgca cactggctgc taactctctg tgccttgtct gaagtcacca
4441 aactgtcccc tgacattata caagcaaatt ccatgttctc attttacggt gatgacgaga
4501 ttgtcagcac cgacataaaa ttggaccctg aacagttaac cgccaagttg aaggagtacg
4561 gcctgaaacc aacccgccca gacaagaccg agggacccct gatcatcagt gaagatttga
4621 acggactcac tttcctccga aggacggtga ctcgtgaccc agctggctgg tttggaaaac
4681 tggaccaaag ctcaattttg aggcagatgt actggactag aggaccaaat catgaagacc
4741 ccaatgagac aatgataccc cattctcaaa gacccataca gctcatggca ctgcttggtg
4801 aagcctctct tcacggaccc tctttctaca gtaaaatcag taaattggtc ataactgaac
4861 tcaaagaagg tgggatggac ttttacgtgc caaggcagga acccatgttc aggtggatga
4921 ggttttctga cttgagcacg tgggagggcg atcgcaatct ggctcccaat tttgtgaatg
4981 aagatggcgt cgagtgacgc caacccatct gatgggtccg cagccaacct cgtaccagag
5041 gtcaacaatg aggttatggc tttggagccc gttgttggtg ccgctattgc ggcacctgta
5101 gcgggccaac aaaatgtaat tgacccctgg attagaaata attttgtaca agcccctggt
5161 ggggagttta cagtatcccc tagaaacgct ccaggtgaaa tactatggag cgcgccccta
5221 ggccctgacc taaatcccta cctgtcccat ttggccagaa tgtacaatgg ttatgcaggt
5281 ggttttgaag tgcaagtaat tctcgcgggg aacgcgttca ccgccgggaa gatcatattt
5341 gcagcagtcc caccaaattt tccaactgaa ggcttaagtc ctagccaagt cactatgttc
5401 ccccatataa tagtagatgt cagacaatta gaacctgtgc tgattccctt acccgatgtt
5461 aggaataatt tctatcatta taatcagtca aatgactcca ctattaagtt gatagcaatg
5521 ttgtatacac cacttagggc taataatgct ggggatgatg ttttcacagt ttcgtgccga
5581 gttctcacga gaccatcccc cgattttgat ttcatatttt tagtgccacc cacagttgag
5641 tcaagaacta aaccattctc tgtcccagtt ttaactgttg aggagatgac caattcaaga
5701 ttccccattc ctttggaaaa gttgttcacg ggccccagca gtgcctttgt tgttcaacca
5761 caaaacggca ggtgcacaac tgatggcgtg ctcctaggca ccacccaact gtctcctgtc
5821 aacatctgca ccttcagagg ggatgtcacc cacatcacag gtagtcgcaa ctacacaatg
5881 aatttggctt ctcaaaattg gaacaattac gacccaacag aagaaatccc agcccctcta
5941 ggaactccag attttgtggg gaagattcaa ggcatgctca cccaaaccac aaggacagat
6001 ggttcaacac gcggccacaa agctacagtg tacactggga gcgccgactt tgctccaaag
6061 ctgggtagag ttcaatttga aactgacaca gaccatgatt ttgaagctaa tcaaaacaca
6121 aagttcaccc cagtcggtgt catccaagat ggtagcacca cccaccgaaa cgaaccccaa
6181 cagtgggtgc tcccaagtta ctcaggcaga aatactcaca atgtacatct ggcccccgct
6241 gtagccccca cctttccggg tgaacaactt ctcttcttca gatccaccat gcccggatgc
6301 agcgggtacc ccaacatgga tttggactgt ctgctccccc aggaatgggt acagtacttc
6361 taccaagagg cagccccagc acaatctgat gtggctctgc taagatttgt gaatccagac
6421 acaggtaggg ttttgtttga gtgcaagctt cacaaatcag gctatgttac agtggctcac
6481 actggccaac atgatttggt tatccctccc aatggttact ttaggtttga ttcctgggtc
6541 aaccagttct acacgcttgc ccccatggga aatggaacgg ggcgtagacg tgtagtataa
6601 tggctggagc tttctttgct ggattggcat ctgatgtcct tggctctgga cttggttccc
6661 tcatcaatgc tggggctggg gccatcaacc aaaaagttga gtttgaaaat aacagaaaat
6721 tgcaacaagc atccttccaa tttagcagca atctgcaaca ggcttccttt caacatgata
6781 aagagatgct ccaagcacaa attgaggcca ccaaaaagct acaacaggaa atgatgaaag
6841 ttaagcaggc agtgctccta gagggtgggt tctctgagac agatgcagcc cgcggggcaa
6901 ttaacgcccc catgacaaaa gctttggatt ggagcgggac aaggtactgg gctcccgatg
6961 ctaggactac aacatacaat gcaggccgct tttccacccc tcaaccatcg ggggcactgc
7021 caggaagagc taatcttagg gatgctgtcc ctgctcgggg accctccaac aaatcttcta
7081 actcttctac tgtcacctct gtgtactcaa atcaaactat ttcaacgaga cttggttcta
7141 cagctggttc tggaaccagt gtctcgagcc tcccgtcaac tgcaaggact aggagctggg
7201 ttgaggatca aagtaggaat ttgtcacctt tcatgagggg ggcccacaac atatcatttg
7261 tcaccccacc atctagcaga tcctctagcc aaggcacagt ctcaaccgtg cctaaagaga
7321 ttttggactc ctggactggc gctttcaaca cgcgcaggca gcctctcttc gctcacattc
7381 gtaagcgagg ggagtcacgg gtgtaa
//